Risky Business: Sustainability and Industrial Land Use across Seattle’s Gentrifying Riskscape

This paper examines the spatial and temporal trajectories of Seattle’s industrial land use restructuring and the shifting riskscape in Seattle, WA, a commonly recognized urban model of sustainability. Drawing on the perspective of sustainability as a conflicted process, this research explored the intersections of urban industrial and nonindustrial land use planning, gentrification, and environmental injustice. In the first part of our research, we combine geographic cluster analysis and longitudinal air toxic emission comparisons to quantitatively investigate socioeconomic changes in Seattle Census block-groups between 1990, 2000, and 2009 coupled with measures of pollution volume and its relative potential risk. Second, we qualitatively examine Seattle’s historical land use policies and planning and the growing tension between industrial and nonindustrial land use. The gentrification, green cities, and growth management conflicts embedded within sustainability/livability lead to pollution exposure risk and socioeconomic vulnerability converging in the same areas and reveal one of Seattle’s significant environmental challenges. Our mixed-method approach can guide future urban sustainability studies to more effectively examine the connections between land use planning, industrial displacement, and environmental injustice. Our results also help sustainable development practitioners recognize that a more just sustainability in Seattle and beyond will require more planning and policy attention to mitigate obscured industrial land use conflicts

The Compression of Dark Matter Halos by Baryonic Infall

The initial radial density profiles of dark matter halos are laid down by gravitational collapse in hierarchical structure formation scenarios and are subject to further compression as baryons cool and settle to the halo centers. We here describe an explicit implementation of the algorithm, originally developed by Young, to calculate changes to the density profile as the result of adiabatic infall in a spherical halo model. Halos with random motion are more resistant to compression than are those in which random motions are neglected, which is a key weakness of the simple method widely employed. Young's algorithm results in density profiles in excellent agreement with those from N-body simulations. We show how the algorithm may be applied to determine the original uncompressed halos of real galaxies, a step which must be computed with care in order to enable a confrontation with theoretical predictions from theories such as LCDM.Comment: Revised version for ApJ. 8 pages, 8 figures, latex uses emulateap

Optimized fishing through periodically harvested closures

1. Periodically harvested closures (PHCs) are a traditional form of fisheries management that improve fishing efficiency during harvests, partly by reducing fish wariness to fishers during closed periods. However, whether PHCs also result in high yields and healthy marine ecosystems is unknown, even as PHCs are being promoted as a culturally appropriate management tool in the Indo-Pacific.2. We integrated field-derived estimates of change in fish wariness into a bioeconomic fisheries model to quantify to what degree PHCs can maximize harvest efficiency, fisheries yield and fish stock biomass.3. Our model indicated that PHCs that had a closure period of one to a few years between a single pulse harvest were able to generate equivalent fisheries yield and stock biomass levels, with greater harvest efficiency than was able to be achieved using permanent closures and other fisheries management tools.4. Fish life-history traits had little impact on the optimality of PHCs in maximizing the triple objective of harvest efficiency, fisheries yield and stock abundance, with overfishing similarly having little effect at anything under extreme levels. Under moderate overfishing, there was a trade-off between PHCs, which maximised harvest efficiency, and no-take permanent closures that maximised yield. However, the former outweighed the latter, and only at extreme levels of overfishing, where stock was reduced to < 18 % of unfished biomass, were permanent closures favoured over PHCs

The Delay of Population III Star Formation by Supersonic Streaming Velocities

It has recently been demonstrated that coherent relative streaming velocities of order 30 km / s between dark matter and gas permeated the universe on scales below a few Mpc directly after recombination. We here use a series of high-resolution moving-mesh calculations to show that these supersonic motions significantly influence the virialization of the gas in minihalos, and delay the formation of the first stars. As the gas streams into minihalos with bulk velocities around 1 km / s at z ~ 20, the additional momentum and energy input reduces the gas fractions and central densities of the halos, increasing the typical virial mass required for efficient cooling by a factor of three, and delaying Population III star formation by dz ~ 4. Since the distribution of the magnitude of the streaming velocities is narrowly peaked around a non-negligible value, this effect is important in most regions of the universe. As a consequence, the increased minimum halo mass implies a reduction of the absolute number of minihalos that can be expected to cool and form Population III stars by up to an order of magnitude. We further find that the streaming velocities increase the turbulent velocity dispersion of the minihalo gas, which could affect its ability to fragment and hence alter the mass function of the first stars.Comment: 6 pages, 5 figures, accepted for publication in Ap

Detection of bovine inflammatory cytokines IL-1β, IL-6, and TNF-α with a multiplex electrochemiluminescent assay platform

Commercially available bovine-specific assays are limited in number, and multiplex assays for this species are rare. Our objective was to develop a multiplex assay for the bovine inflammatory cytokines IL-1β, IL-6, and TNFα using the Meso Scale Discovery U-PLEX platform. Do-It-Yourself ELISA kits that contained polyclonal antibodies, both unlabeled and biotinylated, and the specific recombinant bovine cytokine standard, were purchased for each of these three cytokines. The biotinylated antibodies were coupled to linkers that bind to specific locations within each well of the U-PLEX plate. Unique linkers were used for each of the cytokines. The unlabeled antibodies were conjugated with electrochemiluminescent labels to serve as detection antibodies. Each cytokine assay was optimized individually prior to performing an optimization on the multiplex assay containing reagents for all three cytokines. To calculate cytokine concentrations, standard curves were developed using the recombinant cytokines and were run concurrently on each plate. Standard curves for IL-1β and TNF-α were run at concentrations ranging from 0 to 50,000 pg/mL, and for IL-6 from 0 to 10,000 pg/mL. The average lowest level of detection concentration measured by the standard curves were 5.3 pg/mL, 0.92 pg/mL, and 22.34 pg/mL for IL-1β, IL-6, and TNF-α respectively, as determined by data from seven plates containing bovine plasma samples from a combination of healthy and diseased cattle. The U-PLEX platform was a viable means to develop custom analyte- and species-specific multiplex assays using privately developed or purchased sets of commercially available reagents

Testing the Hypothesis of Modified Dynamics with Low Surface Brightness Galaxies and Other Evidence

The rotation curves of low surface brightness galaxies provide a unique data set with which to test alternative theories of gravitation over a large dynamic range in size, mass, surface density, and acceleration. Many clearly fail, including any in which the mass discrepancy appears at a particular length-scale. One hypothesis, MOND [Milgrom 1983, ApJ, 270, 371], is consistent with the data. Indeed, it accurately predicts the observed behavior. We find no evidence on any scale which clearly contradicts MOND, and a good deal which supports it.Comment: Accepted for publication in the Astrophysical Journal. 35 pages AAStex + 9 figures. This result surprised the bejeepers out of us, to

Opportunities and constraints for implementing integrated land–sea management on islands

Despite a growing body of literature on integrated land-sea management (ILSM), very little critical assessment has been conducted in order to evaluate ILSM in practice on island systems. Here we develop indicators for assessing 10 integrated island management principles and evaluate the performance of planning and implementation in four island ILSM projects from the tropical Pacific across different governance structures. We find that where customary governance is still strongly respected and enabled through national legislation, ILSM in practice can be very effective at restricting access and use according to fluctuations in resource availability. However, decision-making under customary governance systems may be vulnerable to mismanagement. Government-led ILSM processes have the potential to design management actions that address the spatial scale of ecosystem processes and threats within the context of national policy and legislation, but may not fully capture broad stakeholder interests, and implementation may be poorly coordinated across highly dispersed island archipelagos. Private sector partnerships offer unique opportunities for resourcing island ILSM, although these are highly likely to be geared towards private sector interests that may change in the future and no longer align with community and/or national objectives. We identify consistent challenges that arise during island ILSM planning and implementation and offer recommendations for improvement

The Formation of the First Massive Black Holes

Supermassive black holes (SMBHs) are common in local galactic nuclei, and SMBHs as massive as several billion solar masses already exist at redshift z=6. These earliest SMBHs may grow by the combination of radiation-pressure-limited accretion and mergers of stellar-mass seed BHs, left behind by the first generation of metal-free stars, or may be formed by more rapid direct collapse of gas in rare special environments where dense gas can accumulate without first fragmenting into stars. This chapter offers a review of these two competing scenarios, as well as some more exotic alternative ideas. It also briefly discusses how the different models may be distinguished in the future by observations with JWST, (e)LISA and other instruments.Comment: 47 pages with 306 references; this review is a chapter in "The First Galaxies - Theoretical Predictions and Observational Clues", Springer Astrophysics and Space Science Library, Eds. T. Wiklind, V. Bromm & B. Mobasher, in pres

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

A diverse suite of effector immune responses provide protection against various pathogens. However, the array of effector responses must be immunologically regulated to limit pathogen- and immune-associated damage. CD4+Foxp3+ regulatory T cells (Treg) calibrate immune responses; however, how Treg cells adapt to control different effector responses is unclear. To investigate the molecular mechanism of Treg diversity we used whole genome expression profiling and next generation small RNA sequencing of Treg cells isolated from type-1 or type-2 inflamed tissue following Leishmania major or Schistosoma mansoni infection, respectively. In-silico analyses identified two miRNA “regulatory hubs” miR-10a and miR-182 as critical miRNAs in Th1- or Th2-associated Treg cells, respectively. Functionally and mechanistically, in-vitro and in-vivo systems identified that an IL-12/IFNγ axis regulated miR-10a and its putative transcription factor, Creb. Importantly, reduced miR-10a in Th1-associated Treg cells was critical for Treg function and controlled a suite of genes preventing IFNγ production. In contrast, IL-4 regulated miR-182 and cMaf in Th2-associed Treg cells, which mitigated IL-2 secretion, in part through repression of IL2-promoting genes. Together, this study indicates that CD4+Foxp3+ cells can be shaped by local environmental factors, which orchestrate distinct miRNA pathways preserving Treg stability and suppressor function

Dark Matter in Low Surface Brightness Galaxies

Low Surface Brightness (LSB) galaxies form a large population of disc galaxies that extend the Hubble sequence towards extreme late-types. They are only slowly evolving, and still in an early evolutionary state. The Tully-Fisher relation and rotation curves of LSB galaxies both show that LSB galaxies are very dark-matter dominated with respect to ``normal'' high surface brightness (HSB) galaxies. Mass models derived from the rotation curves of LSB and HSB galaxies show that LSB galaxies inhabit less dense and more extended halos. Mass density, which changes with surface brightness, is as important in determining the evolution of a galaxy as total mass is.Comment: 8 pages, uses paspconf.sty. To be published in ``Dark and Visible Matter in Galaxies and Cosmological Implications'', Sesto Pusteria, Italy, 2-5 July, 1996,PASP Conference Series, eds M.Persic and P.Salucci. Also available at http://www.astro.rug.nl/~blok/lsb.htm