Making Space : creative learners, digital spaces, and the relationships between them

This thesis is an inquiry into the growing prevalence of digital learning environments or digital spaces in order to assess the impact of leveraging these spaces on learners\u27 creative identities. What is being examined in particular are web-folios or personal websites (digital spaces), the interactions that learners have with these environments, and how it infers to the potential of digital space as a medium for a variety of advancements. Through qualitative analysis in the form of observations, interviews, and surveys done throughout a collaborative research workshop, this thesis speculates that digital space can be utilized as a means for providing significant opportunities for individual growth and fostering creative identity. This research also acknowledges the reality of resource disparities within technology and possible means for improvement

Síndrome dos ovários policísticos : revisando o diagnóstico e o manejo dos distúrbios metabólicos

Polycystic ovary syndrome (PCOS) is a common condition in women at reproductive age associated with reproductive and metabolic dysfunction. Proposed diagnosed criteria for PCOS include two out of three features: androgen excess, menstrual irregularity, and polycystic ovary appearance on ultrasound (PCO), after other causes of hyperandrogenism and dysovulation are excluded. Based on these diagnostic criteria, the most common phenotypes are the “classic PCOS” – hyperandrogenism and oligomenorrhea, with or without PCO; the “ovulatory phenotype” – hyperandrogenism and PCO in ovulatory women; and the “non-hyperandrogenic phenotype”, in which there is oligomenorrhea and PCO, without overt hyperandrogenism. The presence of obesity may exacerbate the metabolic and reproductive disorders associated with the syndrome. In addition, PCOS women present higher risk for type 2 diabetes and higher prevalence of cardiovascular risk factors that seems to be associated with the classic phenotype. The main interventions to minimize cardiovascular and metabolic risks in PCOS are lifestyle changes, pharmacological therapy, and bariatric surgery. Treatment with metformin has been shown to improve insulin sensitivity, lowering blood glucose and androgen levels. These effects are more potent when combined with lifestyle interventions. In conclusion, besides reproductive abnormalities, PCOS has been associated to metabolic comorbidities, most of them linked to obesity. Confounders, such as the lack of standard diagnostic criteria, heterogeneity of the clinical presentation, and presence of obesity, make management of PCOS difficult. Therefore, the approach to metabolic abnormalities should be tailored to the risks and treatment goals of each individual woman.A síndrome dos ovários policísticos (PCOS) é um distúrbio frequente em mulheres em idade reprodutiva, associado com disfunção reprodutiva e metabólica. Os critérios diagnósticos atuais para PCOS incluem pelo menos dois dos três seguintes: hiperandrogenismo, irregularidade menstrual e aparência policística dos ovários à ultrassonografia (PCO), após exclusão de outras causas de hiperandrogenismo e anovulação. Com base nesses critérios diagnósticos, os fenótipos mais comuns são “PCOS clássico”– hiperandrogenismo e oligomenorreia, com ou sem PCO; o “fenótipo ovulatório” – hiperandrogenismo e PCO em mulheres ovulatórias; e o “fenótipo não hiperandrogênico”– no qual ocorrem oligomenorreia e PCO sem hiperandrogenismo evidente. A presença de obesidade pode exacerbar os distúrbios metabólicos e reprodutivos associados com a síndrome. Além disso, mulheres com PCOS apresentam maior risco para diabetes tipo 2 e maior prevalência de fatores de risco cardiovascular, que parecem estar associados com o fenótipo clássico. As principais intervenções para minimizar riscos metabólicos e cardiovasculares em PCOS são mudanças de estilo de vida, tratamento farmacológico e cirurgia bariátrica. O tratamento com metformina melhora a sensibilidade à insulina, reduz a glicemia e os níveis de androgênios. Esses efeitos são mais evidentes quando a metformina é associada às mudanças de estilo de vida. Em conclusão, além das anormalidades reprodutivas, a PCOS tem sido associada com comorbidades metabólicas ligadas à obesidade. Fatores confundidores, como a falta de critérios diagnósticos padronizados, heterogeneidade da apresentação clínica e presença de obesidade, tornam difícil o manejo clínico de PCOS. Assim, a abordagem das anormalidades metabólicas deve ser individualizada para os riscos e objetivos terapêuticos de cada mulher

Comparison of path-planning and search methods for cooperating unmanned aerial vehicles

The main goal of this research effort is develop a simulation environment for cooperating UAVs within MATLAB\u27s SIMULINK. This is the first step in a process that will eventually lead to the implementation of model UAVs on a model battlefield. The interest in cooperation of UAVs over the past decade has grown significantly. This is due to several reasons including lower operational cost, lower risk for humans, and greater maneuverability.;This research explores two scenarios. The first is a scenario in which all of the characteristics of a battlefield are known prior to the UAVs being launched. Three prevalent path-planning methods are compared based on calculation speed and optimization. This thesis shows that a visibility graph method leads to the lowest cost solution, while the Voronoi diagram method provides a computationally inexpensive solution.;The second scenario is a search and destroy mission where nothing is known about the battlefield prior to UAVs launch. This will consist of the vehicles visiting a set of predetermined waypoints until a target is found. The result of this research produces a simulation of cooperating UAVs that shows the potential of fulfilling many realistic missions in a battlefield environment