An investigation into the feasibility of myoglobin-based single-electron transistors

Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference. The results suggest single electron transport is mediated by resonant tunneling with the electronic and vibrational levels of the heme group in a single protein. They also represent a proof-of-principle that proteins with redox centers across nanometer-gap electrodes can be utilized to fabricate single-electron transistors. The protein orientation and conformation may significantly affect the conductance of these devices. Future improvements in device reproducibility and yield will require control of these factors

First Scientific Results From The Infrared Astronomical Satellite (IRAS)

The Infrared Astronomical Satellite (IRAS) was successfully launched on 25 January 1983 and terminated science data acquisition on 22 November 1983. The in-orbit performance of the telescope has been described in two previous papers in these proceedings. A previous description of very preliminary scientific results from the mission has been given in these proceedings, while far more extensive reports have been given elsewhere. In this paper we will summarize some of the results obtained to date from the IRAS data. The work to date has sampled only a small fraction of the IRAS data; the study of the data from the IRAS survey will continue for many years to come

On Spacetimes with Constant Scalar Invariants

We study Lorentzian spacetimes for which all scalar invariants constructed from the Riemann tensor and its covariant derivatives are constant ($CSI$ spacetimes). We obtain a number of general results in arbitrary dimensions. We study and construct warped product $CSI$ spacetimes and higher-dimensional Kundt $CSI$ spacetimes. We show how these spacetimes can be constructed from locally homogeneous spaces and $VSI$ spacetimes. The results suggest a number of conjectures. In particular, it is plausible that for $CSI$ spacetimes that are not locally homogeneous the Weyl type is $II$, $III$, $N$ or $O$, with any boost weight zero components being constant. We then consider the four-dimensional $CSI$ spacetimes in more detail. We show that there are severe constraints on these spacetimes, and we argue that it is plausible that they are either locally homogeneous or that the spacetime necessarily belongs to the Kundt class of $CSI$ spacetimes, all of which are constructed. The four-dimensional results lend support to the conjectures in higher dimensions.Comment: 25 pages, 1 figure, v2: minor changes throughou

Fabrication of an Active Electronic Device Using a Hetero-bimetallic Coordination Polymer

A nickel(II)/lead(II) coordination polymer [(NCS)Pb(H2O)LNi(NCS)]n {H2L=N,N′-bis(3-methoxysalicylidene)propane-1,3-diamine} has been synthesized and characterized. The band gap (3.18 eV) calculated from Tauc’s plot suggests the semiconducting nature of the complex. The material has a photosensitivity of 5.76, indicating its applicability in the fabrication of photosensitive devices. The complex has been successfully applied in a technologically challenging thin-film photosensitive Schottky device

A kapwa-infused paradigm in teaching Catholic theology/catechesis in a multireligious classroom in the Philippines

The increasing religious diversity in educational space has raised a legitimate question on how Catholic theology/ catechesis must be taught in Philippine Catholic universities given the institutional mandate to educate students “into the faith of the Church through teaching of Christian doctrine in an organic and systematic way” (Wuerl, 2013, 1). On this note, the paper makes reference to “centered plural- ism” (CP), a positional posture espoused by Georgetown University in dealing with this predicament. In an attempt to (re) appropriate CP into local context, there is a need to explore the Filipino conception of self/others as enveloped within the indigenous concept of kapwa. Hereon, the paper finds that CP is not just feasibly suitable in local context but with kapwa's more inclusive description of the relationship of self and others, a CP‐based teaching paradigm in theology/ catechesis is a promising project in the educational scene of the Philippines

Mathematical description of bacterial traveling pulses

The Keller-Segel system has been widely proposed as a model for bacterial waves driven by chemotactic processes. Current experiments on {\em E. coli} have shown precise structure of traveling pulses. We present here an alternative mathematical description of traveling pulses at a macroscopic scale. This modeling task is complemented with numerical simulations in accordance with the experimental observations. Our model is derived from an accurate kinetic description of the mesoscopic run-and-tumble process performed by bacteria. This model can account for recent experimental observations with {\em E. coli}. Qualitative agreements include the asymmetry of the pulse and transition in the collective behaviour (clustered motion versus dispersion). In addition we can capture quantitatively the main characteristics of the pulse such as the speed and the relative size of tails. This work opens several experimental and theoretical perspectives. Coefficients at the macroscopic level are derived from considerations at the cellular scale. For instance the stiffness of the signal integration process turns out to have a strong effect on collective motion. Furthermore the bottom-up scaling allows to perform preliminary mathematical analysis and write efficient numerical schemes. This model is intended as a predictive tool for the investigation of bacterial collective motion

How many sigmas is the solar neutrino effect?

The minimal standard electroweak model can be tested by allowing all the solar neutrino fluxes, with undistorted energy spectra, to be free parameters in fitting the measured solar neutrino event rates, subject only to the condition that the total observed luminosity of the sun is produced by nuclear fusion. The rates of the five experiments prior to SNO (chlorine, Kamiokande, SAGE, GALLEX, Super-Kamiokande) cannot be fit by an arbitrary choice of undistorted neutrino fluxes at the level of 2.5 sigma (formally 99% C.L.). Considering just SNO and Super-Kamiokande, the discrepancy is at the 3.3 sigma level(10^{-3} C.L.). If all six experiments are fit simultaneously, the formal discrepancy increases to 4 sigma (7*10^{-5} C.L.). If the relative scaling in temperature of the nuclear reactions that produce 7Be and 8B neutrinos is taken into account, the formal discrepancy is at the 7.4 sigma level.Comment: 1 figure; related information at http://www.sns.ias.edu/~jn

Can three-flavor oscillations solve the solar neutrino problem?

The most promising solution to the solar neutrino problem are neutrino oscillations, which usually are analyzed within the reduced 2-flavor scheme, because the solutions found therein reasonably well reproduce the recent data of Super-Kamiokande about the recoil-electron energy spectrum, zenith-angle and seasonal variations, and the event rate data of all the neutrino detectors. In this work, however, a survey of the complete parameter space of 3-flavor oscillations is performed. Basically eight new additional solutions could be identified, where the best one with \Delta m(12)^2=2.7x10^(-10) eV^2, \Delta m(13)^2=1.0x10^(-5) eV^2, \Theta(12)=23, and \Theta(13)=1.3 (denoted SVO) is slightly more probable than any 2-flavor solution. However, including the results of the atmospheric neutrino problem excludes all 3-flavour solutions apart from the SLMA-solution (\Delta m(12)^2=7.9x10^(-6) eV^2, \Delta m(13)^2=2.5x10^(-4) eV^2, \Theta(12)=1.4, and \Theta(13)=20). Besides, the ability of SNO and Borexino to discriminate the various 2- and 3-flavor solutions is investigated. Only with very good statistics in these experiments the correct solution to the solar neutrino problem can be identified unambiguously.Comment: 22 pages, 19 figures, REVTeX, submitted to Phys.Rev.D, article with better resolved figures available under http://www.mpa-garching.mpg.de/~schlattl/public.htm

The luminosity constraint on solar neutrino fluxes

A specific linear combination of the total solar neutrino fluxes must equal the measured solar photon luminosity if nuclear fusion reactions among light elements are responsible for solar energy generation. This luminosity constraint, previously used in a limited form in testing the no neutrino oscillation hypothesis, is derived in a generality that includes all of the relevant solar neutrino fluxes and which is suitable for analyzing the results of many different solar neutrino experiments. With or without allowing for neutrino oscillations, the generalized luminosity constraint can be used in future analyses of solar neutrino data. Accurate numerical values for the linear coefficients are provided.Comment: related material at http://www.sns.ias.edu/~jn

Overview of mathematical approaches used to model bacterial chemotaxis I: the single cell

Mathematical modeling of bacterial chemotaxis systems has been influential and insightful in helping to understand experimental observations. We provide here a comprehensive overview of the range of mathematical approaches used for modeling, within a single bacterium, chemotactic processes caused by changes to external gradients in its environment. Specific areas of the bacterial system which have been studied and modeled are discussed in detail, including the modeling of adaptation in response to attractant gradients, the intracellular phosphorylation cascade, membrane receptor clustering, and spatial modeling of intracellular protein signal transduction. The importance of producing robust models that address adaptation, gain, and sensitivity are also discussed. This review highlights that while mathematical modeling has aided in understanding bacterial chemotaxis on the individual cell scale and guiding experimental design, no single model succeeds in robustly describing all of the basic elements of the cell. We conclude by discussing the importance of this and the future of modeling in this area