A systematic literature review on the quality of moocs

This paper presents the findings from a systematic literature review on the quality of massive open online courses (MOOCs). The main research question was “How can the quality criteria for MOOCs identified in the analysed studies from the systematic literature review be best organ-ised in a categorisation scheme?” The systematic literature review was conducted using the PRISMA procedures. After conducting the screening and eligibility analysis according the pre-defined crite-ria, 103 studies were finally selected. The analysis was done in iterative cycles for continuous im-provements of the assignments and clustering of the quality criteria. The final version was validated in consensus through the categorisation and assignment of all 103 studies in a consistent way to four dimensions (pedagogical, organisational, technological, and social) and their sub-categories. This quality framework can be re-used in future MOOC research and the discussion of the analysed studies provides a current literature overview on the quality of MOOCs

Shedding Light on Team Adaptation: Does Experience Matter?

Investigating the team adaptation process in two laboratory experiments (N = 144 teams, n = 504 participants), we found no benefits for teams with team adaptation experience (vs. without) nor for teams with external team adaptation experience (vs. with internal experience). Collective experience under routine and nonroutine conditions seems to provide teams with the resources to adapt. We further found that executing the team adaptation process did not always lead to high team performance; different team performance requirements might explain these findings. We discuss how our experimental findings can extend our understanding of team adaptation toward new boundary conditions

The habitability of a stagnant-lid Earth

Plate tectonics is a fundamental component for the habitability of the Earth. Yet whether it is a recurrent feature of terrestrial bodies orbiting other stars or unique to the Earth is unknown. The stagnant lid may rather be the most common tectonic expression on such bodies. To understand whether a stagnant-lid planet can be habitable, i.e. host liquid water at its surface, we model the thermal evolution of the mantle, volcanic outgassing of H$_2$O and CO$_2$, and resulting climate of an Earth-like planet lacking plate tectonics. We used a 1D model of parameterized convection to simulate the evolution of melt generation and the build-up of an atmosphere of H$_2$O and CO$_2$ over 4.5 Gyr. We then employed a 1D radiative-convective atmosphere model to calculate the global mean atmospheric temperature and the boundaries of the habitable zone (HZ). The evolution of the interior is characterized by the initial production of a large amount of partial melt accompanied by a rapid outgassing of H$_2$O and CO$_2$. At 1 au, the obtained temperatures generally allow for liquid water on the surface nearly over the entire evolution. While the outer edge of the HZ is mostly influenced by the amount of outgassed CO$_2$, the inner edge presents a more complex behaviour that is dependent on the partial pressures of both gases. At 1 au, the stagnant-lid planet considered would be regarded as habitable. The width of the HZ at the end of the evolution, albeit influenced by the amount of outgassed CO$_2$, can vary in a non-monotonic way depending on the extent of the outgassed H$_2$O reservoir. Our results suggest that stagnant-lid planets can be habitable over geological timescales and that joint modelling of interior evolution, volcanic outgassing, and accompanying climate is necessary to robustly characterize planetary habitability

The extrasolar planet Gliese 581 d: a potentially habitable planet? (Corrigendum to arXiv:1009.5814)

We report here that the equation for H2O Rayleigh scattering was incorrectly stated in the original paper [arXiv:1009.5814]. Instead of a quadratic dependence on refractivity r, we accidentally quoted an r^4 dependence. Since the correct form of the equation was implemented into the model, scientific results are not affected.Comment: accepted to Astronomy&Astrophysic

The Quality Reference Framework for MOOC Design

This paper introduces "The Quality Reference Framework (QRF) for the Quality of MOOCs". It was developed by the European Alliance for the Quality of Massive Open Online Courses (MOOCs), called MOOQ that could involve in the QRF finalization more than 10,000 MOOC learners, designers, facilitators and providers. The QRF consists of three dimensions: Phases, Perspectives and Roles. It includes two quality instruments: the QRF Key Quality Criteria for MOOC experts and QRF Quality Checklist for MOOC beginners

Bestimmung der ernährungsphysiologischen Qualität von Öko-Produkten anhand des antioxidativen Potentials der Lebensmittel

Problemstellung: Die Diskussionen über sichere Lebensmittel (u.a. Rückstände von Pestiziden) im letzten Jahrzehnt hat das Verbraucherverhalten verändert. Viele Verbraucher bevorzugen ökologisch erzeugte Lebensmittel. Allerdings gibt es bis heute noch nicht ausreichende wissenschaftliche Daten dazu, ob ökologisch erzeugte Lebensmittel tatsächlich ernährungsphysiologisch hochwertiger sind als konventionell produzierte. Sekundären Pflanzenstoffen aus Obst und Gemüse (Carotinoiden, Polyphenole) kommt im Allgemeinen eine hohe gesundheitliche Bedeutung zu. Die in der Literatur beschriebenen protektiven Effekte auf entzündliche, atherosklerotische und tumorigene Prozesse werden u.a. auf ihr antioxidatives Potenzial zurückgeführt. Ziel der Studie war es daher zu untersuchen, ob sich der Gehalt an Carotinoiden und Polyphenolen und die antioxidative Kapazität in Lebensmitteln aus konventionellem und ökologischem Anbau unterscheidet. Darüber hinaus wurden drei humane Interventionsstudien durchgeführt, die klären sollten, ob die unterschiedlichen Anbauvarianten (ökologisch/konventionell) Einfluss auf die Bioverfügbarkeit der sekundären Pflanzenstoffe und den antioxidativen Status in vivo haben. Methodik: Im Rahmen des Projektes wurden Äpfel, Karotten und Weizenvollkorn der Erntejahre 2004, 2005 und 2006 aus kontrollierten Anbauversuchen untersucht. Die Gehalte an sekundären Pflanzenstoffen in vitro und in vivo wurden mittels HPLC/DAD/MS quantifiziert. Die antioxidativen Kapazitäten in vivo und in vitro wurden mit drei unterschiedlichen Testsystemen analysiert. Ergebnisse: Die Ergebnisse zeigen, dass die Anbauweise (ökologisch/konventionell) die Bildung von sekundären Pflanzenstoffen und das antioxidatives Potenzial in den untersuchten Lebensmitteln beeinflussen kann. Für die Öko-Produkte kann ein leicht höherer Gehalt und antioxidatives Potenzial bestimmt werden. In den durchgeführten Humanstudien, konnten keine Unterschiede in der Bioverfügbarkeit von Carotinoiden und Polyphenolen zwischen ökologisch und konventionell angebauten Äpfeln bzw. Karotten gezeigt werden. Schlussfolgerung: Die beobachteten Unterschiede im Gehalt an sekundären Pflanzenstoffen sowie im antioxidativen Potenzial zwischen den Anbauweisen sind klein und besitzen geringe ernährungsphysiologische Relevanz

Fostering quality in MOOCs: a european approach

Societal, educationaland personal changes have brought Open (Online) Education in the forefront of the global learning setting. One of the most significant challenges behind the EU Modernization Agenda is for education to respond to the characteristics of future students and to new needs in society. According to the Europe 2020 agenda, 40% of young people should complete higher education studies by 2020. The entire European university sector witnesses an increase of student numbers. Conventional learning methods are suboptimalsolutions for these massive student numbers. Thus, important questions and issues arise: How can we anticipate increasing student numbers combined with the likelihood of lower funding? How should we combine online and traditional formats to devise sustainable university business-models? In order to address these challenges Europe is investing in flexible educational solutions as this is embraced by the EC in its Open Educational Resource (OER) agenda. During the last years Massive Open Online Courses (MOOCs) became very popular: Since the year 2008, when the first MOOC was provided, the number of MOOCs is constantly increasing. The year 2012 was considered as the "Year of the MOOCs". However, MOOCs and OER are a good solution as long as they retain a certain level of quality. So far, experience and practice are leading to an increasing debate about their quality as an educational tool. The high drop-out rates of MOOCs that are typically measured in traditional distance education courses as well as in all formal education settings are discussed causing requests for rebooting MOOCs and the research on them and their quality. This article addresses the open issue of integration of quality approaches and mechanisms into the design of MOOCs through the development of a European MOOC Quality Reference Framework (QRF). The MOOC QRF provides a generic, organisation-wide system to help Higher Education Institutions and external stakeholders to design, develop, monitor, evaluate and improve the effectiveness of MOOCs along with the quality management practices. Based on flexible, configurable quality criteria and indicative descriptors, monitoring and reporting is adapted to organisational needs. The article presents the structure and quality dimensions of the MOOC QRF.It is based on the first international quality standard ISO/IEC 40180 and currently submitted to the European and international standardization committee (CEN TC 353 and ISO/IEC JTC1 SC36) for approval as first quality standard for MOOCs. The MOOC QRF is practical to encompass a wide range of approaches to quality assurance emphasizing that it is the quality of the outcomes that matters most in the design of MOOCs, thus leading to a new era of learning experiences in Europe.This article is supported by MOOQ, the European Alliance for Quality of Massive Open Online Courses (www.MOOC-quality.eu). The vision of MOOQ is to foster and improve quality in MOOCs leading to a new era of learning experiences. MOOQ is partly funded bythe European Commission under the following project number: 2015-1-NL01-KA203-008950.info:eu-repo/semantics/publishedVersio

Quantitative analysis of F-actin alterations in adherent human mesenchymal stem cells: Influence of slow-freezing and vitrification-based cryopreservation

Cryopreservation is an essential tool to meet the increasing demand for stem cells in medical applications. To ensure maintenance of cell function upon thawing, the preservation of the actin cytoskeleton is crucial, but so far there is little quantitative data on the influence of cryopreservation on cytoskeletal structures. For this reason, our study aims to quantitatively describe cryopreservation induced alterations to F-actin in adherent human mesenchymal stem cells, as a basic model for biomedical applications. Here we have characterised the actin cytoskeleton on single-cell level by calculating the circular standard deviation of filament orientation, F-actin content, and average filament length. Cryo-induced alterations of these parameters in identical cells pre and post cryopreservation provide the basis of our investigation. Differences between the impact of slow-freezing and vitrification are qualitatively analyzed and highlighted. Our analysis is supported by live cryo imaging of the actin cytoskeleton via two photon microscopy. We found similar actin alterations in slow-frozen and vitrified cells including buckling of actin filaments, reduction of F-actin content and filament shortening. These alterations indicate limited functionality of the respective cells. However, there are substantial differences in the frequency and time dependence of F-actin disruptions among the applied cryopreservation strategies; immediately after thawing, cytoskeletal structures show least disruption after slow freezing at a rate of 1°C/min. As post-thaw recovery progresses, the ratio of cells with actin disruptions increases, particularly in slow frozen cells. After 120 min of recovery the proportion of cells with an intact actin cytoskeleton is higher in vitrified than in slow frozen cells. Freezing at 10°C/min is associated with a high ratio of impaired cells throughout the post-thawing culture