Components Qualification for a Possible use in the Mu2e Calorimeter Waveform Digitizers

The Mu2e experiment at Fermilab searches for the charged flavor violating conversion of a muon into an electron in the Coulomb field of a nucleus. The detector consists of a straw tube tracker and a CSI crystal electromagnetic calorimeter, both housed in a superconducting solenoid. Both the front-end and the digital electronics, located inside the cryostat, will be operated in vacuum under a 1 T magnetic field, having to sustain the high flux of neutrons and ionizing particles coming from the muons stopping target. These harsh experimental conditions make the design of the calorimeter waveform digitizer quite challenging. All the selected commercial devices must be tested individually and qualified for radiation hardness and operation in high magnetic field. At the moment the expected particles flux and spectra at the digitizers location are not completely simulated and we are using initial rough estimates to select the components for the first prototype. We are gaining experience in the qualification procedures using the selected components but the choice will be frozen only when dose and neutron flux simulations will be completed. The experimental results of the first qualification campaign are presented.Comment: TWEPP 2016 - Topical Workshop on Electronics for Particle Physics, 26-30 September 2016, Karlsruhe Institute of Technology (KIT

Thermal evolution of hybrid stars within the framework of a nonlocal Nambu--Jona-Lasinio model

We study the thermal evolution of neutron stars containing deconfined quark matter in their core. Such objects are generally referred to as quark-hybrid stars. The confined hadronic matter in their core is described in the framework of non-linear relativistic nuclear field theory. For the quark phase we use a non-local extension of the SU(3) Nambu Jona-Lasinio model with vector interactions. The Gibbs condition is used to model phase equilibrium between confined hadronic matter and deconfined quark matter. Our study indicates that high-mass neutron stars may contain between 35 and 40 % deconfined quark-hybrid matter in their cores. Neutron stars with canonical masses of around $1.4\, M_\odot$ would not contain deconfined quark matter. The central proton fractions of the stars are found to be high, enabling them to cool rapidly. Very good agreement with the temperature evolution established for the neutron star in Cassiopeia A (Cas A) is obtained for one of our models (based on the popular NL3 nuclear parametrization), if the protons in the core of our stellar models are strongly paired, the repulsion among the quarks is mildly repulsive, and the mass of Cas A has a canonical value of $1.4\, M_\odot$.Comment: 10 pages, 7 figure

Overview of the Current Literature on the Most Common Neurological Diseases in Dogs with a Particular Focus on Rehabilitation

Simple Summary This paper aims to report an overview of the most common neurological diseases (intervertebral disc herniation, degenerative myelopathy, fibrocartilaginous embolism, and polyradiculoneuritis), with a main focus on rehabilitative options and outcomes, reported in recent veterinary literature. Literature seems to be positively oriented on the efficacy of the rehabilitation approach, reporting a careful and prudent choice of the protocol to be applied for the correct recovery of the patient. However, blinded, controlled, prospective studies are still necessary, above all for degenerative myelopathy, fibrocartilaginous embolism, and polyradiculoneuritis. Intervertebral disc herniation, degenerative myelopathy, fibrocartilaginous embolism and polyradiculoneuritis often affect dogs; and physiotherapy may improve the patient's quality of life and/or reduce recovery times. The aim of this review was to evaluate the current scientific outcomes on these four neurological diseases and on their physiotherapy approaches. From the analysis of the published articles, it emerged that intervertebral disc herniation can be treated, with different rates of success, through a conservative or a surgical approach followed by physiotherapy. The literature is generally oriented toward the efficacy of the rehabilitation approach in this specific canine disease, often proposing intensive post-surgery physiotherapy for the most severe conditions with the absence of deep pain perception. When degenerative myelopathy, fibrocartilaginous embolism or polyradiculoneuritis occur, the existing literature supports the use of a physiotherapeutic approach: allowing a delay in the onset and worsening of the clinical signs in degenerative myelopathy, physical improvement, and, sometimes, complete remission during fibrocartilaginous embolism or acute idiopathic polyradiculoneuritis. However, papers on rehabilitation in dogs affected by polyradiculoneuritis are currently limited to single clinical cases and further blinded, controlled, prospective studies are still advisable for all four neurological diseases

Observational study on lameness recovery in 10 dogs affected by iliopsoas injury and submitted to a physiotherapeutic approach

This preliminary study has investigated the outcome of physiotherapy in 10 dogs affected by a primary lesion of the iliopsoas muscle and the potential effects of sex, age, and breed on recovery. Ten dogs with primary injury of the iliopsoas muscle were retrospectively included in this study. Dogs were submitted to a rehabilitation program, characterized by a multimodal approach, including physical therapies and modalities. After recovery, patients were submitted to a further support period of rehabilitation to promote muscle strengthening and limit injury recurrence during their return to normal functional and sports activity. Border collies were highly represented. The recovery of lameness occurred after a mean of 22.6 ± 14.7 (median 18) days with a median number of five sessions. None of the examined variables affected the recovery time, except for the border collie breed, which showed a significantly faster recovery time; however, there was no difference between the breeds with regard to the number of sessions. Multimodal rehabilitation therapy may promote lameness recovery of mild-to-moderate iliopsoas lesions within 3 weeks. This preliminary study reports a clinical approach and recovery of primary iliopsoas lesions, findings that can provide clinicians with useful prognostic information for dogs involved in sports activities

Surgical repair of Achilles tendon rupture in dogs: A review of the literature, a case report and new perspectives

Achilles tendon rupture in the dog is a common traumatic lesion. An accurate evaluation of etiology, grade of the lesion with or without loss of tendon substance, and time elapsed from the trauma can guide the surgeon in choosing the best surgical technique. Moreover, the healing process after a tendon injury is usually difficult and uncertain because the prognosis is influenced by extent of trauma, time elapsed between the trauma and its treatment and low tendon vascularization. However, the rapid development of tissue engineering and regenerative medicine could soon result in the development of scaffolds with bioactive proteins that can direct the healing process toward complete tendon regeneration without fibrotic tissue development

Macro-micro relationship in nanostructured functional composites

This paper examines the results of the characterization of two functional composites: Poly(methyl methacrylate) (PMMA)-Ce:YAG (yttrium aluminium garnet doped with cerium) and PMMA-cobalt hexacyanoferrate (CoHCF). The composites were prepared as possible emitters in the fields of lighting thermal sensors. The prepared composites were characterized using transmission electron microscopy (TEM), nuclear magnetic resonance (NMR) spectroscopy, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) analyses to study the correlation between micro and macro characteristics. We found that the molecular interactions of the two different fillers with the matrix were localized in different sites of the polymer chains. Moreover, the composites showed an increased thermal strength and stiffness, in particular the PMMA-Ce:YAG composite

Clinical evaluation of creatine kinase and aspartate aminotransferase for monitoring muscle effort in working dogs in different simulated fieldworks

The clinical profiles of muscle biomarkers (Creatine Kinase–CK-and Aspartate Aminotransferase–AST) performed during training may help in determining the fitness level of dogs and their potentiality to perform specific activities. This study investigated the potential variations of physiological parameters and muscular biomarkers in trained search and rescue dogs during search activity in two different areas. The aim was to verify the absence of any muscular enzymes after 20 min of search activity. The variations of physiological parameters (pulse rate; respiratory rate; rectal body temperature) and skeletal muscular biomarkers (CK and AST) were evaluated before and after search activity. Twenty-three trained dogs met the inclusion criteria and were divided into two groups. One group experienced search activity in a well-known area, while the second one in a similar, but unknown, area. The results for physiological parameters and skeletal muscular biomarkers values showed no significant differences between the two groups (p > 0.05), confirming that an effective conditioning protects against enzymatic alteration during a 20 min duration of submaximal activity

Effects of exercise on urinary biochemical parameters and proteins in a group of well-trained military working dogs

Exercise-induced proteinuria has been widely investigated in humans, also in relation to intensity and duration of activity. Instead, there are only limited publications regarding urinary biochemical parameters and urinary proteins before and after physical activity in dogs. This paper aimed to investigate the effects of exercise on urinary biochemistry and proteins in military dogs. Twenty-four dogs were enrolled in this study. All the dogs were clinically sound, and they were examined before and after activity. Pulse rates (PR) and respiratory rate (RR) were monitored. Urine was sampled before and after a training session of search activity. Standard urinalysis was carried out, urine total proteins and creatinine were measured and the urinary protein:creatinine ratio was calculated; finally, the urinary proteins were separated using sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). Clinical examination before and after activity did not reveal any pathological finding. After activity, the PR was slightly increased, while the RR was notably increased (p < 0.05). Total proteins, albumin, and their ratio with creatinine were significantly higher after exercise when considering all the dogs included or only the females while, when considering only the males no significant difference was detected. The clinical relevance of this study was related to the possibility of using urine as a non-invasive sample for monitoring health status after training activity and exercise in dogs. An increase in microalbuminuria after search activity, measured using SDS-PAGE could be considered an early biomarker of renal function during training sessions

Frontal Polymerization and Geopolymerization, the First Example: Organic-Inorganic Hybrid Materials

This work shows the first example of frontal geopolymerization, obtained in the same reactor in which the frontal polymerization of 1,6 hexanediolodiaacrylate occurs at the same time; the simultaneous frontal polymerization allows to obtain an organic-inorganic hybrid material in a single step and in a short time (a few minutes), thanks to the exothermicity of the two reactions which are mutually self-supporting. This technique represents the only way to obtain hybrid organic polymer-geopolymer mate-rials: using the classical polymerization (prolonged heating) the reaction is explosive due to the formation of gaseous products, while the polymerization at room temperature, due to the very long times, leads to a phase separation