Pagets disease of uncertain origin: case report

BACKGROUND: Pagets disease of the nipple presents as an eczematous lesion, occurs in 1 – 4% of all female breast carcinoma cases and is invariably associated with underlying malignancy either overt or occult. The majority of these cases are invasive disease although 40–45% are associated with DCIS. CASE PRESENTATION: A 39 year old lady presented to our unit with a palpable lump in the right breast. Radiological and histological investigation proved this to be an extensive area of Ductal Carcinoma in Situ (DCIS) for which she underwent a simple mastectomy and immediate latissimus dorsi flap reconstruction. Histology revealed high grade DCIS with 2 small foci of invasive carcinoma. At 1 year the patient represented with a nodule adjacent to the reconstruction scar which was proved on biopsy to be consistent with Paget's disease. This was proved on formal excision. CONCLUSION: In the absence of underlying breast or apocrine tissue this case details a case of Paget's disease of uncertain origin

Parent perceptions and decision making about treatments for epilepsy : a qualitative evidence synthesis

Peer reviewedPublisher PD

Star Formation and AGN Activity in Galaxy Clusters from z=1−2z=1-2: a Multi-wavelength Analysis Featuring HerschelHerschel/PACS

We present a detailed, multi-wavelength study of star formation (SF) and AGN activity in 11 near-infrared (IR) selected, spectroscopically confirmed, massive ($\gtrsim10^{14}\,\rm{M_{\odot}}$) galaxy clusters at $1<z<1.75$. Using new, deep $Herschel$/PACS imaging, we characterize the optical to far-IR spectral energy distributions (SEDs) for IR-luminous cluster galaxies, finding that they can, on average, be well described by field galaxy templates. Identification and decomposition of AGN through SED fittings allows us to include the contribution to cluster SF from AGN host galaxies. We quantify the star-forming fraction, dust-obscured SF rates (SFRs), and specific-SFRs for cluster galaxies as a function of cluster-centric radius and redshift. In good agreement with previous studies, we find that SF in cluster galaxies at $z\gtrsim1.4$ is largely consistent with field galaxies at similar epochs, indicating an era before significant quenching in the cluster cores ($r<0.5\,$Mpc). This is followed by a transition to lower SF activity as environmental quenching dominates by $z\sim1$. Enhanced SFRs are found in lower mass ($10.1< \log \rm{M_{\star}}/\rm{M_{\odot}}<10.8$) cluster galaxies. We find significant variation in SF from cluster-to-cluster within our uniformly selected sample, indicating that caution should be taken when evaluating individual clusters. We examine AGN in clusters from $z=0.5-2$, finding an excess AGN fraction at $z\gtrsim1$, suggesting environmental triggering of AGN during this epoch. We argue that our results $-$ a transition from field-like to quenched SF, enhanced SF in lower mass galaxies in the cluster cores, and excess AGN $-$ are consistent with a co-evolution between SF and AGN in clusters and an increased merger rate in massive haloes at high redshift.Comment: 26 pages, 14 figures, 6 tables with appendix, accepted for publication in the Astrophysical Journa

Co-producing composite storytelling comics : (counter) narratives by academics of working-class heritage

This work was supported by the Society for Research into Higher Education, (grant number Davis NR2129).Composite storytelling as a social qualitative research method represents a growing spirit of creativity to explore themes of social injustice. This article discusses the potential methodological affordances and challenges of such approaches when used to collectively unsettle, interrogate and (re)imagine what it means to become an academic of working-class heritage. The participatory project discussed in this paper involved eight social science and humanities academics in UK-based elite higher education institutions. In a series of storytelling sessions, the participants created narrative encounters to foster moments of critique and analysis to explore the complex social realities of their routes into and through academia as people of working-class origins. Working alongside an illustrator, the participants used empirical insights to create composite stories in multimodal comic formats. Through this work, we seek to prompt further discussions about the generative possibilities of pursuing similar methods in the social sciences and beyond to challenge forms of social injustice.Peer reviewe

‘Ladies present!’: an auto/ethnographic study of women amateur golfers at an English provincial golf club

Despite high general participation rates in golf in England and a raft of initiatives to encourage more women and younger players into golf, fewer than one in five amateur golfers in England is female and there is a real dearth of young women entering the sport. Sexist policies and practices have been posited as possible barriers to women’s and girls’ grass-roots participation in golf, but to date little qualitative research has been undertaken on the lived experiences of recreational women players themselves. To address this considerable gap, an 18-month ethnographic and autoethnographic research project was undertaken within a case study club in the English East Midlands. Drawing on data from in-depth interviews with thirteen amateur women-players, ethnographic observations, detailed autoethnographic field notes and video auto-reflections, this article explores some of the key themes that emerged from the research, utilising primarily Foucauldian-feminist theoretical perspectives to frame the qualitative findings. The two key themes selected for analysis here are: 1) women’s lived experience of corporeal surveillance in golfing contexts; and: 2) discursive othering and objectification of women in golf. Keywords: women’s golf; ethnography; autoethnography; Foucault; surveillanc