495 research outputs found

    Personality composition and performance in entrepreneurial teams:understanding the impact of stability and plasticity traits in a relative contribution model

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    Considering that personalities of entrepreneurs are diverse, we examine how the personality composition of entrepreneurial teams affects team performance. Given the specific challenges of the entrepreneurship setting, we suggest a new understanding of the team composition-team performance link by (1) taking a meta-perspective to personality that considers the stability vs. plasticity underlying the Big Five traits and by (2) applying a relative contribution (minimum/maximum) conceptualisation of team composition. We conduct a quantitative study with 104 entrepreneurial teams. Our findings indicate that high entrepreneurial team performance requires all team members to have minimum levels of stability-related traits (agreeableness, emotional stability, conscientiousness), but only one team member with high plasticity-related traits (openness, extraversion)

    CAEv–A program for computer aided evaluation

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    The evaluation of new reagents and instruments in clinical chemistry leads to complex studies with large volumes of data, which are difficult to handle. This paper presents the design and development of a program that supports an evaluator in the definition of a study, the generation of data structures, communication with the instrument (analyser), online and offline data capture and in the processing of the results. The program is called CAEv, and it runs on a standard PC under MS-DOS. Version 1 of the program was tested in a multicentre instrument evaluation. The concept and the necessary hardware and software are discussed. In addition, requirements for instrument/host communication are given. The application of the laboratory part of CAEv is described from the user's point of view. The design of the program allows users a high degree of flexibility in defining their own standards with regard to study protocol, and/or experiments, without loss of performance. CAEv's main advantages are a pre-programmed study protocol, easy handling of large volumes of data, an immediate validation of the experimental results and the statistical evaluation of the data

    Probabilistic Search for Object Segmentation and Recognition

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    The problem of searching for a model-based scene interpretation is analyzed within a probabilistic framework. Object models are formulated as generative models for range data of the scene. A new statistical criterion, the truncated object probability, is introduced to infer an optimal sequence of object hypotheses to be evaluated for their match to the data. The truncated probability is partly determined by prior knowledge of the objects and partly learned from data. Some experiments on sequence quality and object segmentation and recognition from stereo data are presented. The article recovers classic concepts from object recognition (grouping, geometric hashing, alignment) from the probabilistic perspective and adds insight into the optimal ordering of object hypotheses for evaluation. Moreover, it introduces point-relation densities, a key component of the truncated probability, as statistical models of local surface shape.Comment: 18 pages, 5 figure

    Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFβ1-signaling and increased Galectin-3 expression: A histological study on biopsies

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    Background Bisphosphonate associated osteonecrosis of the jaw (BRONJ) implies an impairment in oral hard- and soft tissue repair. An understanding of the signal transduction alterations involved can inform therapeutic strategies. Transforming growth factor β1 (TGFβ1) is a critical regulator of tissue repair; galectin-3 mediates tissue differentiation and specifically modulates periodontopathic bacterial infection. The aim of this study was to compare the expression of TGFβ1-related signaling molecules and Galectin-3 in BRONJ-affected and healthy mucosal tissues. To discriminate between BRONJ-specific impairments in TGFβ1 signaling and secondary inflammatory changes, the results were compared to the expression of TGFβ1 and Galectin-3 in mucosal tissues with osteoradionecrosis. Methods Oral mucosal tissue samples with histologically-confirmed BRONJ (n = 20), osteoradionecrosis (n = 20), and no lesions (normal, n = 20) were processed for immunohistochemistry. Automated staining with an alkaline phosphatase-anti-alkaline phosphatase kit was used to detect TGFβ1, Smad-2/3, Smad-7, and Galectin-3. We semiquantitatively assessed the ratio of stained cells/total number of cells (labeling index, Bonferroni-adjustment). Results TGFβ1 and Smad-2/3 were significantly decreased (p < 0.032 and p(0.028, respectively) in the BRONJ samples and significantly increased (p < 0.04 and p <0.043, respectively) in the osteoradionecrosis samples compared to normal tissue. Smad-7 was significantly increased (p < 0.031) in the BRONJ group and significantly decreased (p < 0.026) in the osteoradionecrosis group. Galectin-3 staining was significantly (p < 0.025) increased in both the BRONJ and the osteoradionecrosis (p < 0.038) groups compared to the normal tissue group. However, Galectin-3 expression was significantly higher in the BRONJ samples than in the osteoradionecrosis samples (p < 0.044). Conclusion Our results showed that disrupted TGFβ1 signaling was associated with delayed periodontal repair in BRONJ samples. The findings also indicated that impairments in TGFβ1-signaling were different in BRONJ compared to osteoradionecrosis. BRONJ appeared to be associated with increased terminal osseous differentiation and decreased soft tissue proliferation. The increase in Galectin-3 reflected the increase in osseous differentiation of mucoperiosteal progenitors, and this might explain the inflammatory anergy observed in BRONJ-affected soft tissues. The results substantiated the clinical success of treating BRONJ with sequestrectomy, followed by strict mucosa closure. BRONJ can be further elucidated by investigating the specific intraoral osteoimmunologic status

    A new test specimen for the determination of the field of view of small-area X-ray photoelectron spectrometers

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    Small-area/spot photoelectron spectroscopy (SAXPS) is a powerful tool for the investigation of small surface features like microstructures of electronic devices, sensors or other functional surfaces, and so forth. For evaluating the quality of such microstructures, it is often crucial to know whether a small signal in a spectrum is an unwanted contamination of the field of view (FoV), defined by the instrument settings, or it originated from outside. To address this issue, the d80/20 parameter of a line scan across a chemical edge is often used. However, the typical d80/20 parameter does not give information on contributions from the long tails of the X-ray beam intensity distribution or the electron-optical system as defined by apertures. In the VAMAS TWA2 A22 project “Applying planar, patterned, multi-metallic samples to assess the impact of analysis area in surface-chemical analysis,” new test specimen was developed and tested. The here presented testing material consists of a silicon wafer substrate with an Au-film and embedded Cr circular and square spots with decreasing dimensions from 200 μm down to 5 μm. The spot sizes are traceable to the length unit due to size measurements with a metrological SEM. For the evaluation of the FoV, we determined the Au4f intensities measured with the center of the FoV aligned with the center of the spot and normalized to the Au4f intensity determined on the Au-film. With this test specimen, it was possible to characterize, as an example, the FoV of a Kratos AXIS Ultra DLD XPS instrument

    Casimir force between integrable and chaotic pistons

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    We have computed numerically the Casimir force between two identical pistons inside a very long cylinder, considering different shapes for the pistons. The pistons can be considered as quantum billiards, whose spectrum determines the vacuum force. The smooth part of the spectrum fixes the force at short distances, and depends only on geometric quantities like the area or perimeter of the piston. However, correcting terms to the force, coming from the oscillating part of the spectrum which is related to the classical dynamics of the billiard, are qualitatively different for classically integrable or chaotic systems. We have performed a detailed numerical analysis of the corresponding Casimir force for pistons with regular and chaotic classical dynamics. For a family of stadium billiards, we have found that the correcting part of the Casimir force presents a sudden change in the transition from regular to chaotic geometries.Comment: 13 pages, 10 figure

    Summary of ISO/TC 201 International Standard ISO 18516:2019 Surface chemical analysis—Determination of lateral resolution and sharpness in beam-based methods with a range from nanometres to micrometres and its implementation for imaging laboratory X-ray photoelectron spectrometers (XPS)

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    ISO 18516:2019 Surface chemical analysis—Determination of lateral resolution and sharpness in beam-based methods with a range from nanometres to micrometres revises ISO 18516:2006 Surface chemical analysis—Auger electron spectroscopy and X-ray photoelectron spectroscopy—Determination of lateral resolution. It implements three different methods delivering parameters useful to express the lateral resolution: (1) the straight edge method, (2) the narrow line method and (3) the grating method. The theoretical background of these methods is introduced in ISO/TR 19319:2013 Surface chemical analysis—Fundamental approaches to determination of lateral resolution and sharpness in beam-based methods. The revised International Standard ISO 18516 delivers standardized procedures for the determination of the (1) effective lateral resolution by imaging of square-wave gratings, the (2) lateral resolution expressed as the parameter D12–88 characterizing the steepness of the sigmoidal edge spread function (ESF) determined by imaging a straight edge and (3) the lateral resolution expressed as the full width of half maximum of the line spread function (LSF), wLSF, determined by imaging a narrow line. The last method also delivers information on the shape of the LSF, which characterizes an individual imaging instrument. Finally, the implementation of all three standardized methods in the field of imaging laboratory X-ray photoelectron spectroscopy (XPS) is shortly presented. This part of the letter is based on the use of a new test sample developed at ETH Zurich, Switzerland. This test sample displays a micrometre scaled pattern motivated by the resolving power of recent imaging XPS instruments

    An exquisitely deep view of quenching galaxies through the gravitational lens: Stellar population, morphology, and ionized gas

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    This work presents an in-depth analysis of four gravitationally lensed red galaxies at z = 1.6-3.2. The sources are magnified by factors of 2.7-30 by foreground clusters, enabling spectral and morphological measurements that are otherwise challenging. Our sample extends below the characteristic mass of the stellar mass function and is thus more representative of the quiescent galaxy population at z > 1 than previous spectroscopic studies. We analyze deep VLT/X-SHOOTER spectra and multi-band Hubble Space Telescope photometry that cover the rest-frame UV-to-optical regime. The entire sample resembles stellar disks as inferred from lensing-reconstructed images. Through stellar population synthesis analysis we infer that the targets are young (median age = 0.1-1.2 Gyr) and formed 80% of their stellar masses within 0.07-0.47 Gyr. Mg II λλ2796,2803\lambda\lambda 2796,2803 absorption is detected across the sample. Blue-shifted absorption and/or redshifted emission of Mg II is found in the two youngest sources, indicative of a galactic-scale outflow of warm (T104T\sim10^{4} K) gas. The [O III] λ5007\lambda5007 luminosity is higher for the two young sources (median age less than 0.4 Gyr) than the two older ones, perhaps suggesting a decline in nuclear activity as quenching proceeds. Despite high-velocity (v1500v\approx1500 km s1^{-1}) galactic-scale outflows seen in the most recently quenched galaxies, warm gas is still present to some extent long after quenching. Altogether our results indicate that star formation quenching at high redshift must have been a rapid process (< 1 Gyr) that does not synchronize with bulge formation or complete gas removal. Substantial bulge growth is required if they are to evolve into the metal-rich cores of present-day slow-rotators.Comment: Accepted for publication in the Astrophysical Journal. 37 pages, 20 figures, 10 table

    Periodic Orbits in Polygonal Billiards

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    We review some properties of periodic orbit families in polygonal billiards and discuss in particular a sum rule that they obey. In addition, we provide algorithms to determine periodic orbit families and present numerical results that shed new light on the proliferation law and its variation with the genus of the invariant surface. Finally, we deal with correlations in the length spectrum and find that long orbits display Poisson fluctuations.Comment: 30 pages (Latex) including 11 figure
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