Influence of electron motion in target atom on stopping power for low-energetic Ions

In this paper the stopping power was calculated, representing the electrons of the target atom as an assembly of quantum oscillators. It was considered that the electrons in the atoms have some velocity before interaction with the projectile, which is the main contribution of this paper. The influence of electron velocity on stopping power for different projectiles and targets was investigated. It was found that the velocity of the electron stopping power has the greatest influence at low energies of the projectile

Efficacy of nanocrystalline bone substitute biphasic calcium phosphate/poly-DL-lactide-co-glycolide for periodontal intrabony defects filling

Background/Aim. Different bone substitutes have been used for filling and reparation of intrabony defects. The aim of this study was to compare nanocrystalline material, biphasic calcium phosphate poly-DL-lactidecoglycolide (BCP/PLGA) with deproteinised bovine bone (DPBB) and β-tricalcium phosphate (β-TCP) in the treatment of periodontal intrabony defects. Methods. The study included 24 patients with bilateral, intrabony defects in the region of the upper first and second premolar, and the upper first molar. On one side of the mouth, DPBB (BioOss®) was used to fill defects in upper premolars while β-TCP (RTR®) was used for the upper first molar. BCP/PLGA was applied into periodontal defects of the upper premolars and upper first molar of the opposite side. Results. The comparison of the BCP/PLGA and the β-TCP group, 6 months following filling of defects, showed a statistically significant reduction of periodontal pocket depth (PPD) and the position of the cement-enamel junction (CEJ) in the group with BCP/PLGA, when compared to the β-TCP group. The reduction of PPD and CEJ was similar in the groups treated with BCP/PLGA and DPBB. Conclusion. Significant reductions of PPD and CEJ were registered in the group with BCP/PLGA when compared to the β-TCP group. © 2015, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved

Dekompresija kao delotvorni primarni pristup radikularnoj cisti u maksilarnom sinusu

Introduction. Therapeutic approach to jaw cysts may depend on their dimensions and localization. Enucleation of cystic lesion is not always preferable in the first act, especially if large cysts are in close proximity to important anatomical structures. The aim of this paper was to present the outcome of the treatment protocol comprising preoperative decompression and subsequent enucleation of a large maxillary cyst. Case re-port. A 21-year-old male patient with large asymptomatic radicular cyst in the right maxillary sinus was presented to our clinic. Conebeam computed tomography (CBCT) showed a large cyst, which perforated the right anterior maxillary wall by 1.5 cm, and was in the intimate contact with the orbital floor. Surgical treatment of the cystic lesion comprised: preoperative decompression with biopsy in the first act and enucleation, performed under general anesthesia, 6 months after the observation period. Conclusion. Decompression with subsequent enucleation proved to be effective treatment of large radicular cyst in maxillary sinus with low-morbidity.Uvod. Terapijski pristup cistama vilice može zavisiti od njihovih dimenzija i lokalizacije. Enukleacija cistične lezije često nije pogodna u prvom aktu ako se velika cista nalazi u blizini važnih anatomskih struktura. Cilj ovog rada bio je da se prikaže ishod lečenja velike ciste u maksilarnom sinusu koji je podrazumevao preoperativnu dekompresiju i odloženu enukleaciju. Prikaz bolesnika. Prikazan je bolesnik, star 21 godinu, sa velikom, asimptomatskom, radikularnom cistom u maksilarnom sinusu. Radiografska dijagnostika pomoću cone-beam kompjuterizovane tomografije (CBCT), pokazala je prisustvo velike cistične lezije koja je probila prednji maksilarni zid (1,5 cm) i bila u bliskom kontaktu sa podom orbite. Hirurški tretman cistične lezije uključio je preoperativnu dekompresiju i biopsiju u prvom aktu i enukleaciju u opštoj anesteziji nakon 6 meseci. Zaključak. De-kompresija i odložena enukleacija pokazale su se efikasnim terapijskim pristupom kod lečenje velike radikularne ciste maksilarnog sinusa uz mali morbiditet

Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires

Background: The use of nitinol (NiTi) archwires in orthodontic treatment has increased significantly due to unique mechanical properties. The greatest obstacle for safe orthodontic treatment is chemically or microbiologically induced corrosion, resulting in nickel (Ni) release. The aim of this investigation was to enhance corrosion resistance and introduce antibacterial properties to NiTi archwires by coating them with copper (Cu) doper titanium nitride (TiN-Cu). Methods: NiTi archwires were coated with TiN-Cu using cathodic arc evaporation (CAE) and direct current magnetron sputtering (DC-MS). The morphology of the sample was analyzed via field emission scanning electron microscopy (FESEM) and chemical composition was assessed using energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and Fourier transformed infrared spectroscopy (FTIR). Inductively coupled plasma optical emission spectrometry (ICP-OES) was used to estimate the ion release. The biocompatibility of samples was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) assay. Antibacterial activity was tested against Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. TiN-Cu-nanocoated archwires showed a statistically lower Ni release (p < 0.05). Relative cell viability was the highest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The most remarkable decrease in Streptococcus mitis concentrations was observed in the case of TiN-Cu-coated archwires (p < 0.05). Conclusion: Taking into account biocompatibility and antibacterial tests, TiN-Cu-nanocoated archwires may be considered as a good candidate for further clinical investigation

Comparison of Hydroxyapatite/Poly(lactide-co-glycolide) and Hydroxyapatite/Polyethyleneimine Composite Scaffolds in Bone Regeneration of Swine Mandibular Critical Size Defects: In Vivo Study

Reconstruction of jaw bone defects present a significant problem because of specific aesthetic and functional requirements. Although widely used, the transplantation of standard autograft and allograft materials is still associated with significant constraints. Composite scaffolds, combining advantages of biodegradable polymers with bioceramics, have potential to overcome limitations of standard grafts. Polyethyleneimine could be an interesting novel biocompatible polymer for scaffold construction due to its biocompatibility and chemical structure. To date, there have been no in vivo studies assessing biological properties of hydroxyapatite bioceramics scaffold modified with polyethyleneimine. The aim of this study was to evaluate in vivo effects of composite scaffolds of hydroxyapatite ceramics and poly(lactide-co-glycolide) and novel polyethyleneimine on bone repair in swine’s mandibular defects, and to compare them to conventional bone allograft (BioOss). Scaffolds were prepared using the method of polymer foam template in three steps. Pigs, 3 months old, were used and defects were made in the canine, premolar, and molar area of their mandibles. Four months following the surgical procedure, the bone was analyzed using radiological, histological, and gene expression techniques. Hydroxyapatite ceramics/polyethyleneimine composite scaffold demonstrated improved biological behavior compared to conventional allograft in treatment of swine’s mandibular defects, in terms of bone density and bone tissue histological characteristics

Evaluaton of the Use of Bone Implants as a Therapy for Deep Defects in the Parodoncium

Osnovni klinički problem u terapiji parodontopatije predstavlja rekonstrukcija infrakoštanih defekata nastalih u toku hroničnog inflamatornog procesa

The efficacy of using 'biohapel' in the therapy of infrabony periodontal defects

Vertical type of the alveolar bone resorption causes formation of periodontal pockets of infrabony type. Presence of these kinds of defects, from the aspect of a plan of therapy and the therapy itself represents a serious problem. The aim of this research was to test the efficacy of tissue regeneration of periodontal infrabony defects after using a new material 'Biohapel'. This study included 16 patients, males and females, of the average age of 48.6, all of them suffering from clinically manifested periodontal disease. The inclusion criteria for the study was presence of at least two similar periodontal defects 5 mm deep at least, around the same mandibular posterior teeth, bilaterally. After conducting initial therapy, the defects were divided into 2 groups - experimental group (n=16) which was reconstructed with 'Biohapel' implant (one side of the mandible) and control group (n=16), where standard surgical procedure was applied (other side of the mandible). The assessment of periodontal tissues conditions was verified, before and 6 months after the surgical procedure was performed, measuring periodontal pocket depth and the clinical attachment level. Statistically significant difference between experimental and control group was noticed (p<0.05), in regar to the tested parameters of periodontal regeneration. Use of' Biohapel' in therapy of infrabony periodontal defects indicates highly significant level of bone regeneration in comparison with the standard surgical procedure

Efficacy of nanocrystalline bone substitute biphasic calcium phosphate/poly-DL-lactide-co-glycolide for periodontal intrabony defects filling

Background/Aim. Different bone substitutes have been used for filling and reparation of intrabony defects. The aim of this study was to compare nanocrystalline material, biphasic calcium phosphate poly-DL-lactide-co-glycolide (BCP/PLGA) with deproteinised bovine bone (DPBB) and β-tricalcium phosphate (β- TCP) in the treatment of periodontal intrabony defects. Methods. The study included 24 patients with bilateral, intrabony defects in the region of the upper first and second premolar, and the upper first molar. On one side of the mouth, DPBB (BioOss®) was used to fill defects in upper premolars while β- TCP (RTR®) was used for the upper first molar. BCP/PLGA was applied into periodontal defects of the upper premolars and upper first molar of the opposite side. Results. The comparison of the BCP/PLGA and the β-TCP group, 6 months following filling of defects, showed a statistically significant reduction of periodontal pocket depth (PPD) and the position of the cementenamel junction (CEJ) in the group with BCP/PLGA, when compared to the β-TCP group. The reduction of PPD and CEJ was similar in the groups treated with BCP/PLGA and DPBB. Conclusion. Significant reductions of PPD and CEJ were registered in the group with BCP/PLGA when compared to the β- TCP group. [Projekat Ministarstva nauke Republike Srbije, br. 175021 i br. III45004

Efficacy of nanocrystalline bone substitute biphasic calcium phosphate/poly-DL-lactide-co-glycolide for periodontal intrabony defects filling

Background/Aim. Different bone substitutes have been used for filling and reparation of intrabony defects. The aim of this study was to compare nanocrystalline material, biphasic calcium phosphate poly-DL-lactide-co-glycolide (BCP/PLGA) with deproteinised bovine bone (DPBB) and β-tricalcium phosphate (β- TCP) in the treatment of periodontal intrabony defects. Methods. The study included 24 patients with bilateral, intrabony defects in the region of the upper first and second premolar, and the upper first molar. On one side of the mouth, DPBB (BioOss®) was used to fill defects in upper premolars while β- TCP (RTR®) was used for the upper first molar. BCP/PLGA was applied into periodontal defects of the upper premolars and upper first molar of the opposite side. Results. The comparison of the BCP/PLGA and the β-TCP group, 6 months following filling of defects, showed a statistically significant reduction of periodontal pocket depth (PPD) and the position of the cementenamel junction (CEJ) in the group with BCP/PLGA, when compared to the β-TCP group. The reduction of PPD and CEJ was similar in the groups treated with BCP/PLGA and DPBB. Conclusion. Significant reductions of PPD and CEJ were registered in the group with BCP/PLGA when compared to the β- TCP group. [Projekat Ministarstva nauke Republike Srbije, br. 175021 i br. III45004

Influence of electron motion in target atom on stopping power for low-energetic ions

In this paper the stopping power was calculated, representing the electrons of the target atom as an assembly of quantum oscillators. It was considered that the electrons in the atoms have some velocity before interaction with the projectile, which is the main contribution of this paper. The influence of electron velocity on stopping power for different projectiles and targets was investigated. It was found that the velocity of the electron stopping power has the greatest influence at low energies of the projectile