55 research outputs found
Controlling the superconducting transition by spin-orbit coupling
Whereas there exists considerable evidence for the conversion of singlet
Cooper pairs into triplet Cooper pairs in the presence of inhomogeneous
magnetic fields, recent theoretical proposals have suggested an alternative way
to exert control over triplet generation: intrinsic spin-orbit coupling in a
homogeneous ferromagnet coupled to a superconductor. Here, we proximity-couple
Nb to an asymmetric Pt/Co/Pt trilayer, which acts as an effective spin-orbit
coupled ferromagnet owing to structural inversion asymmetry. Unconventional
modulation of the superconducting critical temperature as a function of
in-plane and out-of- plane applied magnetic fields suggests the presence of
triplets that can be controlled by the magnetic orientation of a single
homogeneous ferromagnet. Our studies demonstrate for the first time an active
role of spin-orbit coupling in controlling the triplets -- an important step
towards the realization of novel superconducting spintronic devices.Comment: 11 pages + 4 figures + supplemental informatio
A new kind of vortex pinning in superconductor / ferromagnet nanocomposites
This paper reports the observation of hysteresis in the vortex pinning in a
superconductor / ferromagnetic epitaxial nanocomposite consisting of fcc Gd
particles incorporated in a Nb matrix. We show that this hysteretic pinning is
associated with magnetic reversal losses in the Gd particles and is
fundamentally different in origin to pinning interactions previously observed
for ferromagnetic particles or other microstructural features.Comment: Submitted to PR
Disorder induced collapse of the electron phonon coupling in MgB observed by Raman Spectroscopy
The Raman spectrum of the superconductor MgB has been measured as a
function of the Tc of the film. A striking correlation is observed between the
onset and the frequency of the mode. Analysis of the data with
the McMillan formula provides clear experimental evidence for the collapse of
the electron phonon coupling at the temperature predicted for the convergence
of two superconducting gaps into one observable gap. This gives indirect
evidence of the convergence of the two gaps and direct evidence of a transition
to an isotropic state at 19 K. The value of the electron phonon coupling
constant is found to be 1.22 for films with T 39K and 0.80 for films with
T19K.Comment: 5 pages, 4 figure
Fast Gate-Based Readout of Silicon Quantum Dots Using Josephson Parametric Amplification
Spins in silicon quantum devices are promising candidates for large-scale quantum computing. Gate-based sensing of spin qubits offers a compact and scalable readout with high fidelity, however, further improvements in sensitivity are required to meet the fidelity thresholds and measurement timescales needed for the implementation of fast feedback in error correction protocols. Here, we combine radio-frequency gate-based sensing at 622 MHz with a Josephson parametric amplifier, that operates in the 500–800 MHz band, to reduce the integration time required to read the state of a silicon double quantum dot formed in a nanowire transistor. Based on our achieved signal-to-noise ratio, we estimate that singlet-triplet single-shot readout with an average fidelity of 99.7% could be performed in
1
μ
s
, well below the requirements for fault-tolerant readout and 30 times faster than without the Josephson parametric amplifier. Additionally, the Josephson parametric amplifier allows operation at a lower radio-frequency power while maintaining identical signal-to-noise ratio. We determine a noise temperature of 200 mK with a contribution from the Josephson parametric amplifier (25%), cryogenic amplifier (25%) and the resonator (50%), showing routes to further increase the readout speed
Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis
Excessive accumulation of lipid inclusions in the arterial wall cells (foam cell formation) caused by modified low-density lipoprotein (LDL) is the earliest and most noticeable manifestation of atherosclerosis. The mechanisms of foam cell formation are not fully understood and can involve altered lipid uptake, impaired lipid metabolism, or both. Recently, we have identified the top 10 master regulators that were involved in the accumulation of cholesterol in cultured macrophages induced by the incubation with modified LDL. It was found that most of the identified master regulators were related to the regulation of the inflammatory immune response, but not to lipid metabolism. A possible explanation for this unexpected result is a stimulation of the phagocytic activity of macrophages by modified LDL particle associates that have a relatively large size. In the current study, we investigated gene regulation in macrophages using transcriptome analysis to test the hypothesis that the primary event occurring upon the interaction of modified LDL and macrophages is the stimulation of phagocytosis, which subsequently triggers the pro-inflammatory immune response. We identified genes that were up- or downregulated following the exposure of cultured cells to modified LDL or latex beads (inert phagocytosis stimulators). Most of the identified master regulators were involved in the innate immune response, and some of them were encoding major pro-inflammatory proteins. The obtained results indicated that pro-inflammatory response to phagocytosis stimulation precedes the accumulation of intracellular lipids and possibly contributes to the formation of foam cells. In this way, the currently recognized hypothesis that the accumulation of lipids triggers the pro-inflammatory response was not confirmed. Comparative analysis of master regulators revealed similarities in the genetic regulation of the interaction of macrophages with naturally occurring LDL and desialylated LDL. Oxidized and desialylated LDL affected a different spectrum of genes than naturally occurring LDL. These observations suggest that desialylation is the most important modification of LDL occurring in vivo. Thus, modified LDL caused the gene regulation characteristic of the stimulation of phagocytosis. Additionally, the knock-down effect of five master regulators, such as IL15, EIF2AK3, F2RL1, TSPYL2, and ANXA1, on intracellular lipid accumulation was tested. We knocked down these genes in primary macrophages derived from human monocytes. The addition of atherogenic naturally occurring LDL caused a significant accumulation of cholesterol in the control cells. The knock-down of the EIF2AK3 and IL15 genes completely prevented cholesterol accumulation in cultured macrophages. The knock-down of the ANXA1 gene caused a further decrease in cholesterol content in cultured macrophages. At the same time, knock-down of F2RL1 and TSPYL2 did not cause an effect. The results obtained allowed us to explain in which way the inflammatory response and the accumulation of cholesterol are related confirming our hypothesis of atherogenesis development based on the following viewpoints: LDL particles undergo atherogenic modifications that, in turn, accompanied by the formation of self-associates; large LDL associates stimulate phagocytosis; as a result of phagocytosis stimulation, pro-inflammatory molecules are secreted; these molecules cause or at least contribute to the accumulation of intracellular cholesterol. Therefore, it became obvious that the primary event in this sequence is not the accumulation of cholesterol but an inflammatory response
Microstructural studies of plastic indentations at low loads
SIGLEAvailable from British Library Document Supply Centre-DSC:D198856 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
LOCAL DEVELOPMENT OF ALTERNATIVE ENERGY IN THE CONDITIONS OF GLOBALIZATION AS A FACTOR OF REDUCING RISKS AND MODERNIZING THE ECONOMY OF THE COUNTRY
The main direction of modernization of the world energy is the development of the so-called alternative (unconventional) energy, which implies the use of sources,
technologies and forms of organizing energy production other than those currently dominant in a given country (region). The diversification of the economy, achieved
through the development of alternative energy and other components of "green" growth, makes it possible to mitigate the crisis situation, the problem of employment
in particular, and at the same time enhances the competitiveness of energy producers by obtaining new promising niches in the world market. When assessing the
significance and prospects of alternative energy, we should not talk about replacing conventional sources, but about supplementing, diversifying the existing base of
energy production at the local (regional) level with less capital-intensive installations on local renewable energy sources
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