Sewer Science & Pound Seizure

Significant decisions are being made in the City and County of Los Angeles over a seemingly minor issue-pound seizure. Outwardly, the issue involves potentially inconvenienced animal research professionals versus angry citizens who do not want lost pets sold for research. However, on another level, this conflict has implications that reach the depths of irrationality. Far from fighting to promote the practice of pound seizure, scientists should be fighting to end it

Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports

Despite adequate evidence, including randomized controlled trials; hyperbaric oxygen is not yet recognized as efficacious for treating various forms of brain injury, specifically traumatic brain injury. Political-economic issues have kept this benign therapy from being widely adopted despite the lack of viable alternatives. Two football players with TBI/CTE are herewith shown to benefit from being treated with hyperbaric oxygen as documented by neurocognitive examinations and functional brain imaging, in one case treatment commenced decades after the brain injury. Perhaps the interest in HBOT by those participating in high-risk sports will help expand this orphan therapy into mainstream medicine

The application of cast SiC/Al to rotary engine components

A silicon carbide reinforced aluminum (SiC/Al) material fabricated by Dural Aluminum Composites Corporation was tested for various components of rotary engines. Properties investigated included hardness, high temperature strength, wear resistance, fatigue resistance, thermal conductivity, and expansion. SiC/Al appears to be a viable candidate for cast rotors, and may be applicable to other components, primarily housings

Perturbed Fourier uniqueness and interpolation results in higher dimensions

We obtain new Fourier interpolation and -uniqueness results in all dimensions, extending methods and results by the first author and M. Sousa, and by the second author. We show that the only Schwartz function which, together with its Fourier transform, vanishes on surfaces close to the origin-centered spheres whose radius are square roots of integers, is the zero function. In the radial case, these surfaces are spheres with perturbed radii, while in the non-radial case, they can be graphs of continuous functions over the sphere. As an application, we translate our perturbed Fourier uniqueness results to perturbed Heisenberg uniqueness for the hyperbola, using the interrelation between these fields introduced and studied by Bakan, Hedenmalm, Montes-Rodriguez, Radchenko and Viazovska.Comment: 22 page

Adsorption of phenol/tyrosol from aqueous solutions on macro-reticular aromatic and macro-porous polystyrene cross-linked with divinylbenzene polymeric resins

The current work aims at separating by adsorption of low-molecular-weight organic compounds in a nanofiltration concentrate of the olive mill wastewaters. The experimental investigations on adsorption of phenol/tyrosol in single and binary systems were conducted in batch mode by using the commercially available macroporous resins FPX66 and MN202. The structures of such resins were examined by FTIR before and after adsorption. The operating parameters affecting the adsorption process such as resin dosage, contact time, pH, and initial concentration of phenol/tyrosol were investigated. Fast phenol and tyrosol uptakes were observed for both resins. It can be attributed to their physical properties, for instance high specific area and microporous area. The adsorption selectivity of phenol is larger than tyrosol when using FPX66 resin, but smaller if MN202 resin is used. Acidic pH appeared to be always favourable for the adsorption. A synergetic effect between solutes was observed since adsorption of phenol and tyrosol in the binary systems was faster than the individual sorption of each solute. Five isotherms namely Langmuir, Freundlich, DubininRadushkevich, Temkin and Redlich-Peterson were selected to fit the obtained equilibrium experimental data. Finally, desorption of the examined compounds with ethanol (EtOH) allowed a maximum around 85 % of phenol, and equal to 94 % of tyrosol on FPX66 and MN202 resins

In vitro ion chelating, antioxidative mechanism of extracts from fruits and barks of tetrapleura tetraptera and their protective effects against fenton mediated toxicity of metal ions on liver homogenates

The aim of the present study was to investigate the antioxidant activity and protective potential of T. tetraptera extracts against ion toxicity. The antioxidant activity of the extracts was investigated spectrophotometrically against several radicals (1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS•), hydroxyl radical (HO•), and nitric oxide (NO•)), followed by the ferric reducing power, total phenols, flavonoid, and flavonol contents. The effects of the extracts on catalase (CAT), superoxide dismutase (SOD), and peroxidase activities were also determined using the standard methods as well as the polyphenol profile using HPLC. The results showed that the hydroethanolic extract of T. tetraptera (CFH) has the lowest ICvalue with the DPPH, ABTS, OH, and NO radicals. The same extract also exhibited the significantly higher level of total phenols (37.24 ± 2.00 CAE/g dried extract); flavonoids (11.36 ± 1.88 QE/g dried extract); and flavonols contents (3.95 ± 0.39 QE/g dried extract). The HPLC profile of T. tetraptera revealed that eugenol (958.81 ± 00 mg/g DW), quercetin (353.78 ± 00 mg/g DW), and rutin (210.54 ± 00 mg/g DW) were higher in the fruit than the bark extracts. In conclusion, extracts from T. tetraptera may act as a protector against oxidative mediated ion toxicity. © 2015 Bruno Moukette Moukette et al

Optical Diagnostics of Switching Arcs Near Current-zero: Speckle Imaging and Interferometry

Optical diagnostics can be used to obtain spatially resolved measurements of the density, temperature, conductivity, and electron density of circuit breaker arcs embedded in transonic flows; these can be used to validate the results of simulations, the accuracy of which can currently be assessed in only a limited way. We compare speckle imaging and an interferometric approach. Both use a pulsed nanosecond laser. The speckle imaging setup does not require a reference beam, but only yields information about the gradient of the refractive index. Its accuracy is sensitive to the alignment of the optical components. Interferometry directly yields high resolution images of the index of refraction, from which the density can be calculated using the Gladstone-Dale relation. By using two laser beams, interferometry provides spatially resolved information about the electron density. Such measurements are a significant step towards more accurate CFD models

When the Genome Plays Dice: Circumvention of the Spindle Assembly Checkpoint and Near-Random Chromosome Segregation in Multipolar Cancer Cell Mitoses

Background: Normal cell division is coordinated by a bipolar mitotic spindle, ensuring symmetrical segregation of chromosomes. Cancer cells, however, occasionally divide into three or more directions. Such multipolar mitoses have been proposed to generate genetic diversity and thereby contribute to clonal evolution. However, this notion has been little validated experimentally.Principal Findings: Chromosome segregation and DNA content in daughter cells from multipolar mitoses were assessed by multiphoton cross sectioning and fluorescence in situ hybridization in cancer cells and non-neoplastic transformed cells. The DNA distribution resulting from multipolar cell division was found to be highly variable, with frequent nullisomies in the daughter cells. Time-lapse imaging of H2B/GFP-labelled multipolar mitoses revealed that the time from the initiation of metaphase to the beginning of anaphase was prolonged and that the metaphase plates often switched polarity several times before metaphase-anaphase transition. The multipolar metaphase-anaphase transition was accompanied by a normal reduction of cellular cyclin B levels, but typically occurred before completion of the normal separase activity cycle. Centromeric AURKB and MAD2 foci were observed frequently to remain on the centromeres of multipolar ana-telophase chromosomes, indicating that multipolar mitoses were able to circumvent the spindle assembly checkpoint with some sister chromatids remaining unseparated after anaphase. Accordingly, scoring the distribution of individual chromosomes in multipolar daughter nuclei revealed a high frequency of nondisjunction events, resulting in a near-binomial allotment of sister chromatids to the daughter cells.Conclusion: The capability of multipolar mitoses to circumvent the spindle assembly checkpoint system typically results in a near-random distribution of chromosomes to daughter cells. Spindle multipolarity could thus be a highly efficient generator of genetically diverse minority clones in transformed cell populations