345 research outputs found
On the factors causing processing difficulty of multiple-scene displays
Multiplex viewing of static or dynamic scenes is an increasing feature of screen media. Most existing multiplex experiments have examined detection across increasing scene numbers, but currently no systematic evaluation of the factors that might produce difficulty in processing multiplexes exists. Across five experiments we provide such an evaluation. Experiment 1 characterises difficulty in change detection when the number of scenes is increased. Experiment 2 reveals that the increased difficulty across multiple-scene displays is caused by the total amount of visual information accounts for differences in change detection times, regardless of whether this information is presented across multiple scenes, or contained in one scene. Experiment 3 shows that whether quadrants of a display were drawn from the same, or different scenes did not affect change detection performance. Experiment 4 demonstrates that knowing which scene the change will occur in means participants can perform at monoplex level. Finally, Experiment 5 finds that changes of central interest in multiplexed scenes are detected far easier than marginal interest changes to such an extent that a centrally interesting object removal in nine screens is detected more rapidly than a marginally interesting object removal in four screens. Processing multiple-screen displays therefore seems dependent on the amount of information, and the importance of that information to the task, rather than simply the number of scenes in the display. We discuss the theoretical and applied implications of these findings
Behavioral biases when viewing multiplexed scenes:scene structure and frames of reference for inspection
Where people look when viewing a scene has been a much explored avenue of vision research (e.g., see Tatler, 2009). Current understanding of eye guidance suggests that a combination of high and low-level factors influence fixation selection (e.g., Torralba et al., 2006), but that there are also strong biases toward the center of an image (Tatler, 2007). However, situations where we view multiplexed scenes are becoming increasingly common, and it is unclear how visual inspection might be arranged when content lacks normal semantic or spatial structure. Here we use the central bias to examine how gaze behavior is organized in scenes that are presented in their normal format, or disrupted by scrambling the quadrants and separating them by space. In Experiment 1, scrambling scenes had the strongest influence on gaze allocation. Observers were highly biased by the quadrant center, although physical space did not enhance this bias. However, the center of the display still contributed to fixation selection above chance, and was most influential early in scene viewing. When the top left quadrant was held constant across all conditions in Experiment 2, fixation behavior was significantly influenced by the overall arrangement of the display, with fixations being biased toward the quadrant center when the other three quadrants were scrambled (despite the visual information in this quadrant being identical in all conditions). When scenes are scrambled into four quadrants and semantic contiguity is disrupted, observers no longer appear to view the content as a single scene (despite it consisting of the same visual information overall), but rather anchor visual inspection around the four separate “sub-scenes.” Moreover, the frame of reference that observers use when viewing the multiplex seems to change across viewing time: from an early bias toward the display center to a later bias toward quadrant centers
Longitudinal assessment of reflexive and volitional saccades in Niemann-Pick Type C disease during treatment with miglustat
Peer reviewedPublisher PD
Coordinating vision and action in natural behaviour : differences in spatiotemporal coupling in everyday tasks
Peer reviewedPostprin
Looking for trouble:a description of oculomotor search strategies during live CCTV operation
Recent research has begun to address how CCTV operators in the modern control room attempt to search for crime (e.g., Howard et al., 2011). However, an often-neglected element of the CCTV task is that the operators have at their disposal a multiplexed wall of scenes, and a single spot-monitor on which they can select any of these feeds for inspection. Here we examined how 2 trained CCTV operators used these sources of information to search from crime during a morning, afternoon, and night-time shift. We found that they spent surprisingly little time viewing the multiplex wall, instead preferentially spending most of their time searching on the single-scene spot-monitor. Such search must require a sophisticated understanding of the surveilled environment, as the operators must make their selection of which screen to view based on their prediction of where crime is likely to occur. This seems to be reflected in the difference in the screens that they selected to view at different times of the day. For example, night-clubs received close monitoring at night, but were seldom viewed in mid-morning. Such narrowing of search based on a contextual understanding of an environment is not a new idea (e.g., Torralba et al., 2006), and appears to contribute to operator's selection strategy. This research prompts new questions regarding the nature of representation that operators have of their environment, and how they might develop expectation-based search strategies to countermand the demands of the large influx of visual information. Future research should ensure not to neglect examination of operator behavior “in the wild” (Hutchins, 1995a), as such insights are difficult to gain from laboratory based paradigms alone
Weaber Plain aquifer test results
As a part of the environmental planning and approvals process, the state government was required to prepare Groundwater Management and Hydrodynamic Plans. These plans are to address potential issues of salinity and water quality that could result from the development of irrigated agriculture on the Weaber Plain. The Weaber Plain groundwater modelling report (KBR 2010a) identified several options to manage watertables and salinity
Production bores 10WP35PB and 10WP36PB were drilled in the palaeochannel on sites selected from the interpretation of airborne geophysics
Effect of prevention measures on incidence of human listeriosis, France, 1987-1997.
To assess the impact of preventive measures by the food industry, we analyzed food monitoring data as well as trends in the incidence of listeriosis estimated through three independent sources: the National Reference Center of Listeriosis; a laboratory-based active surveillance network; and two consecutive nationwide surveys of public hospital laboratories. From 1987 to 1997, the incidence of listeriosis decreased by an estimated 68%. A substantial reduction in the proportion of Listeria monocytogenes-contaminated products was observed at the retail level. The temporal relationship between prevention measures by the food industry, reduction in L. monocytogenes-contaminated foodstuffs, and reduction in listeriosis incidence suggests a causal relationship and indicates that a substantial part of the reduction in illness is related to prevention efforts
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Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen
OBJECTIVE:
Ibrutinib is an irreversible Bruton tyrosine kinase inhibitor approved for treatment of Waldenstrom macroglobulinemia, chronic lymphocytic leukemia, and mantle cell lymphoma that increases the risk of bleeding among patients. Platelets from ibrutinib-treated patients exhibit deficiencies in collagen-evoked signaling in suspension; however, the significance of this observation and how it relates to bleeding risk is unclear, as platelets encounter immobile collagen in vivo. We sought to clarify the effects of ibrutinib on platelet function to better understand the mechanism underlying bleeding risk.
APPROACH AND RESULTS:
By comparing signaling in suspension and during adhesion to immobilized ligands, we found that the collagen signaling deficiency caused by ibrutinib is milder during adhesion to immobilized collagen. We also found that platelets in whole blood treated with ibrutinib adhered to collagen under arterial shear but formed unstable thrombi, suggesting that the collagen signaling deficiency caused by ibrutinib may not be the predominant cause of bleeding in vivo. However, clot retraction and signaling evoked by platelet adhesion to immobilized fibrinogen were also inhibited by ibrutinib, indicating that integrin αIIbβ3 outside-in signaling is also effected in addition to GPVI signaling. When ibrutinib was combined with the P2Y12 inhibitor, cangrelor, thrombus formation under arterial shear was inhibited additively.
CONCLUSIONS:
These findings suggest that (1) ibrutinib causes GPVI and integrin αIIbβ3 platelet signaling deficiencies that result in formation of unstable thrombi and may contribute toward bleeding observed in vivo and (2) combining ibrutinib with P2Y12 antagonists, which also inhibit thrombus stability, may have a detrimental effect on hemostasis
Object Properties Influence Visual Guidance of Motor Actions
Peer reviewedPublisher PD
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