Multiple Slips in Atomic-Scale Friction: An Indicator for the Lateral Contact Damping

The occurrence of multiple jumps in 2D atomic-scale friction measurements is used to quantify the viscous damping accompanying the stick-slip motion of a sharp tip in contact with a NaCl(001) surface. Multiple slips are observed without apparent wear for normal forces between 13 and 91nN. For scans parallel to [100] directions, the tip jumps between minima of the substrate corrugation potential in a zigzag fashion. An algorithm is applied to determine histograms of lateral force jumps which characterize multiple slips. The same algorithm is used to classify multiple slips occurring in calculated lateral force maps. Comparisons between simulations and experiments indicate that the nanometer-sized contact is underdamped at intermediate loads (13-26nN) and becomes slightly overdamped at higher loads. The proposed procedure is a novel way to estimate the lateral contact damping which plays an important role in the interpretation of measurements of the velocity and temperature dependence of friction, of slip duration, and of the reduction of friction by applied perpendicular or parallel oscillation

Atomic Friction Investigations on Ordered Superstructures

We review recent friction measurements on ordered superstructures performed by atomic force microscopy. In particular, we consider ultrathin KBr films on NaCl(001) and Cu(001) surfaces, single and bilayer graphene on SiC(0001), and the herringbone reconstruction of Au(111). Atomically resolved friction images of these systems show periodic features spanning across several unit cells. Although the physical mechanisms responsible for the formation of these superstructures are quite different, the experimental results can be interpreted within the same phenomenological framework. A comparison between experiments and modeling shows that, in the cases of KBr films on NaCl(001) and of graphene films, the tip-surface interaction is well described by a potential with the periodicity of the substrate which is modulated or, respectively, superimposed with a potential with the symmetry of the superstructur

Correlation of intestinal histopathologic findings with mucosa-attached bacteria, clinical disease activity, and clinical outcome in dogs with chronic enteropathies

Peer reviewe

Feldleistungsprüfung Schaf

In Schafzuchtbetrieben wurden die Einflussfaktoren auf das Wachstum von Schaflämmern verschiedener Rassen für Feldleistungsprüfungen bewertet. Im Ergebnis konnten der optimale Zeitpunkt der Erfassung der Wachstumsdaten, Art und Umfang der Leistungsermittlung und deren Einordnung in das Prüfsystem des Zuchtprogramms abgeleitet werden. In acht Zuchtbetrieben wurden von 4.000 Lämmern verschiedener Rassen Geburtsgewichte sowie 60-Tage- und 100-Tage-Gewichte erhoben. Das Geburtsgewicht beeinflusst im entscheidenden Maße das Wachstum bis zum 100. Lebenstag. Es wird am stärksten vom Geburtstyp beeinflusst, dann erst von Rasse und Geschlecht. Bei den erfassten Lämmern sind über alle Rassen die Lebendmassezunahmen mit 304 g/Tier und Tag bis zum 60. Lebenstag bzw. 302 g/Tier und Tag bis zum 100. Lebenstag (bei Berücksichtigung des Geburtsgewichtes) nahezu gleich. Mit den Untersuchungsergebnissen können die bisher verwendeten standardisierten Geburtsgewichte aktualisiert werden. Es wird empfohlen, dass bei der Festlegung von Standard-Geburtsgewichten die Faktoren Rasse, Geburtstyp und Geschlecht Berücksichtigung finden sollten. Die Ergebnisse liefern allen mit der Schafzucht befassten Personen, Unternehmen und Verbänden wichtige Erkenntnisse für die künftige Gestaltung des Prüfsystems

Clumpy wind studies and the non-detection of cyclotron line in OAO 1657-415

Winds of massive stars are suspected to be inhomogeneous (or clumpy), which biases the measures of their mass loss rates. In High Mass X-ray Binaries (HMXBs), the compact object can be used as an orbiting X-ray point source to probe the wind and constrain its clumpiness. We perform spectro-timing analysis of the HMXB OAO 1657-415 with non-simultaneous NuSTAR and NICER observations. We compute the hardness ratio from the energy-resolved light curves, and using an adaptive rebinning technique, we thus select appropriate time segments to search for rapid spectral variations on timescales of a few hundreds to thousands of seconds. Column density and intensity of Iron K$\alpha$ line were strongly correlated, and the recorded spectral variations were consistent with accretion from a clumpy wind. We also illustrate a novel framework to measure clump sizes, masses in HMXBs more accurately based on absorption measurements and orbital parameters of the source. We then discuss the limitations posed by current X-ray spacecrafts in such measurements and present prospects with future X-ray missions. We find that the source pulse profiles show a moderate dependence on energy. We identify a previously undetected dip in the pulse profile visible throughout the NuSTAR observation near spin phase 0.15 possibly caused by intrinsic changes in accretion geometry close to the neutron star. We do not find any evidence for the debated cyclotron line at $\sim$ 36\,keV in the time-averaged or the phase-resolved spectra with NuSTAR.Comment: 32 pages, 11 figures in main text, 7 figures in Appendix, Accepted for publication in Ap

Catching Element Formation In The Act

Gamma-ray astronomy explores the most energetic photons in nature to address some of the most pressing puzzles in contemporary astrophysics. It encompasses a wide range of objects and phenomena: stars, supernovae, novae, neutron stars, stellar-mass black holes, nucleosynthesis, the interstellar medium, cosmic rays and relativistic-particle acceleration, and the evolution of galaxies. MeV gamma-rays provide a unique probe of nuclear processes in astronomy, directly measuring radioactive decay, nuclear de-excitation, and positron annihilation. The substantial information carried by gamma-ray photons allows us to see deeper into these objects, the bulk of the power is often emitted at gamma-ray energies, and radioactivity provides a natural physical clock that adds unique information. New science will be driven by time-domain population studies at gamma-ray energies. This science is enabled by next-generation gamma-ray instruments with one to two orders of magnitude better sensitivity, larger sky coverage, and faster cadence than all previous gamma-ray instruments. This transformative capability permits: (a) the accurate identification of the gamma-ray emitting objects and correlations with observations taken at other wavelengths and with other messengers; (b) construction of new gamma-ray maps of the Milky Way and other nearby galaxies where extended regions are distinguished from point sources; and (c) considerable serendipitous science of scarce events -- nearby neutron star mergers, for example. Advances in technology push the performance of new gamma-ray instruments to address a wide set of astrophysical questions.Comment: 14 pages including 3 figure

Long Range Plan: Dense matter theory for heavy-ion collisions and neutron stars

Since the release of the 2015 Long Range Plan in Nuclear Physics, major events have occurred that reshaped our understanding of quantum chromodynamics (QCD) and nuclear matter at large densities, in and out of equilibrium. The US nuclear community has an opportunity to capitalize on advances in astrophysical observations and nuclear experiments and engage in an interdisciplinary effort in the theory of dense baryonic matter that connects low- and high-energy nuclear physics, astrophysics, gravitational waves physics, and data scienceComment: 70 pages, 3 figures, White Paper for the Long Range Plan for Nuclear Scienc

A calculator program for clinical application of the Bayesian method of predicting plasma drug levels

A pharmacokinetic program that allows individualization of drug dosage regimens through the Bayesian method is described. The program, which is designed for the Hewlett-Packard HP-41 CV calculator, is based upon the one-compartment open model with either instantaneous or zero-order absorption. Individualized estimation of the patient's kinetic parameters (clearance and volume of distribution) is performed by analyzing the plasma levels measured in the patient as well as considering the population data of the drug. After estimating the individual kinetic parameters by the Bayesian method, the program predicts the dosage regimen that will elicit the desired peak and trough plasma levels at steady state. For comparison purposes, the least-squares estimates for clearance and volume of distribution are calculated, and dosage prediction can also be made on the basis of the least-squares estimates. The least-squares estimates can be used to calculate population pharmacokinetic parameters according to the Standard Two-Stage method.Several examples of clinical use of the program are presented. The examples refer to patients with classic hemophilia who were treated with Factor VIII concentrates. In these patients, the Bayesian kinetic parameters of Factor VIII have been estimated through the calculator program. The Bayesian parameter estimates generated by the HP-41 have been compared with those determined by a Bayesian program (ADVISE) designed for microcomputers.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/25858/1/0000421.pd