5,238 research outputs found
The Lyman Continuum Escape Survey: Ionizing Radiation from [O III]-Strong Sources at a Redshift of 3.1
We present results from the LymAn Continuum Escape Survey (LACES), a Hubble
Space Telescope (HST) program designed to characterize the ionizing radiation
emerging from a sample of Lyman alpha emitting galaxies at redshift . As many show intense [O III] emission characteristic of
star-forming galaxies, they may represent valuable low redshift analogs of
galaxies in the reionization era. Using HST Wide Field Camera 3 / UVIS
to image Lyman continuum emission, we investigate the escape fraction of
ionizing photons in this sample. For 61 sources, of which 77% are
spectroscopically confirmed and 53 have measures of [O III] emission, we detect
Lyman continuum leakage in 20%, a rate significantly higher than is seen in
individual continuum-selected Lyman break galaxies. We estimate there is a 98%
probability that of our detections could be affected by foreground
contamination. Fitting multi-band spectral energy distributions (SEDs) to take
account of the varying stellar populations, dust extinctions and metallicities,
we derive individual Lyman continuum escape fractions corrected for foreground
intergalactic absorption. We find escape fractions of 15 to 60% for individual
objects, and infer an average 20% escape fraction by fitting composite SEDs for
our detected samples. Surprisingly however, even a deep stack of those sources
with no individual detections provides a stringent upper limit on the
average escape fraction of less than 0.5%. We examine various correlations with
source properties and discuss the implications in the context of the popular
picture that cosmic reionization is driven by such compact, low metallicity
star-forming galaxies.Comment: 26 pages, 16 figures, accepted for publication in Ap
Asymptotic enumeration of incidence matrices
We discuss the problem of counting {\em incidence matrices}, i.e. zero-one
matrices with no zero rows or columns. Using different approaches we give three
different proofs for the leading asymptotics for the number of matrices with
ones as . We also give refined results for the asymptotic
number of incidence matrices with ones.Comment: jpconf style files. Presented at the conference "Counting Complexity:
An international workshop on statistical mechanics and combinatorics." In
celebration of Prof. Tony Guttmann's 60th birthda
The azimuth structure of nuclear collisions -- I
We describe azimuth structure commonly associated with elliptic and directed
flow in the context of 2D angular autocorrelations for the purpose of precise
separation of so-called nonflow (mainly minijets) from flow. We extend the
Fourier-transform description of azimuth structure to include power spectra and
autocorrelations related by the Wiener-Khintchine theorem. We analyze several
examples of conventional flow analysis in that context and question the
relevance of reaction plane estimation to flow analysis. We introduce the 2D
angular autocorrelation with examples from data analysis and describe a
simulation exercise which demonstrates precise separation of flow and nonflow
using the 2D autocorrelation method. We show that an alternative correlation
measure based on Pearson's normalized covariance provides a more intuitive
measure of azimuth structure.Comment: 27 pages, 12 figure
Bromine measurements in ozone depleted air over the Arctic Ocean
In situ measurements of ozone, photochemically active bromine compounds, and other trace gases over the Arctic Ocean in April 2008 are used to examine the chemistry and geographical extent of ozone depletion in the arctic marine boundary layer (MBL). Data were obtained from the NOAA WP-3D aircraft during the Aerosol, Radiation, and Cloud Processes affecting Arctic Climate (ARCPAC) study and the NASA DC-8 aircraft during the Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) study. Fast (1 s) and sensitive (detection limits at the low pptv level) measurements of BrCl and BrO were obtained from three different chemical ionization mass spectrometer (CIMS) instruments, and soluble bromide was measured with a mist chamber. The CIMS instruments also detected Br2. Subsequent laboratory studies showed that HOBr rapidly converts to Br2 on the Teflon instrument inlets. This detected Br2 is identified as active bromine and represents a lower limit of the sum HOBr + Br2. The measured active bromine is shown to likely be HOBr during daytime flights in the arctic. In the MBL over the Arctic Ocean, soluble bromide and active bromine were consistently elevated and ozone was depleted. Ozone depletion and active bromine enhancement were confined to the MBL that was capped by a temperature inversion at 200–500 m altitude. In ozone-depleted air, BrO rarely exceeded 10 pptv and was always substantially lower than soluble bromide that was as high as 40 pptv. BrCl was rarely enhanced above the 2 pptv detection limit, either in the MBL, over Alaska, or in the arctic free troposphere
Atomic Carbon in Galaxies
We present new measurements of the ground state fine-structure line of atomic
carbon at 492 GHz in a variety of nearby external galaxies, ranging from spiral
to irregular, interacting and merging types. In comparison with CO(1-0), the
CI(1-0) intensity stays fairly comparable in the different environments, with
an average value of the ratio of the line integrated areas in Kkm/s of
CI(1-0)/CO(1-0) = 0.2 +/- 0.2. However, some variations can be found within
galaxies, or between galaxies. Relative to CO lines, CI(1-0) is weaker in
galactic nuclei, but stronger in disks, particularly outside star forming
regions. Also, in NGC 891, the CI(1-0) emission follows the dust continuum at
1.3mm extremely well along the full length of the major axis where molecular
gas is more abundant than atomic gas. Atomic carbon therefore appears to be a
good tracer of molecular gas in external galaxies, possibly more reliable than
CO. Atomic carbon can contribute significantly to the thermal budget of
interstellar gas. Cooling due to C and CO amounts typically to 2 x 10^{-5} of
the FIR continuum or 5% of the CII line. However, C and CO cooling reaches 30%
of the gas total, in Ultra Luminous InfraRed Galaxies, where CII is abnormally
faint. Together with CII/FIR, the emissivity ratio CI(1-0)/FIR can be used as a
measure of the non-ionizing UV radiation field in galaxies.Comment: 26 pages, 8 figure
RNA-binding protein CPEB1 remodels host and viral RNA landscapes.
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in widespread alternative splicing (AS), shortening of 3' untranslated regions (3' UTRs) and lengthening of poly(A)-tails in host gene transcripts. We found that the host RNA-binding protein CPEB1 was highly induced after infection, and ectopic expression of CPEB1 in noninfected cells recapitulated infection-related post-transcriptional changes. CPEB1 was also required for poly(A)-tail lengthening of viral RNAs important for productive infection. Strikingly, depletion of CPEB1 reversed infection-related cytopathology and post-transcriptional changes, and decreased productive HCMV titers. Host RNA processing was also altered in herpes simplex virus-2 (HSV-2)-infected cells, thereby indicating that this phenomenon might be a common occurrence during herpesvirus infections. We anticipate that our work may serve as a starting point for therapeutic targeting of host RNA-binding proteins in herpesvirus infections
Probing for Exoplanets Hiding in Dusty Debris Disks: Disk Imaging, Characterization, and Exploration with HST/STIS Multi-Roll Coronagraphy
Spatially resolved scattered-light images of circumstellar (CS) debris in
exoplanetary systems constrain the physical properties and orbits of the dust
particles in these systems. They also inform on co-orbiting (but unseen)
planets, systemic architectures, and forces perturbing starlight-scattering CS
material. Using HST/STIS optical coronagraphy, we have completed the
observational phase of a program to study the spatial distribution of dust in
ten CS debris systems, and one "mature" protoplanetrary disk all with HST
pedigree, using PSF-subtracted multi-roll coronagraphy. These observations
probe stellocentric distances > 5 AU for the nearest stars, and simultaneously
resolve disk substructures well beyond, corresponding to the giant planet and
Kuiper belt regions in our Solar System. They also disclose diffuse very
low-surface brightness dust at larger stellocentric distances. We present new
results inclusive of fainter disks such as HD92945 confirming, and better
revealing, the existence of a narrow inner debris ring within a larger diffuse
dust disk. Other disks with ring-like sub-structures, significant asymmetries
and complex morphologies include: HD181327 with a posited spray of ejecta from
a recent massive collision in an exo-Kuiper belt; HD61005 suggested interacting
with the local ISM; HD15115 & HD32297, discussed also in the context of
environmental interactions. These disks, and HD15745, suggest debris system
evolution cannot be treated in isolation. For AU Mic's edge-on disk,
out-of-plane surface brightness asymmetries at > 5 AU may implicate one or more
planetary perturbers. Time resolved images of the MP Mus proto-planetary disk
provide spatially resolved temporal variability in the disk illumination. These
and other new images from our program enable direct inter-comparison of the
architectures of these exoplanetary debris systems in the context of our own
Solar System.Comment: 109 pages, 43 figures, accepted for publication in the Astronomical
Journa
Exploring differences in adverse symptom event grading thresholds between clinicians and patients in the clinical trial setting
Symptomatic adverse event (AE) monitoring is essential in cancer clinical trials to assess patient safety, as well as inform decisions related to treatment and continued trial participation. As prior research has demonstrated that conventional concordance metrics (e.g., intraclass correlation) may not capture nuanced aspects of the association between clinician and patient-graded AEs, we aimed to characterize differences in AE grading thresholds between doctors (MDs), registered nurses (RNs), and patients using the Bayesian Graded Item Response Model (GRM)
A New, Bright, Short-Period, Emission Line Binary in Ophiuchus
The 11th magnitude star LS IV -08 3 has been classified previously as an OB
star in the Luminous Stars survey, or alternatively as a hot subdwarf. It is
actually a binary star. We present spectroscopy, spectroscopic orbital
elements, and time series photometry, from observations made at the Kitt Peak
National Observatory 2.1m, Steward Observatory 2.3m, MDM Observatory 1.3m and
2.4m, Hobby-Eberly 9.2m, and Michigan State University 0.6m telescopes. The
star exhibits emission of varying strength in the cores of H and He I
absorption lines. Emission is also present at 4686 Angstroms (He II) and near
4640/4650 Angstroms (N III/C III). Time-series spectroscopy collected from 2005
July to 2007 June shows coherent, periodic radial velocity variations of the
H-alpha line, which we interpret as orbital motion with a period of
0.1952894(10) days. High-resolution spectra show that there are two emission
components, one broad and one narrow, moving in antiphase, as might arise from
an accretion disk and the irradiated face of the mass donor star. Less
coherent, low-amplitude photometric variability is also present on a timescale
similar to the orbital period. Diffuse interstellar bands indicate considerable
reddening, which however is consistent with a distance of ~100-200 pc. The star
is the likely counterpart of a weak ROSAT X-ray source, whose properties are
consistent with accretion in a cataclysmic variable (CV) binary system. We
classify LS IV -08 3 as a new member of the UX UMa subclass of CV stars.Comment: To be published in AJ, 16 pages, 6 figures. Uses AAS Late
The CASSOWARY spectroscopy survey: a new sample of gravitationally lensed galaxies in SDSS
Bright gravitationally lensed galaxies provide our most detailed view of galaxies at high redshift. The very brightest (r < 21) systems enable high spatial and spectral resolution measurements, offering unique constraints on the outflow energetics, metallicity gradients and stellar populations in high-redshift galaxies. Yet as a result of the small number of ultrabright z ≃ 2 lensed systems with confirmed redshifts, most detailed spectroscopic studies have been limited in their scope. With the goal of increasing the number of bright lensed galaxies available for detailed follow-up, we have undertaken a spectroscopic campaign targeting wide separation (≳3 arcsec) galaxy–galaxy lens candidates within the Sloan Digital Sky Survey (SDSS). Building on the earlier efforts of our Cambridge and Sloan Survey Of Wide Arcs in Thesky survey, we target a large sample of candidate galaxy–galaxy lens systems in SDSS using a well-established search algorithm which identifies blue arc-like structures situated around luminous red galaxies. In this paper, we present a new redshift catalogue containing 29 lensed sources in SDSS confirmed through spectroscopic follow-up of candidate galaxy–galaxy lens systems. Included in this new sample are two of the brightest galaxies (r = 19.6 and 19.7) known at z ≃ 2, a low metallicity (12 + log (O/H) ≃ 8.0) extreme nebular line emitting galaxy at z = 1.43, and numerous systems for which detailed follow-up will be possible. The source redshifts span 0.9 < z < 2.5 (median redshift of 1.9), and their optical magnitudes are in the range 19.6 ≲ r ≲ 22.3. We present a brief source-by-source discussion of the spectroscopic properties extracted from our confirmatory spectra and discuss some initial science results. Preliminary lens modelling reveals average source magnifications of 5–10 times. With more than 50 gravitationally lensed z ≳ 1 galaxies now confirmed within SDSS, it will soon be possible for the first time to develop generalized conclusions from detailed spectroscopic studies of the brightest lensed systems at high redshift
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