72 research outputs found

    Leaving Siegfried Behind: Nibelung Monuments In The Cultural Infrastructure Of Contemporary Austria - YouTube Video Link (https://www.youtube.com/watch?v=DZ5YVKGfDYk&feature=youtu.be)

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    This is part of a larger project called Medieval Literature in the Modern Landscape: Culture and Heritage in Contemporary Austria. It was begun at the Karl Franzens University of Graz, where I was the Fulbright Visiting Professor of Cultural Studies in the spring/summer 2020. YouTube link: https://www.youtube.com/watch?v=DZ5YVKGfDYk&feature=youtu.be

    Leaving Siegfried Behind: Nibelung Monuments In The Cultural Infrastructure Of Contemporary Austria

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    This is part of a larger project called Medieval Literature in the Modern Landscape: Culture and Heritage in Contemporary Austria. It was begun at the Karl Franzens University of Graz, where I was the Fulbright Visiting Professor of Cultural Studies in the spring/summer 2020

    Medieval Literature On Display

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    Medieval Literature on Display is a monograph (currently in press with Bloomsbury, publication date of January 2020) on the role of medievalism in practice of cultural memory and the creation of heritage. The book focuses on two case studies from the time immediately following the reunification of Germany in 1990. Both case studies involve German museums dedicated to medieval literature: the first is the Museum Wolfram von Eschenbach in Wolframs-Eschenbach (1995); the second is the Nibelung Museum in Worms (2001). Largely unknown to wider audiences outside of their geographic regions, these museums deserve greater attention. They reveal how memory, through the lens of the Middle Ages, shapes modern cultural identity and heritage

    Warnings & fables

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    These poems explore the nature of restlessness through a variety of landscapes and personas, both historical and imaginary. Many of these poems draw on elements of the traditional fable by investigating the risks of leave-taking, the journey, and the danger of curiosit

    The Role Of Race On The Prevalence Of And Perceived Response To Workplace Sexual Harassment

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    Research has shown that minority women experience compounding forms of discrimination as identities intersect, namely sex and race. Though sexual harassment (SH) has been examined, notably in the workplace, the literature routinely fails to capture the full experience of minority women. Further, the intersection between race of the victim and race of the perpetrator appears understudied despite the function of SH being to maintain systems of power and reinforce patterns of discrimination. It was hypothesized that minority women will experience greater rates of SH, specifically perpetrated by White men. Additionally, it was hypothesized that minority women will be less likely to report SH, and if they report, they will be more likely to perceive that their complaint(s) is (are) not taken seriously compared to White female counterparts. The Sexual Experiences Questionnaire (SEQ) was administered to respondents along with a measure of reporting and of perceived seriousness of complaint handling. There was no support that for any of the hypotheses. The direction of the relationship between victim race and perpetrator race in relation to workplace SH reveals that intraracial workplace SH may occur more frequently than interracial workplace SH. Future research should explore the incidence of intraracial workplace SH

    Matrix Rigidity Induces Osteolytic Gene Expression of Metastatic Breast Cancer Cells

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    Nearly 70% of breast cancer patients with advanced disease will develop bone metastases. Once established in bone, tumor cells produce factors that cause changes in normal bone remodeling, such as parathyroid hormone-related protein (PTHrP). While enhanced expression of PTHrP is known to stimulate osteoclasts to resorb bone, the environmental factors driving tumor cells to express PTHrP in the early stages of development of metastatic bone disease are unknown. In this study, we have shown that tumor cells known to metastasize to bone respond to 2D substrates with rigidities comparable to that of the bone microenvironment by increasing expression and production of PTHrP. The cellular response is regulated by Rho-dependent actomyosin contractility mediated by TGF-ß signaling. Inhibition of Rho-associated kinase (ROCK) using both pharmacological and genetic approaches decreased PTHrP expression. Furthermore, cells expressing a dominant negative form of the TGF-ß receptor did not respond to substrate rigidity, and inhibition of ROCK decreased PTHrP expression induced by exogenous TGF-ß. These observations suggest a role for the differential rigidity of the mineralized bone microenvironment in early stages of tumor-induced osteolysis, which is especially important in metastatic cancer since many cancers (such as those of the breast and lung) preferentially metastasize to bone

    Physical conditions and chemical abundances in photoionized nebulae from optical spectra

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    This chapter presents a review on the latest advances in the computation of physical conditions and chemical abundances of elements present in photoionized gas H II regions and planetary nebulae). The arrival of highly sensitive spectrographs attached to large telescopes and the development of more sophisticated and detailed atomic data calculations and ionization correction factors have helped to raise the number of ionic species studied in photoionized nebulae in the last years, as well as to reduce the uncertainties in the computed abundances. Special attention will be given to the detection of very faint lines such as heavy-element recombination lines of C, N and O in H II regions and planetary nebulae, and collisionally excited lines of neutron-capture elements (Z >30) in planetary nebulae.Comment: Book Chapter. 31 pages. 6 Figures. Accepted for publication in the book "Reviews in Frontiers of Modern Astrophysics: From Space Debris to Cosmology" (eds Kabath, Jones and Skarka; publisher Springer Nature) funded by the European Union Erasmus+ Strategic Partnership grant "Per Aspera Ad Astra Simul" 2017-1-CZ01-KA203-03556

    A comparison of four fibrosis indexes in chronic HCV: Development of new fibrosis-cirrhosis index (FCI)

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    <p>Abstract</p> <p>Background</p> <p>Hepatitis C can lead to liver fibrosis and cirrhosis. We compared readily available non-invasive fibrosis indexes for the fibrosis progression discrimination to find a better combination of existing non-invasive markers.</p> <p>Methods</p> <p>We studied 157 HCV infected patients who underwent liver biopsy. In order to differentiate HCV fibrosis progression, readily available AAR, APRI, FI and FIB-4 serum indexes were tested in the patients. We derived a new fibrosis-cirrhosis index (FCI) comprised of ALP, bilirubin, serum albumin and platelet count. FCI = [(ALP × Bilirubin) / (Albumin × Platelet count)].</p> <p>Results</p> <p>Already established serum indexes AAR, APRI, FI and FIB-4 were able to stage liver fibrosis with correlation coefficient indexes 0.130, 0.444, 0.578 and 0.494, respectively. Our new fibrosis cirrhosis index FCI significantly correlated with the histological fibrosis stages F0-F1, F2-F3 and F4 (r = 0.818, p < 0.05) with AUROCs 0.932 and 0.996, respectively. The sensitivity and PPV of FCI at a cutoff value < 0.130 for predicting fibrosis stage F0-F1 was 81% and 82%, respectively with AUROC 0.932. Corresponding value of FCI at a cutoff value ≥1.25 for the prediction of cirrhosis was 86% and 100%.</p> <p>Conclusions</p> <p>The fibrosis-cirrhosis index (FCI) accurately predicted fibrosis stages in HCV infected patients and seems more efficient than frequently used serum indexes.</p
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