TIGER Capacity Building Facility - Phase 1, lessons learnt

The TIGER Capacity Building Facility focused on closing the technological gap between the users and the earth observation community within the TIGER programme. Thirteen projects participated in different aspects of the capacity building facility: 1. - Basic education, provided via distance learning. 2. - Tailored short courses, selected according to the research interest and technical background of the participants. 3. - Research topic oriented supervision, provided by specialists of the research fields of the participants. 4. - Advanced short courses focusing on selected earth observation techniques. Distance education turned to be efficient and cost effective in the programme - but only for those, who followed the courses completely. There was a relatively large percentage that could not complete the studies. The second and the third type of education were carried out in ITC, in the Netherlands. The participants evaluated the courses and the supervision very effective and adequate. Nevertheless, the follow-up was not always possible. Two advanced short courses were held in Africa (Cape Town and Nairobi). One of them addressed the 'scientific elite' of the EO community, whilst the second focused on the users of this technology

Clinically insignificant association between anterior knee pain and patellofemoral lesions which are found incidentally.

Patellofemoral chondral lesions are frequently identified incidentally during the arthroscopic treatment of other knee pathologies. A role has been described for arthroscopic debridement of such lesions when symptoms are known to originate from pathology of the patellofemoral joint. However, it remains unclear how to manage lesions which are found incidentally whilst tackling other pathologies. The purpose of this study was to establish the strength of association between anterior knee pain and patellofemoral lesions identified incidentally in a typical arthroscopic population. A consecutive series of patients undergoing arthroscopy for a range of standard indications formed the basis of this cross section study. We excluded those with patellofemoral conditions in order to identify patellofemoral lesions which were solely incidental. Pre-operative assessments were performed on 64 patients, where anterior knee pain was sought by three methods: an annotated photographic knee pain map (PKPM), patient indication with one finger and by palpated tenderness. A single surgeon, who was blinded to previous recordings, performed standard arthroscopies and recorded patellofemoral lesions. Statistical correlations were performed to identify the association magnitude. Associations were identified between incidental patellofemoral lesions and tenderness palpated on the medial patella (P=0.007, χ2=0.32) and the quadriceps tendon (P=0.029, χ2=0.26), but these associations were at best fair, which could be interpreted as clinically insignificant. In which case incidental patellofemoral lesions are not necessarily associated with anterior knee pain, we suggest that they could be left alone. This recommendation is only applicable to patellofemoral lesions which are found incidentally whilst addressing other pathology

A Review Of Business Cycle Theory And Forecast Of The Current Business Cycle

As the business cycle fluctuates, the U.S. economy may face increased unemployment in the case of an economic downturn or increased inflation in the stage of an expansion. Therefore, the study of business cycles is important in determining the current and future condition of the economy as a whole. This study seeks to expand the current body of knowledge of the business cycle by combining the history of economic theory of “Veblen”, “Marx”, “Schumpterer”, “Friedman”, “Keynes”, “Minsky”, and “Sherman” with the diffusion index popularized by “Valentine and Dauten” (1983). The purpose of this study are two-folds: first is to review the theoretical framework of the history of economic thoughts of business cycle and the methodology of diffusion index; second is to use these economic theories and the technique of diffusion index  to forecast the strength and direction of the business cycle of the US economy. The results of this study indicate that it is possible to derive an accurate forecast of the strength and direction of the business cycle by combining economic theories and the technique of diffusion index. &nbsp

An Idealized Model of Weddell Gyre Export Variability

Recent observations suggest that the export of Antarctic Bottom Water (AABW) from the Weddell Sea has a seasonal cycle in its temperature and salinity that is correlated with annual wind stress variations. This variability has been attributed to annual vertical excursions of the isopycnals in the Weddell Gyre, modifying the water properties at the depth of the Orkney Passage. Recent studies attribute these variations to locally wind-driven barotropic dynamics in the northern Weddell Sea boundary current. This paper explores an alternative mechanism in which the isopycnals respond directly to surface Ekman pumping, which is coupled to rapidly responding mesoscale eddy buoyancy fluxes near the gyre boundary. A conceptual model of the interface that separates Weddell Sea Deep Water from Circumpolar Deep Water is described in which the bounding isopycnal responds to a seasonal oscillation in the surface wind stress. Different parameterizations of the mesoscale eddy diffusivity are tested. The model accurately predicts the observed phases of the temperature and salinity variability in relationship to the surface wind stress. The model, despite its heavy idealization, also accounts for more than 50% of the observed oscillation amplitude, which depends on the strength of the seasonal wind variability and the parameterized eddy diffusivity. These results highlight the importance of mesoscale eddies in modulating the export of AABW in narrow boundary layers around the Antarctic margins

Ocean Convective Available Potential Energy. Part II: Energetics of Thermobaric Convection and Thermobaric Cabbeling

The energetics of thermobaricity- and cabbeling-powered deep convection occurring in oceans with cold freshwater overlying warm salty water are investigated here. These quasi-two-layer profiles are widely observed in wintertime polar oceans. The key diagnostic is the ocean convective available potential energy (OCAPE), a concept introduced in a companion piece to this paper (Part I). For an isolated ocean column, OCAPE arises from thermobaricity and is the maximum potential energy (PE) that can be converted into kinetic energy (KE) under adiabatic vertical parcel rearrangements. This study explores the KE budget of convection using two-dimensional numerical simulations and analytical estimates. The authors find that OCAPE is a principal source for KE. However, the complete conversion of OCAPE to KE is inhibited by diabatic processes. Further, this study finds that diabatic processes produce three other distinct contributions to the KE budget: (i) a sink of KE due to the reduction of stratification by vertical mixing, which raises water column’s center of mass and thus acts to convert KE to PE; (ii) a source of KE due to cabbeling-induced shrinking of the water column’s volume when water masses with different temperatures are mixed, which lowers the water column’s center of mass and thus acts to convert PE into KE; and (iii) a reduced production of KE due to diabatic energy conversion of the KE convertible part of the PE to the KE inconvertible part of the PE. Under some simplifying assumptions, the authors also propose a theory to estimate the maximum depth of convection from an energetic perspective. This study provides a potential basis for improving the convection parameterization in ocean models

Ocean Convective Available Potential Energy. Part I: Concept and Calculation

Thermobaric convection (type II convection) and thermobaric cabbeling (type III convection) might substantially contribute to vertical mixing, vertical heat transport, and deep-water formation in the World Ocean. However, the extent of this contribution remains poorly constrained. The concept of ocean convective available potential energy (OCAPE), the thermobaric energy source for type II and type III convection, is introduced to improve the diagnosis and prediction of these convection events. OCAPE is analogous to atmospheric CAPE, which is a key energy source for atmospheric moist convection and has long been used to forecast moist convection. OCAPE is the potential energy (PE) stored in an ocean column arising from thermobaricity, defined as the difference between the PE of the ocean column and its minimum possible PE under adiabatic vertical parcel rearrangements. An ocean column may be stably stratified and still have nonzero OCAPE. The authors present an efficient strategy for computing OCAPE accurately for any given column of seawater. They further derive analytical expressions for OCAPE for approximately two-layer ocean columns that are widely observed in polar oceans. This elucidates the dependence of OCAPE on key physical parameters. Hydrographic profiles from the winter Weddell Sea are shown to contain OCAPE (0.001–0.01 J kg^(−1)), and scaling analysis suggests that OCAPE may be substantially enhanced by wintertime surface buoyancy loss. The release of this OCAPE may substantially contribute to the kinetic energy of deep convection in polar oceans

Validation of an electrogoniometry system as a measure of knee kinematics during activities of daily living

Purpose: The increasing use of electrogoniometry (ELG) in clinical research requires the validation of different instrumentation. The purpose of this investigation was to examine the concurrent validity of an ELG system during activities of daily living. Methods: Ten asymptomatic participants gave informed consent to participate. A Biometrics SG150 electrogoniometer was directly compared to a 12 camera three dimensional motion analysis system during walking, stair ascent, stair descent, sit to stand, and stand to sit activities for the measurement of the right knee angle. Analysis of validity was undertaken by linear regression. Standard error of estimate (SEE), standardised SEE (SSEE), and Pearson’s correlation coefficient r were computed for paired trials between systems for each functional activity. Results: The 95% confidence interval of SEE was reasonable between systems across walking (LCI = 2.43 °; UCI = 2.91 °), stair ascent (LCI = 2.09 °; UCI = 2.42 °), stair descent (LCI = 1.79 °; UCI = 2.10 °), sit to stand (LCI = 1.22 °; UCI = 1.41 °), and stand to sit (LCI = 1.17 °; UCI = 1.34 °). Pearson’s correlation coefficient r across walking (LCI = 0.983; UCI = 0.990), stair ascent (LCI = 0.995; UCI = 0.997), stair descent (LCI = 0.995; UCI = 0.997), sit to stand (LCI = 0.998; UCI = 0.999), and stand to sit (LCI = 0.996; UCI = 0.997) was indicative of a strong linear relationship between systems. Conclusion: ELG is a valid method of measuring the knee angle during activities representative of daily living. The range is within that suggested to be acceptable for the clinical evaluation of patients with musculoskeletal conditions

Modeling Collisional Cascades In Debris Disks: The Numerical Method

We develop a new numerical algorithm to model collisional cascades in debris disks. Because of the large dynamical range in particle masses, we solve the integro-differential equations describing erosive and catastrophic collisions in a particle-in-a-box approach, while treating the orbital dynamics of the particles in an approximate fashion. We employ a new scheme for describing erosive (cratering) collisions that yields a continuous set of outcomes as a function of colliding masses. We demonstrate the stability and convergence characteristics of our algorithm and compare it with other treatments. We show that incorporating the effects of erosive collisions results in a decay of the particle distribution that is significantly faster than with purely catastrophic collisions.Comment: 24 pages, 20 figues, Published in Ap

Comparison of Body Size, Morphomics, and Kidney Function as Covariates of High‐Dose Methotrexate Clearance in Obese Adults with Primary Central Nervous System Lymphoma

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154919/1/phar2379.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154919/2/phar2379_am.pd