598 research outputs found

    Introduction to Open Pedagogy

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    Managing Information with Zotero

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    Reference managers help collect, organize, cite, and share research. Zotero is an open-source, providing 300 mb of free, cloud-based storage while leaving you in control of your data. This session will provide hands-on practice with Zotero\u27s basic features

    Conducting a Literature Review

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    Why and how do you start a literature review? Building on the Research Consultations with Subject Librarians and the Zotero introduction, this session will walk through the basic steps of a literature review and provide short, hands-on activities for practice in applying techniques

    Genome -Scale Reconstruction of Metabolic Networks of Lactobacillus casei ATCC 334 and 12A

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    Lactobacillus casei strains are widely used in industry and the utility of this organism in these industrial applications is straindependent. Hence, tools capable of predicting strain specific phenotypes would have utility in the selection of strains forspecific industrial processes. Genome-scale metabolic models can be utilized to better understand genotype-phenotyperelationships and to compare different organisms. To assist in the selection and development of strains with enhancedindustrial utility, genome-scale models for L. casei ATCC 334, a well characterized strain, and strain 12A, a corn silage isolate,were constructed. Draft models were generated from RAST genome annotations using the Model SEED database and refined by evaluating ATP generating cycles, mass-and-charge-balances of reactions, and growth phenotypes. After the validation process was finished, we compared the metabolic networks of these two strains to identify metabolic, genetic and ortholog differences that may lead to different phenotypic behaviors. We conclude that the metabolic capabilities of the two networks are highly similar. The L. casei ATCC 334 model accounts for 1,040 reactions, 959 metabolites and 548 genes, while the L. casei 12A model accounts for 1,076 reactions, 979 metabolites and 640 genes. The developed L. casei ATCC 334 and 12A metabolic models will enable better understanding of the physiology of these organisms and be valuable tools in the development and selection of strains with enhanced utility in a variety of industrial applications

    Prospectus, October 7, 1981

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    BOB BROWN, 55, DIES; News In Brief; Library open until 10 p.m.; Students play in tourneys; Christian Fellowship plans month; Guides needed; Honor society seeks students; Ski Club plans trips; Editor wonders…: Are you alive, Parkland?; PACT programs held; Artist presents workshop; Club selling hot dogs; More tips on shopping; Workshop offered on business; Classifieds; Song simple, yet good; Dunaway stars in new movie; \u27Journey\u27 not worth trip; Talk, learn through your TV in future; PATH holds meeting; Teacher market opening up; Skater returns, playing Tuesday; Children as thieves?: Even kids are dishonest; Golf team wins conference; VB team gives erratic show; Hearns/Leonard fight is reviewed; Sports Notes; Explore the humanities; Fast Freddy is back again; Fast Freddy Contest; Music offers something for everyonehttps://spark.parkland.edu/prospectus_1981/1010/thumbnail.jp

    Analysis of the Lactobacilluscasei supragenome and its influence in species evolution and lifestyle adaptation

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    The broad ecological distribution of L. casei makes it an insightful subject for research on genome evolution and lifestyle adaptation. To explore evolutionary mechanisms that determine genomic diversity of L. casei, we performed comparative analysis of 17 L. casei genomes representing strains collected from dairy, plant, and human sources. Results Differences in L. casei genome inventory revealed an open pan-genome comprised of 1,715 core and 4,220 accessory genes. Extrapolation of pan-genome data indicates L. casei has a supragenome approximately 3.2 times larger than the average genome of individual strains. Evidence suggests horizontal gene transfer from other bacterial species, particularly lactobacilli, has been important in adaptation of L. casei to new habitats and lifestyles, but evolution of dairy niche specialists also appears to involve gene decay. Conclusions Genome diversity in L. casei has evolved through gene acquisition and decay. Acquisition of foreign genomic islands likely confers a fitness benefit in specific habitats, notably plant-associated niches. Loss of unnecessary ancestral traits in strains collected from bacterial-ripened cheeses supports the hypothesis that gene decay contributes to enhanced fitness in that niche. This study gives the first evidence for a L. casei supragenome and provides valuable insights into mechanisms for genome evolution and lifestyle adaptation of this ecologically flexible and industrially important lactic acid bacterium. Additionally, our data confirm the Distributed Genome Hypothesis extends to non-pathogenic, ecologically flexible species like L. casei

    Studying and supporting collaborative care processes

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    Paper presented at the Human Factors & Ergonomics Society (HFES 2005), June 13, 2005.In patient care today, teams of practitioners from various disciplines must coordinate their efforts in order to deliver care successfully. Frontline nurses and physicians must interact with social workers, therapists, physician assistants, nurse practitioners, and others to develop and carry out coordinated plans of care. Also, clinical team members must communicate with patients and their families in language that can be understood and acted upon. In support of these goals, JCAHO standards require patient care to be planned and provided in an interdisciplinary, collaborative manner. As hospital units develop processes for collaborative care in complex environments such as post-surgery and critical care units, it is important to understand what constitutes success for these processes and how they can be enabled and supported. This report documents a series of field visits and simulations designed to observe, videotape, and interview collaborative care team members, patients, and family members engaged in varying forms of collaborative practice. This ongoing research is being conducted by a multi-disciplinary team of medical and social scientists with a shared goal of studying and supporting collaborative care processes

    Communications analysis of the concord collaborative care model

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    Presentation given at the 2005 Safety Across High-Consequence Industries Conference ,SAHI 2005, Saint Louis, MO. Retrieved July 18, 2007 from http://www.cis.drexel.edu/faculty/gerry/pub/sahi2005.pdf

    AI ATAC 1: An Evaluation of Prominent Commercial Malware Detectors

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    This work presents an evaluation of six prominent commercial endpoint malware detectors, a network malware detector, and a file-conviction algorithm from a cyber technology vendor. The evaluation was administered as the first of the Artificial Intelligence Applications to Autonomous Cybersecurity (AI ATAC) prize challenges, funded by / completed in service of the US Navy. The experiment employed 100K files (50/50% benign/malicious) with a stratified distribution of file types, including ~1K zero-day program executables (increasing experiment size two orders of magnitude over previous work). We present an evaluation process of delivering a file to a fresh virtual machine donning the detection technology, waiting 90s to allow static detection, then executing the file and waiting another period for dynamic detection; this allows greater fidelity in the observational data than previous experiments, in particular, resource and time-to-detection statistics. To execute all 800K trials (100K files ×\times 8 tools), a software framework is designed to choreographed the experiment into a completely automated, time-synced, and reproducible workflow with substantial parallelization. A cost-benefit model was configured to integrate the tools' recall, precision, time to detection, and resource requirements into a single comparable quantity by simulating costs of use. This provides a ranking methodology for cyber competitions and a lens through which to reason about the varied statistical viewpoints of the results. These statistical and cost-model results provide insights on state of commercial malware detection

    The Lantern Vol. 68, No. 1, Fall 2000

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    • In Attempting to Imitate J. Agard (III) • Headstones • Calligraphy Grace • Fifty Years • Morning • The Millstone • Quick Stop-Off • Jesus Wept (SuperBuick Bodybag) • Just a God • Amy • Silver Doubloons • Ogbanje • Left Behind • Asymmetrical Smile • Sundays • Pie in the Sky • No Surprises • Bill Gooden\u27s Son • Downcast Eyes Meet Tablecloth • Wetlands • Desperate Actions • Receiving End • A Pack of Matches • Coffeehttps://digitalcommons.ursinus.edu/lantern/1157/thumbnail.jp
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