Of Federalism, Human Rights, and the \u3cem\u3eHolland\u3c/em\u3e Caveat: Congressional Power to Iplement Treaties

This Article explores whether the Rehnquist Court\u27s federalism doctrine, as elaborated during this last decade, should or ought to extend to the domestication of discrete provisions of ratified human rights treaties. It explores this question by examining the International Covenant on Civil and Political Rights (Covenant) and by considering the civil remedy provision of Violence Against Women Act (VAWA) as potential implementing legislation for the equality provisions of the Covenant. In the context of this inquiry, the discussion engages federalism, as developed by the current Court, on its own terms. That is, I do not seek here to defend it or reject it. It seeks to refocus the broader debate to the specific context of the VAWA and the ICCPR

Of Federalism, Human Rights, and the \u3cem\u3eHolland\u3c/em\u3e Caveat: Congressional Power to Iplement Treaties

This Article explores whether the Rehnquist Court\u27s federalism doctrine, as elaborated during this last decade, should or ought to extend to the domestication of discrete provisions of ratified human rights treaties. It explores this question by examining the International Covenant on Civil and Political Rights (Covenant) and by considering the civil remedy provision of Violence Against Women Act (VAWA) as potential implementing legislation for the equality provisions of the Covenant. In the context of this inquiry, the discussion engages federalism, as developed by the current Court, on its own terms. That is, I do not seek here to defend it or reject it. It seeks to refocus the broader debate to the specific context of the VAWA and the ICCPR

Incorporating the nursing and midwifery Aboriginal and Torres Strait Islander health curriculum framework into a BN program

When considering Aboriginal and Torres Strait Islander people\u27s culture, the appropriate approach with students should be to explore and reflect upon cultural safety initially followed by context, with an overlay of Aboriginal and Torres Strait Islander health throughout. * Learning outcomes should be reflective of this process throughout a curriculum - novice, intermediate and entry to practice, developing complexity throughout a degree to increase understanding and application. * Using the CATSINaM Nursing and Midwifery Aboriginal and Torres Strait Islander Health Curriculum Framework will facilitate progression and integration into curriculum. * How can I develop Aboriginal and non-Aboriginal partnerships to cocreate curriculum content

Specific Functions of BIG1 and BIG2 in Endomembrane Organization

Background: Transport of molecules from one subcellular compartment to another involves the recruitment of cytosolic coat protein complexes to a donor membrane to concentrate cargo, deform the membrane and ultimately to form an independent carrier. Small-GTP-binding proteins of the Arf family are central to many membrane trafficking events. Arfs are activated by guanine nucleotide exchange factors (GEFs) which results in their recruitment to membranes and subsequent engagement with Arf-effectors, many of which are coat proteins. Among the human BFA-sensitive large Arf-GEFs, the function of the two closely related BIG1 and BIG2 is still not clear, and recent studies have raised the question of functional redundancy between the two proteins. Methodology/Principal Findings: Here we have used small-interfering RNA on human cells and a combination of fixed and live-cell imaging to investigate the differential functions of BIG1 and BIG2 in endomembrane organization and function. Importantly, in this direct comparative study, we show discrete functions for BIG1 and BIG2. Our results show that depletion of BIG2 but not of BIG1 induces a tubulation of the recycling endosomal compartment, consistent with a specific role for BIG2 here. In contrast, suppression of BIG1 induces the formation of Golgi mini-stacks still polarized and functional in terms of cargo export. Conclusions: A key finding from our work is that suppression of BIG1 expression results in a fragmentation of the Golg

Initiatives to Find the Lost Einsteins through the Integration of Independent Scientific Research Projects in Early College

This exploratory study examines the effects of incorporating Independent Scientific Research Projects (ISRP) into early college biology curriculum. The authors present their findings, which are steeped in the goal of increasing minority students’ interest in STEM careers, by analyzing student engagement in classrooms with and without ISRP integration

Draft Genome Sequence of a Community-Associated Methicillin- Resistant Panton-Valentine Leukocidin-Positive Staphylococcus aureus Sequence Type 30 Isolate from a Pediatric Patient with a Lung Infection in Brazil

The sequence of methicillin-resistant Staphylococcus aureus strain B6 (sequence type 30 [ST30], spa type t433, staphylococcal chromosomal cassette mec element [SCCmec] type IVc, Panton-Valentine leukocidin [PVL] positive), isolated from a pediatric patient with a lung infection in Niterói, Rio de Janeiro, Brazil, is described here. The draft genome sequence includes a 2.8-Mb chromosome, accompanied by a 20-kb plasmid containing blaZ and two small cryptic plasmids

Supporting English Literacy and Numeracy Learning for Indigenous Students in the Early Years

A longitudinal study conducted by ACER has been monitoring the growth in English literacy and numeracy achievement of a group of 152 Indigenous students in 13 schools through the early years of primary school. Indigenous students\u27 developing English literacy and numeracy skills were assessed at five points over the first three years of school using tasks developed for the ACER Longitudinal Literacy and Numeracy Survey (LLANS). In general, for both the English literacy and for numeracy the achievement of the Indigenous students began at a similar level to that of the main LLANS sample but by the time of the fifth assessment in the third year of school substantial gaps had emerged