9,675 research outputs found
The Ultimate Fate of Supercooled Liquids
In recent years it has become widely accepted that a dynamical length scale
{\xi}_{\alpha} plays an important role in supercooled liquids near the glass
transition. We examine the implications of the interplay between the growing
{\xi}_{\alpha} and the size of the crystal nucleus, {\xi}_M, which shrinks on
cooling. We argue that at low temperatures where {\xi}_{\alpha} > {\xi}_M a new
crystallization mechanism emerges enabling rapid development of a large scale
web of sparsely connected crystallinity. Though we predict this web percolates
the system at too low a temperature to be easily seen in the laboratory, there
are noticeable residual effects near the glass transition that can account for
several previously observed unexplained phenomena of deeply supercooled liquids
including Fischer clusters, and anomalous crystal growth near T_g
Commensurate Scale Relations in Quantum Chromodynamics
We use the BLM method to show that perturbatively-calculable observables in
QCD can be related to each other without renormalization scale or scheme
ambiguity. We define and study the commensurate scale relations. We show that
the commensurate scales satisfy the renormalization group transitivity rule
which ensures that predictions in PQCD are independent of the choice of an
intermediate renormalization scheme. We generalize the BLM procedure to higher
order. The application of this procedure to relate known physical observables
in QCD gives surprisingly simple results. In particular, the annihilation ratio
and the Bjorken sum rule for polarized electroproduction are
related through simple coefficients, which reinforces the idea of a hidden
symmetry between these two observables.Comment: 35 pages (RevTeX), one PostScript figure included at the end.
SLAC-PUB-6481, UMD Preprint #94-13
Predicting protein decomposition: the case of aspartic-acid racemization kinetics
The increase in proportion of the non-biological (D-) isomer of aspartic acid (Asp) relative to the L- isomer has been widely used in archaeology and geochemistry as a tool for dating. The method has proved controversial, particularly when used for bones. The non-linear kinetics of Asp racemization have prompted a number of suggestions as to the underlying mechanism(s) and have led to the use of mathe- matical transformations which linearize the increase in D-Asp with respect to time. Using one example, a suggestion that the initial rapid phase of Asp racemization is due to a contribution from asparagine (Asn), we demonstrate how a simple model of the degradation and racemization of Asn can be used to predict the observed kinetics. A more complex model of peptide bound Asx (Asn+Asp) racemization, which occurs via the formation of a cyclic succinimide (Asu), can be used to correctly predict Asx racemi- zation kinetics in proteins at high temperatures (95-140 °C). The model fails to predict racemization kinetics in dentine collagen at 37 °C. The reason for this is that Asu formation is highly conformation dependent and is predicted to occur extremely slowly in triple helical collagen. As conformation strongly in£uences the rate of Asu formation and hence Asx racemization, the use of extrapolation from high temperatures to estimate racemization kinetics of Asx in proteins below their denaturation temperature is called into question. In the case of archaeological bone, we argue that the D:L ratio of Asx re£ects the proportion of non- helical to helical collagen, overlain by the e¡ects of leaching of more soluble (and conformationally unconstrained) peptides. Thus, racemization kinetics in bone are potentially unpredictable, and the proposed use of Asx racemization to estimate the extent of DNA depurination in archaeological bones is challenged
Scale-independent mixing angles
A radiatively-corrected mixing angle has to be independent of the choice of
renormalization scale to be a physical observable. At one-loop in MS-bar, this
only occurs for a particular value, p*, of the external momentum in the
two-point functions used to define the mixing angle: p*^2=(M1^2+M2^2)/2, where
M1, M2 are the physical masses of the two mixed particles. We examine two
important applications of this to the Minimal Supersymmetric Standard Model:
the mixing angle for a) neutral Higgs bosons and b) stops. We find that this
choice of external momentum improves the scale independence (and therefore
provides a more reliable determination) of these mixing angles.Comment: 14 pages, 11 ps figures Version to appear in PR
A multiwavelength approach to the SFR estimation in galaxies at intermediate redshifts
We use a sample of 7 starburst galaxies at intermediate redshifts (z ~ 0.4
and z ~ 0.8) with observations ranging from the observed ultraviolet to 1.4
GHz, to compare the star formation rate (SFR) estimators which are used in the
different wavelength regimes. We find that extinction corrected Halpha
underestimates the SFR, and the degree of this underestimation increases with
the infrared luminosity of the galaxies. Galaxies with very different levels of
dust extinction as measured with SFR(IR)/SFR(Halpha, uncorrected for
extinction) present a similar attenuation A[Halpha], as if the Balmer lines
probed a different region of the galaxy than the one responsible for the bulk
of the IR luminosity for large SFRs. In addition, SFR estimates derived from
[OII]3727 match very well those inferred from Halpha after applying the
metallicity correction derived from local galaxies. SFRs estimated from the UV
luminosities show a dichotomic behavior, similar to that previously reported by
other authors in galaxies at z <~ 0.4. Here we extend this result up to z ~
0.8. Finally, one of the studied objects is a luminous compact galaxy (LCG)
that may be suffering similar dust-enshrouded star formation episodes. These
results highlight the relevance of quantifying the actual L(IR) of LCGs, as
well as that of a much larger and generic sample of luminous infrared galaxies,
which will be possible after the launch of SIRTF.Comment: Accepted for publication in The Astrophysical Journa
Why Pad\'e Approximants reduce the Renormalization-Scale dependence in QFT?
We prove that in the limit where the beta function is dominated by the 1-loop
contribution (``large beta_0 limit'') diagonal Pad\'e Approximants (PA's) of
perturbative series become exactly renormalization scale (RS) independent. This
symmetry suggest that diagonal PA's are resumming correctly contributions from
higher order diagrams that are responsible for the renormalization of the
coupling-constant. Non-diagonal PA's are not exactly invariant, but generally
reduce the RS dependence as compared to partial-sums. In physical cases,
higher-order corrections in the beta function break the symmetry softly,
introducing a small scale and scheme dependence. We also compare the Pad\'e
resummation with the BLM method. We find that in the large-N_f limit using the
BLM scale is identical to resumming the series by a non-diagonal PA.Comment: 25 pages, LateX. Replaced so that the figures would fit into the page
siz
Colorectal cancer genomics: evidence for multiple genotypes which influence survival
Colorectal cancer (CRC) is a leading cause of cancer death and the mechanism for variable outcome in this disease is not yet fully understood. It is hypothesized that differences in the genetic make-up of tumours may be partially responsible for the differences observed in survival among same staged individuals for this disease. In this study the tumour genomes of 29 consecutive patients undergoing surgery for Dukes' C CRC were assessed by comparative genomic hybridization (CGH). In addition, the CGH profiles from the tumours were compared with those from eight colorectal cell lines. Great variation in genetic grade (all detectable aberrations i.e., loss + gain) was observed in 29 Dukes' C colorectal tumours by CGH (median four aberrations per tumour, range 0–20). Gain was found in 76% and loss in 41% of tumours. The most frequently observed regions of gain were 13q (27.6%), 20q (27.6%), 7p (24.1%), 8q (24.1%), and 1q (20.7%) and loss were 18q (31%), 4q (20.7%), 17p (20.7%), 18p (20.7%), and 15q (20.1%). None of these specific genomic aberrations were associated with patient survival. However, patients with more than two aberrations had a better survival than patients with fewer regions of loss and gain (P = 0.02). CRC cell lines had similar regions of loss or gain as the tumours. However, the frequency of genomic aberrations was much greater in the CRC cell lines. Although genomic change in CRC is relevant to the survival of patients with Dukes' C CRC, careful analysis is required to identify cell lines which are representative models of CRC genomics.© 2001 Cancer Research Campaign http://www.bjcancer.co
HST PanCET program: A Cloudy Atmosphere for the promising JWST target WASP-101b
We present results from the first observations of the Hubble Space Telescope
(HST) Panchromatic Comparative Exoplanet Treasury (PanCET) program for
WASP-101b, a highly inflated hot Jupiter and one of the community targets
proposed for the James Webb Space Telescope (JWST) Early Release Science (ERS)
program. From a single HST Wide Field Camera 3 (WFC3) observation, we find that
the near-infrared transmission spectrum of WASP-101b contains no significant
HO absorption features and we rule out a clear atmosphere at 13{\sigma}.
Therefore, WASP-101b is not an optimum target for a JWST ERS program aimed at
observing strong molecular transmission features. We compare WASP-101b to the
well studied and nearly identical hot Jupiter WASP-31b. These twin planets show
similar temperature-pressure profiles and atmospheric features in the
near-infrared. We suggest exoplanets in the same parameter space as WASP-101b
and WASP-31b will also exhibit cloudy transmission spectral features. For
future HST exoplanet studies, our analysis also suggests that a lower count
limit needs to be exceeded per pixel on the detector in order to avoid unwanted
instrumental systematics.Comment: 7 pages, 4 figures, 1 table, Accepted to ApJ
Complete next-to-leading order perturbative QCD prediction for the pion electromagnetic form factor
We present the results of a complete leading-twist next-to-leading order
(NLO) QCD analysis of the spacelike pion electromagnetic form factor at large
momentum transfer Q. We have studied their dependence on the form of the pion
distribution amplitude. For a given distribution amplitude, we have examined
the sensitivity of the predictions to the choice of the renormalization and
factorization scales. Theoretical uncertainty of the LO results related to the
renormalization scale ambiguity has been significantly reduced by including the
NLO corrections. Adopting the criteria according to which a NLO prediction is
considered reliable if, both, the ratio of the NLO to LO contributions and the
strong coupling constant are reasonably small, we find that reliable
perturbative predictions for the pion electromagnetic form factor with all
distribution amplitudes considered can already be made at a momentum transfer
Q<10 GeV, with corrections to the LO results being typically of the order of ~
20%. To check our predictions and to discriminate between the distribution
amplitudes, it is necessary to obtain experimental data extending to higher
values of Q.Comment: 39 pages, RevTex, 17 figures included; revised version (an error in
the analytical expression for T_H corrected, numerical results correspondigly
modified; presentation of the results modified to some extent and some points
discussed in more detail after referees reports
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