154 research outputs found

    The religious field and the path-dependent transformation of popular politics in the Anglo-American world, 1770-1840

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    This article examines the formative influence of the organizational field of religion on emerging modern forms of popular political mobilization in Britain and the United States in the early nineteenth century when a transition towards enduring campaigns of extended geographical scale occurred. The temporal ordering of mobilization activities reveals the strong presence of religious constituencies and religious organizational models in the mobilizatory sequences that first instituted a mass-produced popular politics. Two related yet analytically distinct generative effects of the religious field can be discerned. First, in both cases the transition toward modern forms of popular mobilization was driven by the religious institutionalization of organizational forms of centralized voluntarism that facilitated extensive collective action. Second, the adoption of different varieties of the same organizational forms led to important divergences. The spread in the United States of societies for moral reformation—in contrast to their non-survival in Britain—steered popular politics there towards a more moralistic framing of public issues. These findings indicate the importance of the organizational field of religion for the configuration of modern forms of popular collective action and confirm the analytical importance of religion’s organizational aspects for the study of collective action

    Beyond and against capitalism: abolitionism and the moral dimension of humanitarian practice

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    How do we understand the origins of modern humanitarianism and what can these origins tell us about the study of humanitarianism in general? Here I revisit a critical juncture of the formation of modern humanitarianism, the late 18th-century movement to abolish the British slave trade, through the lens of a prevailing paradigm that has explained it as deriving from the logic of capitalist development. A closer look at this early phase of abolitionism within its historical context reveals the implausibility of the economy as the most salient explanatory factor for the origin and success of the abolitionist project. Instead, this project emerged at the interstices of a complex causal entanglement between the areas of economic and moral action. I conclude by drawing out the larger implications of this historical complexity for the study of humanitarianism at large. The complex causal dynamics that produced early abolitionism urges us to be more attentive to the manifold forms of humanitarian practice and to situate them in a proper causal context instead of assuming that humanitarianism is an epiphenomenal manifestation of allegedly deeper structural forces, such as the economy. Reversing this assumption and directing attention to the casual influence of humanitarianism on other areas of social life opens up a promising field of scholarly inquiry

    Activist Religion, Empire, and the Emergence of Modern Long-Distance Advocacy Networks

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    Considering long-distance advocacy as a distinctive institution of European modernity, the article examines the genesis and history of networks engaged in political action on behalf of distant others. Ever since the beginnings of European expansion overseas in the sixteenth century, such networks have originated from a persistent pattern of radicalization of religious actors against rival networks within the context of empire. In the late eighteenth century, the very same processes led to the establishment of modern forms of long-distance advocacy, with the international movement against colonial slavery and the slave trade. Throughout, long-distance advocacy was initiated and carried out by distinctively reformist and activist religious organizations within Catholicism and Protestantism. These findings highlight the importance of religious organizations in the imperial context for the configuration of modern forms of political activism

    Predicting In Vivo Transcription Factor Occupancy from In Vitro Binding

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    <p>The spatial pattern of transcription factor (TF) binding and the level of TF occupancy at individual sites across the genome determine how a TF regulates its targets. Consequently, predicting the location and level of TF binding genome-wide is of great importance and has received much attention recently. Protein-binding microarray (PBM) technology has become the golden standard for studying TF-DNA interactions in vitro, while Chromatin Immunoprecipitation followed by DNA Sequencing (ChIP-seq) is the standard method for inferring TF binding in vivo. However, direct interpretation of in vitro results in an in vivo context is challenging and to-date remains scarce. In this study, we focus on the E2F family of paralogous TFs, whose mode of binding to DNA has been controversial. Previous studies have shown that E2F factors bind to the TTTSSCGCG motif, where S can be a C or a G. Still, only a small fraction of in vivo targets are reported to contain this motif, hinting at indirect recruitment of the protein. We observed that genomic occupancy of E2F factors directly correlates with their in vitro binding affinities. By using data from universal PBM experiments, we show that E2F factors likely bind to DNA through direct sequence recognition and not through cofactor interaction. Furthermore, we developed a kinetic binding model using the PBM data to describe competition between different members of the E2F family and successfully distinguished between their unique targets. Overall, these results demonstrate how the straightforward and simple in vitro PBM experiments can be used for inferring the complex in vivo landscape of TF binding and elucidate the mechanism of E2F-DNA interaction.</p>Thesi

    INFLUENCE OF THE SEA-SIDE RESORT FACTORS UPON FIBRINOLYTIC ACTIVITY OF PATIENTS WITH HYPERTENSION

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    INVESTIGATING ADAPTATIONAL RESERVE CHANGES IN HYPERTENSION PATIENTS DURING SEASIDE SANATORIAL TREATMENT

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    Ideias versus redes sociais: ativismo à distância na Inglaterra do século XVIII

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    Quais são as fontes históricas das mobilizações em torno de questões distantes - uma característica típica da modernidade? Este artigo examina a dinâmica social que produziu os primeiros casos de campanhas sustentadas em torno de questões distantes na Grã-Bretanha do século XVIII. O surgimento dessas campanhas é muitas vezes entendido como determinado pela ascensão nesse período de novas ideologias de compaixão humanitária. Para testar o papel dessas ideologias, comparo dois conjuntos de campanhas: o impeachment de Warrant Hastings por Edmund Burke e a série de mobilizações religiosas iniciada com o movimento contra o tráfico de escravos colonial. Embora ambos os conjuntos fossem impulsionados por idiomas culturais de preocupação humanitária semelhantes, a iniciativa de Burke falhou em produzir engajamento popular e as campanhas religiosas foram capazes de mobilizar amplas audiências de apoiadores. Essa diferença surpreendente destaca a importância das redes associativas religiosas para o surgimento dos primeiros casos modernos de mobilização em torno de questões distantes.What are the historical sources for mobilizations around distant issues - one of the characteristic features of modernity? This article examines the social dynamics that led to the first sustained campaigns on distant issues in late eighteenth-century Britain. Their emergence is often understood to have been determined by the rise of new ideologies of humanitarian compassion during the period. To test the role of these ideologies, I compare two sets of campaigns: Edmund Burke's impeachment of Warrant Hastings and the series of religious mobilizations initiated with the movement against the colonial slave trade. While both campaigns were driven by similar cultural idioms of humanitarian concern, Burke's initiative failed to produce popular engagement, while the religious campaigns were able to mobilize wide groups of public supporters. This striking difference highlights the importance of religious associational networks for the emergence of the first modern instances of mobilization on distant issues

    HEALTH-RESORT SEASIDE CLIMATOTHERAPY RECONVALESCENT EPIDEMIC HEPATITIS PATIENTS

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    Germination and Early Seedling Growth Characteristics of Arachis hypogaea L. under Salinity (NaCl) Stress

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    Peanut plants (Arachis hypogaea L.) are glycophytes indicating their vulnerability to highly saline soils. The aim of this study was to evaluate the effect of different NaCl concentrations on seed germination characteristics and early seedling growth of peanut seeds of three Bulgarian cultivars - \u27Kremena\u27, \u27Kalina\u27 and \u274389\u27. Four different concentrations of NaCl (50, 100, 150 and 200 mM) were used as treatments and deionized water as control. To determine the salinity tolerance, the data for following germination characteristics - germination energy (%), final germination (%), coefficient of velocity of germination (% day-1), germination rate index and mean germination time (day) and seedling characteristics - shoot and root length (cm), fresh weight (mg plant-1) of shoot and root and dry weight (mg plant-1) of shoot and root were recorded. The Vigor index, coefficients of depression of roots and shoots and salt tolerance index were also calculated. The genotype had the strongest influence on the variance of the root length, while the salinity treatment had the strongest influence on germination energy, coefficient of velocity of germination, germination rate index, mean germination time, length of shoot, fresh weight of shoot and dry weigth of shoot and root. \u27Kremena\u27 was the most tolerant at seedling growth stage, while \u274389\u27 was the most sensitive especially at high levels of salt stress. Principal component (PC) analysis grouped analysed cultivars at different salinity stress according to similarity on the basis of investigated germination and seedling characters in two components in the factor plane
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