2,185 research outputs found
An Overview of the Northern Gulf of Mexico Ecosystem
The Gulf of Mexico is a large marine ecosystem (LME) bordered by the southern United States, Mexico, and Cuba. This general overview of its northern portion covers physiography, significant oceanographic features, the influence of major rivers and freshwater, biological productivity, and food web characteristics. It then describes the pelagic and benthic components of the major habitats: oceanic (continental slope and abyssal plain), continental shelf and bays, estuaries, and marshes, with descriptions of prominent processes and some dominant organisms. For each habitat several species from a variety of trophic levels are introduced and their general role in the ecosystem discussed. In 2010 the northern portion of the Gulf was the site of the largest U.S. marine oil spill in history and is now the focus of an unprecedented restoration effort. Successful restoration of the northern Gulf will depend on an integrated view of this LME and the forces that maintain and change it. This introduction to the northern Gulf marine ecosystem should be useful for policy makers, informing decisions on proposed restoration actions
Biased chromatin signatures around polyadenylation sites and exons
Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between chromatin structure and pre-mRNA processing is poorly understood. We observed strong nucleosome depletion around human polyadenylation sites (PAS) and nucleosome enrichment just downstream of PAS. In genes with multiple alternative PAS, higher downstream nucleosome affinity was associated with higher PAS usage, independently of known PAS motifs that function at the RNA level. Conversely, exons were associated with distinct peaks in nucleosome density. Exons flanked by long introns or weak splice sites exhibited stronger nucleosome enrichment, and incorporation of nucleosome density data improved splicing simulation accuracy. Certain histone modifications, including H3K36me3 and H3K27me2, were specifically enriched on exons, suggesting active marking of exon locations at the chromatin level. Together, these findings provide evidence for extensive functional connections between chromatin structure and RNA processing
The analysis of spectra of novae taken near maximum
A project to analyze ultraviolet spectra of novae obtained at or near maximum optical light is presented. These spectra are characterized by a relatively cool continuum with superimposed permitted emission lines from ions such as Fe II, Mg II, and Si II. Spectra obtained late in the outburst show only emission lines from highly ionized species and in many cases these are forbidden lines. The ultraviolet data will be used with calculations of spherical, expanding, stellar atmospheres for novae to determine elemental abundances by spectral line synthesis. This method is extremely sensitive to the abundances and completely independent of the nebular analyses usually used to obtain novae abundances
Patterns of Tree Mortality During an Uncontrolled Spruce Budworm Outbreak in Baxter State Park, 1983
A forest inventory of Baxter State Park, Maine, was done during the summer and fall of 1983 to study the patterns of mortality in balsam fir and in the red-black spruce complex during an uncontrolled spruce budworm outbreak. The volume of trees that died during the outbreak was estimated at 40% of the original quantity. Fir mortality was consistently greater than that of spruce. The percentage mortality of spruce was always greater in the higher elevation zone than in the lower elevation zone. Percentage mortality of fir and spruce showed inconsistent patterns in relation to the proportion of hardwood species basal area and to the proportion of fir basal area in a stand. However, those mortality patterns tended to be pronounced when the overall tree mortality was relatively high. Hypotheses on the mechanisms producing the tree mortality patterns during a budworm outbreak were summarized and observed tree mortality patterns were then interpreted according to those hypotheses. Most observed patterns could be explained by more than one hypothesis. It was suggested that complex processes were responsible for developing certain tree mortality patterns, and a deductive method based on the simple observations would not reveal the true mechanisms.https://digitalcommons.library.umaine.edu/aes_techbulletin/1081/thumbnail.jp
Patterns of Tree Mortality During an Uncontrolled Spruce Budworm Outbreak in Baxter State Park, 1983
A forest inventory of Baxter State Park, Maine, was done during the summer and fall of 1983 to study the patterns of mortality in balsam fir and in the red-black spruce complex during an uncontrolled spruce budworm outbreak. The volume of trees that died during the outbreak was estimated at 40% of the original quantity. Fir mortality was consistently greater than that of spruce. The percentage mortality of spruce was always greater in the higher elevation zone than in the lower elevation zone. Percentage mortality of fir and spruce showed inconsistent patterns in relation to the proportion of hardwood species basal area and to the proportion of fir basal area in a stand. However, those mortality patterns tended to be pronounced when the overall tree mortality was relatively high. Hypotheses on the mechanisms producing the tree mortality patterns during a budworm outbreak were summarized and observed tree mortality patterns were then interpreted according to those hypotheses. Most observed patterns could be explained by more than one hypothesis. It was suggested that complex processes were responsible for developing certain tree mortality patterns, and a deductive method based on the simple observations would not reveal the true mechanisms.https://digitalcommons.library.umaine.edu/aes_techbulletin/1081/thumbnail.jp
Elastic Wavefield Modeling for Arbitrarily Oriented Orthotropic Media
Composite materials have gained a considerable importance, being widely applied e.g. in aerospace industries as unidirectional, layered or woven structures. Through their complex build-up these materials exhibit anisotropic elastic behavior, raising considerable difficulties for ultrasonic nondestructive testing techniques. In modeling the interaction of elastic waves with such media a simple tool of assisting analysis is available. In this respect, simulation and optimization allow for a reduction of experimental work and an increase in reliability of applied testing procedures. For materials exhibiting orthotropic elastic symmetry, fundamental plane wave characteristics are presented in this contribution. These relationships are further applied for transducer-field modeling using the Generalized Point Source Synthesis method [1]. Since for complex-shaped components the material’s natural symmetry planes are in general not identical with the component’s surfaces, a respective transformation has been applied recently to yield a compact elastic tensor representation for such configurations [2]. Based on this formulation, all analytical results are obtained in a coordinate-free form, where the material’s spatial orientation appears as an additional parameter. Since orthotropy includes the higher symmetries tetragonal, transversely isotropic, cubic and isotropic, the results presented cover most of the materials of today’s industrial interest. Numerical results cover slowness and group velocity diagrams as well as field pattern calculations for commercial transducers including time-depedent rf-impulse modeling
Vertical distribution of microbial and meiofaunal populations in sediments of a natural coastal hydrocarbon seep
We studied the vertical distribution of microbes and meiofauna in natural hydrocarbon seep sediments to determine if there was a relationship between profiles of benthic trophic structure and the unique biogeochemical conditions present at the seep. Three stations in the Santa Barbara Channel represented a gradient of natural petroleum seepage, from very active, to moderate, to none. Seasonal differences were examined by sampling in the three major oceanographic seasons, upwelling (April), mixed (July), and Davidson (December). Densities of microbes and meiofauna were highest in July, and decreased in winter. All population sizes decreased with increasing depth in the sediment. Harpacticoids and Chl a were practically restricted to the surface sediments. Harpacticoids and Chl a were more dense (number per unit volume or strata of sediment) and abundant (number per unit area of sediment or sum of the strata) at the comparison site than at the seep sites. Density and abundance of nematodes, bacteria cell counts, and bacterial biomass were greater at the station with the most active seepage rates. Bacterial biovolumes appeared constant among sediment depths and stations, but cell biovolumes were larger in July. The data are consistent with the hypothesis that organic enrichment via petroleum utilization is responsible for increased abundances of bacteria and nematodes at the seep. There were strong correlations between densities of harpacticoids and microalgae, and densities of nematodes and bacteria. These links indicate that seeping petroleum might have an enhanced effect on the detrital (bacterial based) food web, but a toxic effect on the grazing (microalgal based) food web
The responsiveness of the uterine fibroid symptom and health-related quality of life questionnaire (UFS-QOL)
Abstract Background A number of noninvasive alternatives to hysterectomy have become available as treatments for uterine fibroids. These alternative therapies, however, may not relieve all symptoms. Consequently, the need for patient-reported outcomes to assess symptom reduction of uterine fibroids has become increasingly important to evaluate the clinical success of patients who choose these alternative therapies. The purpose of the study was to examine the responsiveness of the Uterine Fibroid Symptom and Health-Related Quality of Life Questionnaire (UFS-QOL) with treatment of uterine fibroids. Methods The responsiveness of the UFS-QOL was assessed as a post-hoc analysis of patients treated with MRI-guided focused ultrasound thermal ablation (MRgFUS) for uterine fibroids. The UFS-QOL and SF-36 were completed at baseline and months 1, 3, and 6. Patient perceived overall treatment effect (OTE) was assessed at month 3, while satisfaction with treatment was collected at month 6. The responsiveness of the UFS-QOL was examined using effect sizes and change scores by patient-reported overall treatment effect and satisfaction. Results A total of 102 women with complete UFS-QOL data were included in the analysis; the mean age was 45 years and 79% were Caucasian. From baseline to 6 months, significant improvements were observed in UFS-QOL Symptom Severity and all Health-Related Quality of Life (HRQL) subscale scores (p Conclusion The UFS-QOL is responsive to treatment for uterine fibroids and is a useful outcome measure for uterine-sparing uterine fibroid treatments.</p
Temporal variability and the relationship between benthic meiofaunal and microbial populations of a natural coastal petroleum seep
Previous studies of the Isla Vista petroleum seep in the Santa Barbara Channel found much higher abundances of macrofauna and concentrations of adenosine triphosphate (ATP) in sediments near petroleum seepage compared to those from nonseep areas. To further assess the possible effect of petroleum on organisms at the base of benthic food webs, population abundances of meiobenthos and their suspected microbial food (bacteria and diatoms) were measured biweekly for one year at three stations with differing petroleum exposure. Determinations of suspended particulate matter and the abundance and gut contents of juvenile fishes were also made at seep and nonseep stations. Nematodes and bacteria had higher abundances in areas of active petroleum seepage than in areas of moderate seepage (within 20 m) or no seepage (1.4 km away). Bacterial productivity (based on the frequency of dividing cells) was 340% greater in sediments from areas of active seepage compared to those from a nonseep station. Sediments within the seep, but away from active seepage, had rates of bacterial productivity 15 times greater than a nonseep comparison site. Densities of harpacticoid copepods and their probable principal food, diatoms, were not affected by petroleum seepage. Suspended organic matter caught in settling traps was not different between seep and nonseep stations. In addition, there was no evidence that predation pressure by juvenile fish on meiofauna was different between stations. The higher bacterial biomass and productivity in areas of petroleum seepage are consistent with the hypothesis that petroleum carbon is available for assimilation by sediment bacteria. The enhanced level of microbial carbon associated with the petroleum seep is available for consumption by benthic invertebrates and could explain the higher abundances of macrofauna and meiofauna found there
Recognition of cognitive impairment and depressive symptoms in older patients with heart failure
INTRODUCTION: Cognitive impairment and depression in patients with heart failure (HF) are common comorbidities and are associated with increased morbidity, readmissions and mortality. Timely recognition of cognitive impairment and depression is important for providing optimal care. The aim of our study was to determine if these disorders were recognised by clinicians and, secondly, if they were associated with hospital admissions and mortality within 6 months’ follow-up. METHODS: Patients (aged ≥65 years) diagnosed with HF were included from the cardiology outpatient clinic of Gelre Hospitals. Cognitive status was evaluated with the Montreal Cognitive Assessment test (score ≤22). Depressive symptoms were assessed with the Geriatric Depression Scale (score >5). Patient characteristics were collected from electronic patient files. The clinician was blinded to the tests and asked to assess cognitive status and mood. RESULTS: We included 157 patients. Their median age was 79 years (65–92); 98 (62%) were male. The majority had New York Heart Association functional class II. Cognitive impairment was present in 56 (36%) patients. Depressive symptoms were present in 21 (13%) patients. In 27 of 56 patients (48%) cognitive impairment was not recognised by clinicians. Depressive symptoms were not recognised in 11 of 21 patients (52%). During 6 months’ follow-up 24 (15%) patients were readmitted for HF-related reasons and 18 (11%) patients died. There was no difference in readmission and mortality rate between patients with or without cognitive impairment and patients with or without depressive symptoms. CONCLUSION: Cognitive impairment and depressive symptoms were infrequently recognised during outpatient clinic visits
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