Acute Liver Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference

CONTEXT Develop evidence-based criteria for individual organ dysfunction. OBJECTIVES Evaluate current evidence and develop contemporary consensus criteria for acute liver dysfunction with associated outcomes in critically ill children. DATA SOURCES Electronic searches of PubMed and Embase conducted from January 1992 to January 2020, used medical subject heading terms and text words to characterize acute liver dysfunction and outcomes. STUDY SELECTION Studies evaluating critically ill children with acute liver dysfunction, assessed screening tools, and outcomes were included. Studies evaluating adults, infants ≤36 weeks gestational age, or animals or were reviews/commentaries, case series with sample size ≤10, or non-English language studies were excluded. DATA EXTRACTION Data were abstracted from each eligible study into a data extraction form along with risk of bias assessment by a task force member. RESULTS The systematic review supports criteria for acute liver dysfunction, in the absence of known chronic liver disease, as having onset of symptoms <8 weeks, combined with biochemical evidence of acute liver injury, and liver-based coagulopathy, with hepatic encephalopathy required for an international normalized ratio between 1.5 and 2.0. LIMITATIONS Unable to assess acute-on-chronic liver dysfunction, subjective nature of hepatic encephalopathy, relevant articles missed by reviewers. CONCLUSIONS Proposed criteria identify an infant, child, or adolescent who has reached a clinical threshold where any of the 3 outcomes (alive with native liver, death, or liver transplant) are possible and should prompt an urgent liaison with a recognized pediatric liver transplant center if liver failure is the principal driver of multiple organ dysfunction

Property Rights in a Fishery: Regulatory Change and Firm Performance

A new method is introduced and applied to analyse changes in productivity of firms harvesting a natural capital stock. The index-number technique decomposes the contributions of output prices, variable input prices, fixed inputs and productivity to firm profits, adjusted for changes in the natural capital stock. An application of the method is given using micro-level data from a common-pool resource. The indexes provide a ready-made comparison of all firms to the most profitable firm per unit of resource stock. Benchmarking with the decompositions also allows firms and regulators to determine what components are contributing most to economic profits and improve overall industry performance.productivity,profits,natural capital,index numbers

Capacity And Capacity Utilization In Fishing Industries

The definition and measurement of capacity in fishing and other natural resource industries possess unique problems because of the stock-flow production technology, in which inputs are applied to the natural resource stock to produce a flow of output. In addition, there are often multiple resource stocks, corresponding to different species, with a mobile stock of capital that can exploit one or more of these stocks. In turn, this leads to three unique issues: (1) multiple stocks of capital and the resource; (2) that of aggregation or how to define the industry and resource stocks to consider; and (3), that of latent capacity or how to include stocks of capital that are currently inactive or exploit the resource stock only at low levels of variable input utilization. This paper presents appropriate definitions of capacity and methods for measuring capacity in fishing industries taking into consideration these issues.https://scholarworks.wm.edu/vimsbooks/1060/thumbnail.jp

Deterministic and Stochastic Capacity Estimation for Fishery Capacity Reduction

Deterministic data envelopment analysis (DEA) and stochastic pro- duction frontier (SPF) models are alternative methods for estimating capacity in fisheries. Fishery managers should be aware of likely differences in the capacity estimates obtained from these approaches if such estimates are to be used to support capacity reduction programs. In this paper, we provide a comparative analysis of DEA and SPF capacity estimates for a variety of possible capacity concepts using a panel data set for 10 vessels in the U.S. Northwest Atlantic scallop fishery. We find that DEA capacity output measures are higher than cor- responding SPF measures, but that the two approaches provide similar guidance about overall and even relative boat-specific capacity levels under certaincircumstances. The variations that emerge suggest, in particular, that biases can arise from inferring capacity output at efficient production levels, which dis- regards customary and usual operating conditions

Adjustable microchip ring trap for cold atoms and molecules

We describe the design and function of a circular magnetic waveguide produced from wires on a microchip for atom interferometry using deBroglie waves. The guide is a two-dimensional magnetic minimum for trapping weak-field seeking states of atoms or molecules with a magnetic dipole moment. The design consists of seven circular wires sharing a common radius. We describe the design, the time-dependent currents of the wires and show that it is possible to form a circular waveguide with adjustable height and gradient while minimizing perturbation resulting from leads or wire crossings. This maximal area geometry is suited for rotation sensing with atom interferometry via the Sagnac effect using either cold atoms, molecules and Bose-condensed systems

FISHING SKILL IN DEVELOPING COUNTRY FISHERIES: THE KEDAH, MALAYSIA TRAWL FISHERY

Fishing skill is perceived to play a crucial role in catching fish. The question arises for fishery managers as to whether or not there are observable and measurable attributes of the skipper or vessel that can be monitored and regulated to account for skipper skill and, hence, this source of fishing capacity. Equating technical efficiency with skipper skill, this paper evaluates technical efficiency and skipper skill in the Kedah, Malaysia, trawl fishery to address this issue.Resource /Energy Economics and Policy,

Whitehead's vision and the possibilities for the Christological adventure

The Intention of this thesis is to develop a Process christology which is valid and coherent with respect to the principles of Whitehead's Process philosophy and adequate with respect to Christian faith. As indicated by the title, the study moves from Whitehead's vision to the christological adventure. Although this necessitates that the criteria are essentially philosophical, it is stressed that the discussion finds its inspiration in faith. For that reason the second chapter describes the Process christologies of Norman Pittenger. John Cobb, Schubert Ogden and David Griffin. That discussion isolates the major questions and issues which arise. Chapter three is an examination of the philosophical principles of Whitehead's vision. A central thesis of the work is that the theory of "initial aims" is inadequate to account for the idea of a Divine purpose relevant to human beings. I illustrate why this is so and, after presenting a Process theory of the "self", describe how the notion of purpose mediated in history is Intelligible. Chapter four is a synthesis between the issues raised in the second chapter and the philosophical themes of chapter three. This chapter presents the christology which is valid with respect to Whitehead's vision. The following chapter observes that the Church is an essential aspect of Process christology, and then evaluates Christ and the Church with respect to some of' the themes of Biblical and traditional christology. The intention is to justify its status as an appropriate expression of faith, although it is accepted that the essential subjectivity of faith renders an objective evaluation impossible. The final chapter offers some concluding remarks, noting particularly how Process christology is a theology of liberation : freedom and responsibility