A New Limit on Signals of Lorentz Violation in Electrodynamics

We describe the results of an experiment to test for spacetime anisotropy terms that might exist from Lorentz violations. The apparatus consists of a pair of cylindrical superconducting cavity-stabilized oscillators operating in the TM_{010} mode with one axis east-west and the other vertical. Spatial anisotropy is detected by monitoring the beat frequency at the sidereal rate and its first harmonic. We see no anisotropy to a part in 10^{13}. This puts a comparable bound on four linear combinations of parameters in the general Standard Model extension, and a weaker bound of <4 x 10^{-9} on three others.Comment: 4 pages, 3 figures, 2 table

A variable neurodegenerative phenotype with polymerase gamma mutation

mtDNA replication and repair, causes mitochondrial diseases including autosomal dominant progressive external ophthalmoplegia (PEO),1 childhood hepato-encephalopathy (Alpers– Huttenlocher syndrome), adult-onset spinocerebellar ataxia, and sensory nerve degeneration with dysarthria and ophthalmoparesis (SANDO)

Maximum growth and decay rates of autotrophic biomass to simulate nitrogen removal at 10°C with municipal activated sludge plants

The present study aims at determining most likely values for the maximum growth rate (μA, max) and the endogenous decay rate (bA) of nitrifiers for activated sludge processes treating municipal wastewater operated at low temperature (10°C). The work used nitrification rate data measured on 10 full-scale plants and 2 pilot plants fed with domestic sewage. This set of data was combined with a modelling and a theoretical approach. The unified values (μA, max = 0.45·d-1 and bA = 0.13·d-1) were obtained at 10°C for the kinetic parameters of the autotrophic biomass in the SRT range 10 to 50 d. In addition, the factors affecting the expected nitrification rate (rv, nit) were established by a theoretical approach and confirmed by experimental results. For a given SRT, a linear relationship with the nitrogen volumetric loading rate was shown. The COD/TKN ratio of the influent on the nitrification rate was demonstrated. Finally, an operational tool for the verification of the nitrification rate in the design procedure of activated sludge processes is proposed.Keywords: nitrification; kinetics; low temperature; autotrophic biomass, maximum growth rate; decay rat

Anoxic and aerobic values for the yield coefficient of the heterotrophic biomass: Determination at full-scale plants and consequences on simulations

The present study aims at optimising the nitrification and denitrification phases at intermittently aerated process (activated sludge) removing nitrogen from municipal wastewater. The nitrogen removal performance recorded at 22 intermittently aerated plants was compared to the results obtained from the simulations given by the widely used ASM1. It is shown that simulations with a single value for the heterotrophic yield with any electron acceptor over-predict the nitrate concentration in the effluent of treatment plants. The reduction of this coefficient by 20% for anoxic conditions reduces the nitrate concentration by 10 g N&#183;m-3. It significantly improves the accuracy of the predictions of nitrate concentrations in treatedeffluents compare to real data. Simulations with dual values (aerobic and anoxic conditions) for heterotrophic yield (modified ASM1) were then used to determine the practical daily aerobic time interval to meet a given nitrogen discharge objective. Finally, to support design decisions, the relevance of a pre-denitrification configuration in front of an intermittently aerated tank was studied. It is shown that when the load of BOD5 is below the conventional design value, a small contribution of the anoxic zone to nitrate removal occurs, except for over-aerated plants. When plants receive a higher load of BOD5, the modified ASM1 suggests that the anoxic zone has a higher contribution to nitrogen removal, for both correctly and over-aerated plants

Lessons to be learned from the coherent photoproduction of pseudoscalar mesons

We study the coherent photoproduction of pseudoscalar mesons---particularly of neutral pions---placing special emphasis on the various sources that put into question earlier nonrelativistic-impulse-approximation calculations. These include: final-state interactions, relativistic effects, off-shell ambiguities, and violations to the impulse approximation. We establish that, while distortions play an essential role in the modification of the coherent cross section, the uncertainty in our results due to the various choices of optical-potential models is relatively small (of at most 30%). By far the largest uncertainty emerges from the ambiguity in extending the many on-shell-equivalent representations of the elementary amplitude off the mass shell. Indeed, relativistic impulse-approximation calculations that include the same pionic distortions, the same nuclear-structure model, and two sets of elementary amplitudes that are identical on-shell, lead to variations in the magnitude of the coherent cross section by up to factors of five. Finally, we address qualitatively the assumption of locality implicit in most impulse-approximation treatments, and suggest that the coherent reaction probes---in addition to the nuclear density---the polarization structure of the nucleus.Comment: Manuscript is 27 pages long and includes 11 eps figure

Gauge Independence of IR singularities in Non-Commutative QFT - and Interpolating Gauges

IR divergences of a non-commutative U(1) Maxwell theory are discussed at the one-loop level using an interpolating gauge to show that quadratic IR divergences are independent not only from a covariant gauge fixing but also independent from an axial gauge fixing.Comment: 11 pages, 2 figures, v1 minor correction

{HandVoxNet}: {D}eep Voxel-Based Network for {3D} Hand Shape and Pose Estimation from a Single Depth Map

3D hand shape and pose estimation from a single depth map is a new and challenging computer vision problem with many applications. The state-of-the-art methods directly regress 3D hand meshes from 2D depth images via 2D convolutional neural networks, which leads to artefacts in the estimations due to perspective distortions in the images. In contrast, we propose a novel architecture with 3D convolutions trained in a weakly-supervised manner. The input to our method is a 3D voxelized depth map, and we rely on two hand shape representations. The first one is the 3D voxelized grid of the shape which is accurate but does not preserve the mesh topology and the number of mesh vertices. The second representation is the 3D hand surface which is less accurate but does not suffer from the limitations of the first representation. We combine the advantages of these two representations by registering the hand surface to the voxelized hand shape. In the extensive experiments, the proposed approach improves over the state of the art by 47.8% on the SynHand5M dataset. Moreover, our augmentation policy for voxelized depth maps further enhances the accuracy of 3D hand pose estimation on real data. Our method produces visually more reasonable and realistic hand shapes on NYU and BigHand2.2M datasets compared to the existing approaches

Na2IrO3 as a spin-orbit-assisted antiferromagnetic insulator with a 340 meV gap

We study Na2IrO3 by ARPES, optics, and band structure calculations in the local-density approximation (LDA). The weak dispersion of the Ir 5d-t2g manifold highlights the importance of structural distortions and spin-orbit coupling (SO) in driving the system closer to a Mott transition. We detect an insulating gap {\Delta}_gap = 340 meV which, at variance with a Slater-type description, is already open at 300 K and does not show significant temperature dependence even across T_N ~ 15 K. An LDA analysis with the inclusion of SO and Coulomb repulsion U reveals that, while the prodromes of an underlying insulating state are already found in LDA+SO, the correct gap magnitude can only be reproduced by LDA+SO+U, with U = 3 eV. This establishes Na2IrO3 as a novel type of Mott-like correlated insulator in which Coulomb and relativistic effects have to be treated on an equal footing.Comment: Accepted in Physical Review Letters. Auxiliary and related material can be found at: http://www.phas.ubc.ca/~quantmat/ARPES/PUBLICATIONS/articles.htm

A misplaced lncRNA causes brachydactyly in humans

Translocations are chromosomal rearrangements that are frequently associated with a variety of disease states and developmental disorders. We identified 2 families with brachydactyly type E (BDE) resulting from different translocations affecting chromosome 12p. Both translocations caused downregulation of the parathyroid hormone-like hormone (PTHLH) gene by disrupting the cis-regulatory landscape. Using chromosome conformation capturing, we identified a regulator on chromosome 12q that interacts in cis with PTHLH over a 24.4-megabase distance and in trans with the sex-determining region Y-box 9 (SOX9) gene on chromosome 17q. The element also harbored a long noncoding RNA (lncRNA). Silencing of the lncRNA, PTHLH, or SOX9 revealed a feedback mechanism involving an expression-dependent network in humans. In the BDE patients, the human lncRNA was upregulated by the disrupted chromosomal association. Moreover, the lncRNA occupancy at the PTHLH locus was reduced. Our results document what we believe to be a novel in cis- and in trans-acting DNA and lncRNA regulatory feedback element that is reciprocally regulated by coding genes. Furthermore, our findings provide a systematic and combinatorial view of how enhancers encoding lncRNAs may affect gene expression in normal development

Progressive ataxia with oculo-palatal tremor and optic atrophy

The final publication is available at Springer via doi: 10.​1007/​s00415-013-7136-