3,746 research outputs found
Assessing hospitality industry employee perceptions of performance appraisals
Performance appraisals are prevalent in all credible hospitality organizations today (Capelli, 2016). After an extensive review of the literature, it is apparent that there is a considerable disconnect between the execution of the performance appraisal and the outcomes that a practitioner would expect. With the use of the implicit person theory (IPT) and the five-factor model (FFM), this study pursued a view of how the personality disposition of a manager may affect how a performance appraisal is perceived by subordinates suggesting that innately some managers are better suited to conduct performance appraisals. The aim of this research was to assess the relationship between the employeeās perceived fairness and effectiveness of a recently conducted performance appraisal and a managerās IPT disposition and FFM personality attributes.
Paired data were collected using four established instruments; two for the predictor variables and two for the dependent variables. IPT Disposition Survey (Dweck, 1999) and FFM Survey (Shafer, 1999) were used to collect predictor variable data. Justice Measures Survey (Colquit, 2001) and Effective Performance Evaluation Survey (Longenecker, Liverpool & Wilson, 1988) were used to collect dependent variable data. Additionally, demographic and descriptive data were obtained. A response rate of 77% (N=90) was received after hand-delivered survey packets were distributed to the manager and the employee samples. The participants were from 20 different hospitality organizations located in the northeast region of the United States; the sample was derived from hotels (7), restaurants (8) and private clubs (5).
Data were analyzed using descriptive statistics, Pearsonās Coefficient correlation analysis, Analysis of Variance (ANOVA), and regression analyses to test 15 hypothesis and to answer five research questions. Statistical significance was found between IPT incrementalism and perceived fairness [r (90) = .400, p\u3c.000]. Regression analysis revealed IPT incrementalism was statistically significant in predicting perceived fairness (F (1, 89) = 16.722, p \u3c.000]. Statistical significance was also present between IPT incrementalism and perceived effectiveness [r (90) = .435, p \u3c.000]. Regression analysis revealed IPT incrementalism was statistically significant in predicting perceived fairness [F (1, 89) = 20.501, p\u3c.000]. Among the manager sample, statistical significance was found in agreeableness of FFM related to effectiveness [F (1, 89) = 4.508, p = .037]. Lastly, sex and age were examined for differences in means. Among the employee sample, a t ā Test for equality of means revealed a statistically significant difference in means between sex and fairness [t (88) = -1.99, p = .049]. Practical and research implications are discussed; recommendations for further research and limitations regarding this present research are included.
Keywords: performance evaluation, manager personality, employee perceptions, fairness, effectivenes
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data. We thank John Low for carrying out the Cambridge Database survey.Peer reviewedPublisher PD
Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease
Copyright Ā© 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher PD
Crystal structures of four indole derivatives with a phenyl substituent at the 2-position and a carbonyl group at the 3-position : the C(6) N-HāÆO chain remains the same, but the weak reinforcing inter-actions are different
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data.Peer reviewedPublisher PD
Weak interactions in the crystal structures of two indole derivatives
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data.Peer reviewedPublisher PD
Different NāHĀ·Ā·Ā·Ļ interactions in two indole derivatives
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS dataPeer reviewedPublisher PD
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Draft Genome Sequences of 1,183 Salmonella Strains from the 100K Pathogen Genome Project.
Salmonella is a common food-associated bacterium that has substantial impact on worldwide human health and the global economy. This is the public release of 1,183 Salmonella draft genome sequences as part of the 100K Pathogen Genome Project. These isolates represent global genomic diversity in the Salmonella genus
Examining EdD Dissertations in Practice: The Carnegie Project on the Education Doctorate
In 2007, 25 colleges and schools of education (Phase I) came together under the aegis of the Carnegie Project on the Education Doctorate (CPED) to transform doctoral education for education practitioners. A challenging aspect of the reform of the educational doctorate is the role and design of the dissertation or Dissertation in Practice. In response to consortium concerns, members of the CPED Dissertation in Practice Awards Committee conducted this action research study to examine the format and design of Dissertations in Practice submitted by (re) designed programs. Data were gathered with an online survey, interviews, analyses of 25 Dissertations in Practice submitted in 2013 to the Committee. Results indicated few changes occurred in the final product, despite evidence of change in the Dissertation in Practice process. Findings contribute to debates about the distinctive nature of EdDs (and of professional doctorates generally) as distinct from PhDs, and how about the key criteria for demonstrating ānew knowledge to solve significant problems of practiceā are demonstrated through the dissertation submission
Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis
Background: The failure to mount an effective DNA damage response to repair UV induced cyclobutane pyrimidine dimers (CPDs) results in an increased propensity to develop cutaneous squamous cell carcinoma (cSCC). High-risk patient groups, such as organ transplant recipients (OTRs) frequently exhibit field cancerization at UV exposed body sites from which multiple human papillomavirus (HPV)-associated cSCCs develop rapidly, leading to profound morbidity and increased mortality. In vitro molecular evidence indicates that HPV of genus beta-papillomavirus (Ī²-PV) play an important role in accelerating the early stages of skin tumorigenesis. Methods: We investigated the effects of UV induced DNA damage in murine models of Ī²-PV E6 oncoprotein driven skin tumorigenesis by crossing K14-HPV8-E6wt mice (developing skin tumors after UV treatment) with K14-CPD-photolyase animals and by generating the K14-HPV8-E6-K136N mutant mouse strain. Thymine dimers (marker for CPDs) and Ī³H2AX (a marker for DNA double strand breaks) levels were determined in the murine skin and organotypic skin cultures of E6 expressing primary human keratinocytes after UV-irradiation by immunohistochemistry and in cell lines by In Cell Western blotting. Phosphorylation of ATR/Chk1 and ATM were assessed in cell lines and organotypic skin cultures by Western blots and immunohistochemistry. Results: Skin tumor development after UV-irradiation in K14-HPV8-E6wt mice could completely be blocked through expression of CPD-photolyase. Through quantification of thymine dimers after UV irradiation in cells expressing E6 proteins with point mutations at conserved residues we identified a critical lysine in the
Use of glycoprotein IIb/IIIa antagonists to prevent stent thrombosis in morphine-treated patients with ST-elevation myocardial infarction
Morphine can delay absorption of P2Y12-inhibitors in ST-elevation myocardial infarction (STEMI) patients, which has the potential to expose these patients to increased stent thrombosis risk after primary percutaneous coronary intervention (PPCI). Limited evidence exists for pharmacotherapeutic strategies aiming to mitigate this risk. We evaluated the impact of guideline-driven āroutineā glycoprotein IIb/IIIa antagonist (GPI) use in morphine-treated patients undergoing PPCI. A total of 3224 consecutive STEMI patients undergoing PPCI at a large tertiary cardiac center between 2012 and 2017 were evaluated. GPI use and outcomes before and after introduction of a local guideline were compared, and rates of definite stent thrombosis were identified at 24 h and 30 days. GPI use increased from 42.4% to 69.9% after the introduction of the new guideline. Stent thrombosis occurred in 1.3% (26/1947) pre-guideline and 0.6% (7/1244) post-guideline (P = .037). Of the 33 stent thrombosis cases, 90% (27/30) had received morphine, of whom 85.2% (23/27) had not received adjunctive GPI. Complete records for assessing 30-day bleeding rates were only available in 374 patients and, in this subset, there was no significant difference in rates of GUSTO moderate or severe bleeding before vs. after introduction of the local guideline (1.7% vs 2.8%; P = .47) although, in both cohorts combined, any GUSTO bleeding was observed more frequently in GPI-treated patients (21.8%) compared to those not receiving a GPI (10.0%; P = .002). In conclusion, routine GPI use in morphine-treated STEMI patients undergoing PPCI appears to protect against stent thrombosis. Large-scale studies are needed to establish the overall risk-benefit of GPI therapy in morphine-treated PPCI patients and to assess alternative strategies for preventing acute stent thrombosis in these patients
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