153 research outputs found

    A Geographic Interpretation of the Agricultural Regions of Ohio

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    The purpose of this thesis is to divide the state of Ohio into agricultural regions, and, so delimited, to describe and interpret these regions in a geographic manner. The basis of division is the use of the land for varying agricultural purposes. These variables are expressed my means of isopleth maps showing acreage percentages of land use. Factors of the natural environment, such as soil, bedrock, climate, topography, and drainage, aid in the interpretation of these regions

    A Geographic Interpretation of the Agricultural Regions of Ohio

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    The purpose of this thesis is to divide the state of Ohio into agricultural regions, and, so delimited, to describe and interpret these regions in a geographic manner. The basis of division is the use of the land for varying agricultural purposes. These variables are expressed my means of isopleth maps showing acreage percentages of land use. Factors of the natural environment, such as soil, bedrock, climate, topography, and drainage, aid in the interpretation of these regions

    Models of Adult Safeguarding in England: Findings from a Study of Costs and Referral Outcomes

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    Adult safeguarding is the subject of increasing attention in England and internationally. This article draws on research which developed a typology of ‘models of safeguarding’. ‘Models’ refer to different ways local authorities in England organise adult safeguarding (about which there is little evidence) rather than ‘model’ approaches to be emulated. The four models identified were: Dispersed-Generic (safeguarding work undertaken by operational teams); Dispersed-Specialist (safeguarding work undertaken partly by specialist social workers located in operational teams); Partially Centralised-Specialist (some safeguarding work undertaken by a central specialist safeguarding team); and Fully-Centralised-Specialist (all safeguarding work undertaken by a specialist safeguarding team). We explored associations between these models and other important variables (numbers of referrals, kinds of alleged abuse and characteristics of adults at risk) and outcomes. The article reports secondary analysis of English local authority safeguarding referral data and on the possible different costs of different models. Dispersed-Specialist sites appeared to have a higher rate of substantiating alleged abuse compared with other models. Statistical correlations were found with types of victim profiles and the perpetrator/victim relationship. It may be that decisions about local organisation of safeguarding are more affected by local organisational contexts than local authority model

    Outlook and appraisal [November 1985]

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    The Scottish economy, like that of the UK as a whole, looks set to experience a substantial shift in the relative importance of the factors determining growth in the coming year. As discussed elsewhere in the Commentary (see British Economy), growth in the recent past has been driven mainly by the expansion of investment and exports. With the interrelated factors of sterling's strength and continuing high real UK interest rates operating against a background of some deceleration in the growth of world trade, the prospect is that these influences will be largely replaced by the re-emergence of consumers' expenditure as the principal determinant of growth

    The Scottish economy [November 1985]

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    With the inauguration of the quarterly Scottish Business Survey (SBS) in September 1984 there are now two regular up-to-date indicators of trends in the Scottish industrial sector. The combination of the new survey and the long-standing CBI Industrial Trends Survey provides a comprehensive assessment of trends in Scottish industry

    The British economy [November 1985]

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    In his November Statement the Chancellor of the Exchequer has forecast continuing expansion of the economy during 1986. The recent growth of exports and investment is not expected to be maintained but consumer spending, boosted by higher real earnings and tax cuts in the Spring Budget, will rise

    The world economy [November 1985]

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    After the marked deceleration in the first half of the year US growth shows signs of picking up in the latter part of 1985. However, the impetus to world trade and global expansion derived from the rapid period of US growth in late 1983 and early 1984 has now largely waned. Although European countries and Japan are set to continue their recent expansion, it is unlikely that their growth will offset the impact on the world economy of a slower rate of US growth

    The Vehicle, Spring 2001

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    Vol. 42, No. 2 Table of Contents To Dream Without CeasingElizabeth Dedmanpage 4-5 Honoring Commandos at Spean BridgeKat Stevenspage 6 The Girl I NamelyKevin Manuspage 7 AbsolutionMike Mauritzenpage 8 Summertime SuperheroesChris Ptasnikpage 9 Flower at GlencoeKat Stevenspage 10 AddictionAdam Funkpage 11 Cornfield in JanuaryRobert Prattepage 12 MelancholyOona Margaret Burkepage 13 In PicturesAmanda McKaypage 14 Words to a Silent FilmBrianne Bolinpage 15 ManagerRobert Prattepage 16 The WellJanet Windegathpage 17 A Meal at the Personal Growth CafeAshley Kieferpage 18 Castlegate Evening at AberdeenKat Stevenspage 19 What We AreKevin Manuspage 20 Ode to My Gin-Soaked OlivesBrianne Bolinpage 21 The Six String PlayerRyan Guimondpage 22 MaxineJay Edwardspage 23 BarefootKrista Bodenpage 24 JulyAdam Funkpage 25 HopeOona Margaret Burkepage 26 UntitledLevy Wooln Dannerpage 27 The One and Only Picture I Have of YouKevin Manuspage 28 Death of a Fat ManBrianne Bolinpage 29-32https://thekeep.eiu.edu/vehicle/1075/thumbnail.jp

    Modular Synthesis of Semiconducting Graft Co-polymers to Achieve "clickable" Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting

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    Semiconducting polymer nanoparticles (SPNs) have been explored for applications in cancer theranostics because of their high absorption coefficients, photostability and biocompatibility. However, SPNs are susceptible to aggregation and protein fouling in physiological conditions, which can be detrimental for in vivo applications. Here, we describe a method for achieving colloidally stable and low-fouling SPNs by grafting PEG onto the backbone of the fluorescent semiconducting polymer, poly(9,9'-dioctylfluorene-5-fluoro-2,1,3-benzothiadiazole) (F8BT-F), in a simple one-step substitution reaction, post-polymerisation. Further, by utilising azide-functionalised PEG we site-specifically "click" anti-HER2 antibodies, Fab fragments, or affibodies onto the SPN surface, which allows the functionalised SPNs to specifically target HER2-positive cancer cells. In vivo, our PEGylated SPNs were found to have excellent circulation efficiencies in zebrafish embryos for up to seven days post-injection. SPNs functionalised with affibodies were then shown to be able to target HER2 expressing cancer cells in a zebrafish xenograft model. The covalent PEGylated SPN system described herein shows great potential for cancer theranostics. This article is protected by copyright. All rights reserved

    Blood Pressure Self-Monitoring in Pregnancy: Examining Feasibility in a Prospective Cohort Study

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    BACKGROUND: Raised blood pressure (BP) affects approximately 10% of pregnancies worldwide, and a high proportion of affected women develop pre-eclampsia. This study aimed to evaluate the feasibility of self-monitoring of BP in pregnancy in women at higher risk of pre-eclampsia. METHODS: This prospective cohort study of self-monitoring BP in pregnancy was carried out in two hospital trusts in Birmingham and Oxford and thirteen primary care practices in Oxfordshire. Eligible women were those defined by the UK National Institute for Health and Care Excellence (NICE) guidelines as at higher risk of pre-eclampsia. A total of 201 participants were recruited between 12 and 16 weeks of pregnancy and were asked to take two BP readings twice daily three times a week through their pregnancy. Primary outcomes were recruitment, retention and persistence of self-monitoring. Study recruitment and retention were analysed with descriptive statistics. Survival analysis was used to evaluate the persistence of self-monitoring and the performance of self-monitoring in the early detection of gestational hypertension, compared to clinic BP monitoring. Secondary outcomes were the mean clinic and self-monitored BP readings and the performance of self-monitoring in the detection of gestational hypertension and pre-eclampsia compared to clinic BP. RESULTS: Of 201 women recruited, 161 (80%) remained in the study at 36 weeks or to the end of their pregnancy, 162 (81%) provided any home readings suitable for analysis, 148 (74%) continued to self-monitor at 20 weeks and 107 (66%) at 36 weeks. Self-monitored readings were similar in value to contemporaneous matched clinic readings for both systolic and diastolic BP. Of the 23 who developed gestational hypertension or pre-eclampsia and self-monitored, 9 (39%) had a raised home BP prior to a raised clinic BP. CONCLUSIONS: Self-monitoring of BP in pregnancy is feasible and has potential to be useful in the early detection of gestational hypertensive disorders but maintaining self-monitoring throughout pregnancy requires support and probably enhanced training
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