Lady Di - Die moderne Madonna

Die authentischen Bekundungen von Trauer und Wertschätzung, die der bei einem Autounfall in Paris ums Leben gekommenen Prinzessin Diana weltweit entgegengebracht und seit Jahren von mehreren Seiten instrumentalisiert werden, sind unübersehbar. Das Leben und Sterben der Prinzessin von Wales ist nach Ansicht der Autoren geeignet, einer populären Mythenbildung in der modernen Gesellschaft Substanz zu verleihen. Vor allem bietet es die Möglichkeit, einen modernen Kult zu etablieren, der sich im Zuge politischer Opportunitäten und kommerzieller Interessen steuern und nutzen lässt. Doch was machte Lady Di zu einer derart idealen Kultfigur? Die Autoren zeigen in ihrem Beitrag, dass die Formen der alltäglichen Ehrbezeugungen und der Idolisierung der 'Königin der Herzen' auffallend der einer christlichen Heiligen ähnelt. Die massenmediale Modellierung und die drängenden Erwartungshaltungen ihrer Verehrer formten sie zu einer der herausragenden säkularen Heiligen des ausgehenden 20. Jahrhunderts und posthum zu einer Ikone, die mit den unspezifischen religiösen Orientierungen einer modernen Gesellschaft korrespondiert. (ICI2

Lady Di - die Moderne Madonna

Die authentischen Bekundungen von Trauer und Wertschätzung, die der bei einem Autounfall in Paris ums Leben gekommenen Prinzessin Diana weltweit entgegengebracht und seit Jahren von mehreren Seiten instrumentalisiert werden, sind unübersehbar. Das Leben und Sterben der Prinzessin von Wales ist nach Ansicht der Autoren geeignet, einer populären Mythenbildung in der modernen Gesellschaft Substanz zu verleihen. Vor allem bietet es die Möglichkeit, einen modernen Kult zu etablieren, der sich im Zuge politischer Opportunitäten und kommerzieller Interessen steuern und nutzen lässt. Doch was machte Lady Di zu einer derart idealen Kultfigur? Die Autoren zeigen in ihrem Beitrag, dass die Formen der alltäglichen Ehrbezeugungen und der Idolisierung der "Königin der Herzen" auffallend der einer christlichen Heiligen ähnelt. Die massenmediale Modellierung und die drängenden Erwartungshaltungen ihrer Verehrer formten sie zu einer der herausragenden säkularen Heiligen des ausgehenden 20. Jahrhunderts und posthum zu einer Ikone, die mit den unspezifischen religiösen Orientierungen einer modernen Gesellschaft korrespondiert. (ICI2

Striking structural and functional similarities suggest that intestinal sucrase-isomaltase, human lysosomal α-glucosidase and Schwanniomyces occidentalis glucoamylase are derived from a common ancestral gene

AbstractSequence comparison of the primary structure of the yeast Schwanniomyces occidentalis glucoamylase (GAM) with GAMs in different microorganisms did not reveal significant similarities. By contrast, striking similarities were, surprisingly, found with 3 mammalian secretory and integral membrane proteins: the 2 subunits of intestinal brush border sucrase-isomaltase and human lysosomal α-glucosidase. The similarities among these proteins are found as clusters of up to 8 amino acids and distributed all over the protein sequences. The major sequence differences are found in the N-terminal regions accounting, probably, for the different cellular locations of these proteins. The high level of similarities between sucrase, isomaltase, Sch. occidentalis GAM and human lysosomal α-glucosidase suggest that these proteins are derived from the same ancestral gene. To our knowledge, this is the first report that describes similarities between a yeast secretory protein and mammalian secretory and integral membrane proteins

A Novel Data Fusion Technique for Snow Cover Retrieval

© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.This paper presents a novel data fusion technique for improving the snow cover monitoring for a mesoscale Alpine region, in particular in those areas where two information sources disagree. The presented methodological innovation consists in the integration of remote-sensing data products and the numerical simulation results by means of a machine learning classifier (support vector machine), capable to extract information from their quality measures. This differs from the existing approaches where remote sensing is only used for model tuning or data assimilation. The technique has been tested to generate a time series of about 1300 snow maps for the period between October 2012 and July 2016. The results show an average agreement between the fused product and the reference ground data of 96%, compared to 90% of the moderate-resolution imaging spectroradiometer (MODIS) data product and 92% of the numerical model simulation. Moreover, one of the most important results is observed from the analysis of snow cover area (SCA) time series, where the fused product seems to overcome the well-known underestimation of snow in forest of the MODIS product, by accurately reproducing the SCA peaks of winter season

The importance of snowmelt spatiotemporal variability for isotope-based hydrograph separation in a high-elevation catchment

Seasonal snow cover is an important temporary water storage in high-elevation regions. Especially in remote areas, the available data are often insufficient to accurately quantify snowmelt contributions to streamflow. The limited knowledge about the spatiotemporal variability of the snowmelt isotopic composition, as well as pronounced spatial variation in snowmelt rates, leads to high uncertainties in applying the isotope-based hydrograph separation method. The stable isotopic signatures of snowmelt water samples collected during two spring 2014 snowmelt events at a north- and a south-facing slope were volume weighted with snowmelt rates derived from a distributed physicsbased snow model in order to transfer the measured plotscale isotopic composition of snowmelt to the catchment scale. The observed δ$^{18}$O values and modeled snowmelt rates showed distinct inter- and intra-event variations, as well as marked differences between north- and south-facing slopes. Accounting for these differences, two-component isotopic hydrograph separation revealed snowmelt contributions to streamflow of 35±3 and 75±14% for the early and peak melt season, respectively. These values differed from those determined by formerly used weighting methods (e.g., using observed plot-scale melt rates) or considering either the north- or south-facing slope by up to 5 and 15 %, respectively

Short term outcome after left atrial appendage occlusion with the AMPLATZER Amulet and WATCHMAN device: results from the ORIGINAL registry (saxOnian RegIstry analyzinG and followINg left atrial Appendage cLosure)

Background: Various randomized multicenter studies have shown that percutaneous left atrial appendage closure (LAAC) is not inferior in stroke prevention compared to vitamin K antagonists (VKA) and can be performed safely and effectively. Aims: The prospective multicenter ORIGINAL registry in the Free State of Saxony (saxOnian RegIstry analyzinG and followINg left atrial Appendage cLosure) investigated the efficiency and safety of LAAC with Watchman or Amulet device in a real word setting. A special focus was put on the influence of LAAC frequency on periprocedural efficiency and safety. Methods and results: The total of 482 consecutive patients (Abbott Amulet N = 93 and Boston Scientific Watchman N = 389) were included in the periinterventional analyses. After 6 weeks, 353 patients completed the first follow-up including transoesophageal echocardiography (TEE) (73.2%). Successful LAAC could be performed in more than 94%. The complication rate does not significantly differ between device types (p = 0.92) according to Fischer test and comprised 2.2% in the Amulet and 2.3% in the Watchman group. The kind of device and the frequency of LAAC per study center had no influence on the success and complication rates. Device related thrombus could be revealed more frequently in the Watchman group (4.5%) than in the Amulet group (1.4%) but this difference is still not significant in Fisher test (p = 0.14). Same conclusion can be made about residual leakage 1.1% versus 0% [not significant in Fisher test (p = 0.26)]. Dual antiplatelet therapy followed the intervention in 64% and 22% of patients were discharged under a combination of an anticoagulant (VKA/DOAC/Heparin) and one antiplatelet agent. Conclusions: The ORIGINAL registry supports the thesis from large, randomized trials that LAAC can be performed with a very high procedural success rate in the everyday clinical routine irrespective of the used LAA device (Watchman or Amulet). The postprocedural antithrombotic strategy differs widely among the participating centers