Assessing the contribution of shallow and deep knowledge sources for word sense disambiguation

Corpus-based techniques have proved to be very beneficial in the development of efficient and accurate approaches to word sense disambiguation (WSD) despite the fact that they generally represent relatively shallow knowledge. It has always been thought, however, that WSD could also benefit from deeper knowledge sources. We describe a novel approach to WSD using inductive logic programming to learn theories from first-order logic representations that allows corpus-based evidence to be combined with any kind of background knowledge. This approach has been shown to be effective over several disambiguation tasks using a combination of deep and shallow knowledge sources. Is it important to understand the contribution of the various knowledge sources used in such a system. This paper investigates the contribution of nine knowledge sources to the performance of the disambiguation models produced for the SemEval-2007 English lexical sample task. The outcome of this analysis will assist future work on WSD in concentrating on the most useful knowledge sources

Mouse tafazzin is required for male germ cell meiosis and spermatogenesis

Barth syndrome is an X-linked mitochondrial disease, symptoms of which include neutropenia and cardiac myopathy. These symptoms are the most significant clinical consequences of a disease, which is increasingly recognised to have a variable presentation. Mutation in the Taz gene in Xq28 is thought to be responsible for the condition, by altering mitochondrial lipid content and mitochondrial function. Male chimeras carrying a targeted mutation of Taz on their X-chromosome were infertile. Testes from the Taz knockout chimeras were smaller than their control counterparts and this was associated with a disruption of the progression of spermatocytes through meiosis to spermiogenesis. Taz knockout ES cells also showed a defect when differentiated to germ cells in vitro. Mutant spermatocytes failed to progress past the pachytene stage of meiosis and had higher levels of DNA double strand damage and increased levels of endogenous retrotransposon activity. Altogether these data revealed a novel role for Taz in helping to maintain genome integrity in meiosis and facilitating germ cell differentiation. We have unravelled a novel function for the Taz protein, which should contribute to an understanding of how a disruption of the Taz gene results in the complex symptoms underlying Barth Syndrome

Influence of convective transport on tropospheric ozone and its precursors in a chemistry-climate model

The impact of convection on tropospheric O₃ and its precursors has been examined in a coupled chemistry-climate model. There are two ways that convection affects O₃. First, convection affects O₃ by vertical mixing of O₃ itself. Convection lifts lower tropospheric air to regions where the O₃ lifetime is longer, whilst mass-balance subsidence mixes O₃-rich upper tropospheric (UT) air downwards to regions where the O₃ lifetime is shorter. This tends to decrease UT O₃ and the overall tropospheric column of O₃. Secondly, convection affects O₃ by vertical mixing of O₃ precursors. This affects O₃ chemical production and destruction. Convection transports isoprene and its degradation products to the UT where they interact with lightning NO_x to produce PAN, at the expense of NO_x. In our model, we find that convection reduces UT NO_x through this mechanism; convective down-mixing also flattens our imposed profile of lightning emissions, further reducing UT NO_x. Over tropical land, which has large lightning NO_x emissions in the UT, we find convective lofting of NO_x from surface sources appears relatively unimportant. Despite UT NO_x decreases, UT O₃ production increases as a result of UT HO_x increases driven by isoprene oxidation chemistry. However, UT O₃ tends to decrease, as the effect of convective overturning of O₃ itself dominates over changes in O₃ chemistry. Convective transport also reduces UT O₃ in the mid-latitudes resulting in a 13% decrease in the global tropospheric O₃ burden. These results contrast with an earlier study that uses a model of similar chemical complexity. Differences in convection schemes as well as chemistry schemes – in particular isoprene-driven changes are the most likely causes of such discrepancies. Further modelling studies are needed to constrain this uncertainty range

Chemical chronology of the Southern Coalsack

We demonstrate how the observed H2O ice column densities toward three dense globules in the Southern Coalsack could be used to constrain the ages of these sources. We derive ages of ~10^5 yr, in agreement with dynamical studies of these objects. We have modelled the chemical evolution of the globules, and show how the molecular abundances are controlled by both the gas density and the initial chemical conditions as the globules formed. Based on our derived ages, we predict the column densities of several species of interest. These predictions should be straightforward to test by performing molecular line observationsComment: 10 pages, 4 figures, in press at MNRA

The unrestricted Skyrme-tensor time-dependent Hartree-Fock and its application to the nuclear response from spherical to triaxial nuclei

The nuclear time-dependent Hartree-Fock model formulated in the three-dimensional space,based on the full Skyrme energy density functional and complemented with the tensor force,is presented for the first time. Full self-consistency is achieved by the model. The application to the isovector giant dipole resonance is discussed in the linear limit, ranging from spherical nuclei (16O, 120Sn) to systems displaying axial or triaxial deformation (24Mg, 28Si, 178Os, 190W, 238U). Particular attention is paid to the spin-dependent terms from the central sector of the functional, recently included together with the tensor. They turn out to be capable of producing a qualitative change on the strength distribution in this channel. The effect on the deformation properties is also discussed. The quantitative effects on the linear response are small and, overall, the giant dipole energy remains unaffected. Calculations are compared to predictions from the (quasi)-particle random phase approximation and experimental data where available, finding good agreement