77 research outputs found
Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Border disease
Non peer reviewe
Contribution of cats and dogs to SARS-CoV-2 transmission in households
INTRODUCTION: SARS-CoV-2 is known to jump across species. The occurrence of transmission in households between humans and companion animals has been shown, but the contribution of companion animals to the overall transmission within a household is unknown. The basic reproduction number ( R 0) is an important indicator to quantify transmission. For a pathogen with multiple host species, such as SARS-CoV-2, the basic reproduction number needs to be calculated from the partial reproduction numbers for each combination of host species. METHOD: In this study, the basic and partial reproduction numbers for SARS-CoV-2 were estimated by reanalyzing a survey of Dutch households with dogs and cats and minimally one SARS-CoV-2-infected human. RESULTS: For households with cats, a clear correlation between the number of cats and the basic reproduction number (Spearman's correlation: p 0.40, p-value: 1.4 × 10 -5) was identified, while for dogs, the correlation was smaller and not significant (Spearman's correlation: p 0.12, p-value: 0.21). Partial reproduction numbers from cats or dogs to humans were 0.3 (0.0-2.0) and 0.3 (0.0-3.5) and from humans to cats or dogs were 0.6 (0.4-0.8) and 0.6 (0.4-0.9). DISCUSSION: Thus, the estimations of within-household transmission indicated the likelihood of transmission from these companion animals to humans and vice versa, but the observational nature of this study limited the ability to establish conclusive evidence. This study's findings support the advice provided during the pandemic to COVID-19 patients to maintain distance from companion animals as a precautionary measure and given the possibility of transmission, although there is an overall relatively limited impact on the pandemic when compared to human-to-human transmission
Scientific Opinion on peste des petits ruminants
Peste des petits ruminants (PPR) is a severe viral disease of small ruminants caused by a Morbillivirus closely related to rinderpest virus. It is widespread in Africa and Asia and is currently also found in Turkey and Northern Africa. PPR is transmitted via direct contact, and the disease would mainly be transferred to infection-free areas by transport of infected animals. In the EU, it could only happen through illegal transport of animals. The risk of that depends on the prevalence in the country of origin and the number of animals illegally moved. The extent of the spread would depend mainly on the time during which it is undetected, the farm density, the frequency and distance of travel of animals. PPR has a high within-herd transmission rate, therefore contacts between flocks, e.g. through common grazing areas, should be avoided when PPR is present. If PPR enters EU areas with dense sheep population but low goat density, it may spread rapidly undetected, since goats are considered more susceptible than sheep. Effective measures in limiting the spread of PPR in the EU include prompt culling of infected herds, rapid detection, movement restriction, and disinfection. Live attenuated vaccines against PPR are available, safe and effective, and have been successfully used to control PPR epidemics, but no method exists for differentiating between infected and vaccinated animals; therefore, the development of one is recommended. Awareness-raising campaigns for farmers and veterinary staff to promote recognition of the disease should be considered. The cooperation of the EU with neighbouring countries should be encouraged to prevent the spread 20 of PPR and other transboundary diseases
Phylodynamics of Highly Pathogenic Avian Influenza A(H5N1) Virus Circulating in Indonesian Poultry
After its first detection in 1996, the highly pathogenic avian influenza A(H5Nx) virus has spread extensively worldwide. HPAIv A(H5N1) was first detected in Indonesia in 2003 and has been endemic in poultry in this country ever since. However, Indonesia has limited information related to the phylodynamics of HPAIv A(H5N1) in poultry. The present study aimed to increase the understanding of the evolution and temporal dynamics of HPAIv H5N1 in Indonesian poultry between 2003 and 2016. To this end, HPAIv A(H5N1) hemagglutinin sequences of viruses collected from 2003 to 2016 were analyzed using Bayesian evolutionary analysis sampling trees. Results indicated that the common ancestor of Indonesian poultry HPAIv H5N1 arose approximately five years after the common ancestor worldwide of HPAI A(H5Nx). In addition, this study indicated that only two introductions of HPAIv A(H5N1) occurred, after which these viruses continued to evolve due to extensive spread among poultry. Furthermore, this study revealed the divergence of H5N1 clade 2.3.2.1c from H5N1 clade 2.3.2.1b. Both clades 2.3.2.1c and 2.3.2.1b share a common ancestor, clade 1, suggesting that clade 2.3.2.1 originated and diverged from China and other Asian countries. Since there was limited sequence and surveillance data for the HPAIv A(H5N1) from wild birds in Indonesia, the exact role of wild birds in the spread of HPAIv in Indonesia is currently unknown. The evolutionary dynamics of the Indonesian HPAIv A(H5N1) highlight the importance of continuing and improved genomic surveillance and adequate control measures in the different regions of both the poultry and wild birds. Spatial genomic surveillance is useful to take adequate control measures. Therefore, it will help to prevent the future evolution of HPAI A(H5N1) and pandemic threats
Assessing the health status of managed honeybee colonies (HEALTHY-B): a toolbox to facilitate harmonised data collection
Tools are provided to assess the health status of managed honeybee colonies by facilitating further
harmonisation of data collection and reporting, design of field surveys across the European Union (EU)
and analysis of data on bee health. The toolbox is based on characteristics of a healthy managed
honeybee colony: an adequate size, demographic structure and behaviour; an adequate production of
bee products (both in relation to the annual life cycle of the colony and the geographical location); and
provision of pollination services. The attributes ‘queen presence and performance’, ‘demography of the
colony’, ‘in-hive products’ and ‘disease, infection and infestation’ could be directly measured in field
conditions across the EU, whereas ‘behaviour and physiology’ is mainly assessed through experimental
studies. Analysing the resource providing unit, in particular land cover/use, of a honeybee colony is
very important when assessing its health status, but tools are currently lacking that could be used at
apiary level in field surveys across the EU. Data on ‘beekeeping management practices’ and
‘environmental drivers’ can be collected via questionnaires and available databases, respectively. The
capacity to provide pollination services is regarded as an indication of a healthy colony, but it is
assessed only in relation to the provision of honey because technical limitations hamper the
assessment of pollination as regulating service (e.g. to pollinate wild plants) in field surveys across the
EU. Integrating multiple attributes of honeybee health, for instance, via a Health Status Index, is
required to support a holistic assessment. Examples are provided on how the toolbox could be used by
different stakeholders. Continued interaction between the Member State organisations, the EU
Reference Laboratory and EFSA is required to further validate methods and facilitate the efficient use
of precise and accurate bee health data that are collected by many initiatives throughout the EU.info:eu-repo/semantics/publishedVersio
Urgent advice on lumpy skin disease EFSA Panel on Animal Health and Welfare
In order to assess the effects on disease spread and persistence of partial stamping out of only
clinically affected animals in holdings where the presence of lumpy skin disease has been confirmed,
against total stamping-out policy of infected herds coupled with vaccination, a mathematical model for
the transmission of LSDV between farms was developed and different scenarios explored. According to
the model, vaccination has a greater impact in reducing LSDV spread than any culling policy, even
when low vaccination effectiveness is considered. When vaccination is evenly applied so that 95% of
the farms are vaccinated with 75% of vaccinated animals effectively protected, then total stamping out
and partial stamping out result in a similar probability of eradicating the infection. When no vaccination
is applied or when vaccination has a lower effectiveness (e.g. 40%), the probability of eradication is
higher when total stamping out is performed as compared to partial stamping out. In general, partial
stamping out results in limited increase of the number of farms affected as compared to total stamping
out. Independently of the culling interventions applied in the model, vaccination was most effective in
reducing LSDV spread if protection had already been developed at the time of virus entry, followed by
protection of herds after virus entry. No vaccination is the least effective option in reducing LSDV
spread. In order to reach the above described effects, it is necessary to implement vaccination of the
entire susceptible population in regions at risk for LSDV introduction or affected by LSDV in order to
minimise the number of outbreaks, and high animal- and farm-level vaccination coverage should be
achieved. Farmers and veterinarians should be trained in the clinical identification of LSD in order to
reduce underreporting, and the effectiveness of partial stamping out should be evaluated under field
conditions.info:eu-repo/semantics/publishedVersio
Guidance on the assessment criteria for applications for new or modified stunning methods regarding animal protection at the time of killing
This guidance defines the process for handling applications on new or modified stunning methods and the parameters that will be assessed by the EFSA Animal Health and Welfare (AHAW) Panel. The applications, received through the European Commission, should contain administrative information, a checklist of data to be submitted and a technical dossier. The dossier should include two or more studies (in laboratory and slaughterhouse conditions) reporting all parameters and methodological aspects that are indicated in the guidance. The applications will first be scrutinised by the EFSA’s Applications Desk (APDESK) Unit for verification of the completeness of the data submitted for the risk assessment of the stunning method. If the application is considered not valid, additional information may be requested from the applicant. If considered valid, it will be subjected to assessment phase 1 where the data related to parameters for the scientific evaluation of the stunning method will be examined by the AHAW Panel. Such parameters focus on the stunning method and the outcomes of interest, i.e. immediate onset of unconsciousness or the absence of avoidable pain, distress and suffering until the loss of consciousness and duration of the unconsciousness (until death). The applicant should also propose methodologies and results to assess the equivalence with existing stunning methods in terms of welfare outcomes. Applications passing assessment phase 1 will be subjected to the following phase 2 which will be carried out by the AHAW Panel and focuses on the animal welfare risk assessment. In this phase, the Panel will assess the outcomes, conclusions and discussion proposed by the applicant. The results of the assessment will be published in a scientific opinion.info:eu-repo/semantics/publishedVersio
Guidance on the assessment criteria for applications for new or modified stunning methods regarding animal protection at the time of killing
This guidance defines the process for handling applications on new or modified stunning methods and the parameters that will be assessed by the EFSA Animal Health and Welfare (AHAW) Panel. The applications, received through the European Commission, should contain administrative information, a checklist of data to be submitted and a technical dossier. The dossier should include two or more studies (in laboratory and slaughterhouse conditions) reporting all parameters and methodological aspects that are indicated in the guidance. The applications will first be scrutinised by the EFSA’s Applications Desk (APDESK) Unit for verification of the completeness of the data submitted for the risk assessment of the stunning method. If the application is considered not valid, additional information may be requested from the applicant. If considered valid, it will be subjected to assessment phase 1 where the data related to parameters for the scientific evaluation of the stunning method will be examined by the AHAW Panel. Such parameters focus on the stunning method and the outcomes of interest, i.e. immediate onset of unconsciousness or the absence of avoidable pain, distress and suffering until the loss of consciousness and duration of the unconsciousness (until death). The applicant should also propose methodologies and results to assess the equivalence with existing stunning methods in terms of welfare outcomes. Applications passing assessment phase 1 will be subjected to the following phase 2 which will be carried out by the AHAW Panel and focuses on the animal welfare risk assessment. In this phase, the Panel will assess the outcomes, conclusions and discussion proposed by the applicant. The results of the assessment will be published in a scientific opinion.info:eu-repo/semantics/publishedVersio
Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429):Ebola virus disease
Abstract Koi herpes virus (KHV) disease has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of KHV disease to be listed, Article 9 for the categorisation of KHV disease according to disease prevention and control rules as in Annex IV and Article 8 on the list of animal species related to KHV disease. The assessment has been performed following a methodology composed of information collection and compilation, expert judgement on each criterion at individual and, if no consensus was reached before, also at collective level. The output is composed of the categorical answer, and for the questions where no consensus was reached, the different supporting views are reported. Details on the methodology used for this assessment are explained in a separate opinion. According to the assessment performed, it is inconclusive whether KHV disease can be considered eligible to be listed for Union intervention as laid down in Article 5(3) of the AHL because there was no full consensus on the criterion 5 A(v). Consequently, the assessment on compliance of KHV disease with the criteria as in Annex IV of the AHL, for the application of the disease prevention and control rules referred to in Article 9(1) is also inconclusive, as well as which animal species can be considered to be listed for KHV disease according to Article 8(3) of the AHL
Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429):bovine tuberculosis
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