Seasonal MLT-region nightglow intensities, temperatures, and emission heights at a Southern Hemisphere midlatitude site

We consider 5 years of spectrometer measurements of OH(6–2) and O2(0–1) airglow emission intensities and temperatures made near Adelaide, Australia (35° S, 138° E), between September 2001 and August 2006 and compare them with measurements of the same parameters from at the same site using an airglow imager, with the intensities of the OH(8–3) and O(1S) emissions made with a filter photometer, and with 2 years of Aura MLS (Microwave Limb Sounder) v3.3 temperatures and 4.5 years of TIMED SABER (Thermosphere Ionosphere Mesosphere Energetics and Dynamics Sounding of the Atmosphere using Broadband Emission Radiometry) v2.0 temperatures for the same site. We also consider whether we can recover the actual emission heights from the intercomparison of the ground-based and satellite observations. We find a significant improvement in the correlation between the spectrometer OH and SABER temperatures by interpolating the latter to constant density surfaces determined using a meteor radar.Iain M. Reid, Andrew J. Spargo, Jonathan M. Woithe, Andrew R. Klekociuk, Joel P. Younger and Gulamabas G. Sivje

HRTEM study of orthorhombic zirconia in MgO-PSZ

High-resolution transmission electron microscopy (HRTEM) was used to study the phase of orthorhombic ZrO2 formed in magnesia partially stabilized zirconia (MgO-PSZ) during HRTEM specimen preparation. Based on the three reported crystal structures of orthorhombic ZrO2, with the space groups Pbcm, Pbc2(1) and Pbca, here it is shown that orthorhombic ZrO2 formed in MgO-PSZ has the Pbcm structure

Non-collinear magnetic structures: a possible cause for current induced switching

Current induced switching in Co/Cu/Co trilayers is described in terms of ab-initio determined magnetic twisting energies and corresponding sheet resistances. In viewing the twisting energy as an energy flux the characteristic time thereof is evaluated by means of the Landau-Lifshitz-Gilbert equation using ab-initio parameters. The obtained switching times are in very good agreement with available experimental data. In terms of the calculated currents, scalar quantities since a classical Ohm's law is applied, critical currents needed to switch magnetic configurations from parallel to antiparallel and vice versa can unambiguously be defined. It is found that the magnetoresistance viewed as a function of the current is essentially determined by the twisting energy as a function of the relative angle between the orientations of the magnetization in the magnetic slabs, which in turn can also explain in particular cases the fact that after having switched off the current the system remains in the switched magnetic configuration. For all ab-initio type calculations the fully relativistic Screened Korringa-Kohn-Rostoker method and the corresponding Kubo-Greenwood equation in the context of density functional theory are applied.Comment: 20 pages, 4 tables and 15 figures, submitted to PR

Momentum flux estimates accompanying multiscale gravity waves over Mount Cook, New Zealand, on 13 July 2014 during the DEEPWAVE campaign

Observations performed with a Rayleigh lidar and an Advanced Mesosphere Temperature Mapper aboard the National Science Foundation/National Center for Atmospheric Research Gulfstream V research aircraft on 13 July 2014 during the Deep Propagating Gravity Wave Experiment (DEEPWAVE) measurement program revealed a large-amplitude, multiscale gravity wave (GW) environment extending from ~20 to 90 km on flight tracks over Mount Cook, New Zealand. Data from four successive flight tracks are employed here to assess the characteristics and variability of the larger- and smaller-scale GWs, including their spatial scales, amplitudes, phase speeds, and momentum fluxes. On each flight, a large-scale mountain wave (MW) having a horizontal wavelength ~200-300 km was observed. Smaller-scale GWs over the island appeared to correlate within the warmer phase of this large-scale MW. This analysis reveals that momentum fluxes accompanying small-scale MWs and propagating GWs significantly exceed those of the large-scale MW and the mean values typical for these altitudes, with maxima for the various small-scale events in the range ~20-105 m2 s-2. Key Points Mountain waves penetrate the mesosphere under suitable propagation conditions Small-scale gravity waves can attain very large momentum fluxes Occurrence of peak momentum fluxes is often dictated by multiscale environments. © 2015. American Geophysical Union. All Rights Reserved

Increased activity of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in purified cell suspensions and single cells from the uterine cervix in cervical intraepithelial neoplasia.

The activities of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase have been measured in squamous epithelial cells of the uterine cervix from normal patients and cases of cervical intraepithelial neoplasia (CIN). A biochemical cycling method, which uses only simple equipment and is suited to routine use and to automation, was applied to cells separated by gradient centrifugation. In addition, cells were examined cytochemically, and the intensity of staining in the cytoplasm of single whole cells was measured using computerised microcytospectrophotometry. Twenty per cent of cells in samples from normal patients (n=61) showed staining intensities above an extinction of 0.15 at 540 nm, compared to 71% of cases of CIN 1 (n=14), 91% of cases of CIN 2 (n=11) and 67% of cases of CIN 3 (n=15). The cytochemical data do not allow definitive distinctions to be made between different grades of CIN whereas the biochemical assay applied to cell lysates shows convincing differences between normal samples and cases of CIN. There are no false negatives for CIN 3 (n=14) and CIN 2 (n=10) and 11% false negatives for CIN 1 (n=9) and 14% of false positives for normal cases (n=21). The results of this preliminary study with reference to automation are discussed [corrected]

Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review

Background Proteinuria is one of the essential criteria for the clinical diagnosis of pre-eclampsia. Increasing levels of proteinuria is considered to be associated with adverse maternal and fetal outcomes. We aim to determine the accuracy with which the amount of proteinuria predicts maternal and fetal complications in women with pre-eclampsia by systematic quantitative review of test accuracy studies. Methods We conducted electronic searches in MEDLINE (1951 to 2007), EMBASE (1980 to 2007), the Cochrane Library (2007) and the MEDION database to identify relevant articles and hand-search of selected specialist journals and reference lists of articles. There were no language restrictions for any of these searches. Two reviewers independently selected those articles in which the accuracy of proteinuria estimate was evaluated to predict maternal and fetal complications of pre-eclampsia. Data were extracted on study characteristics, quality and accuracy to construct 2 × 2 tables with maternal and fetal complications as reference standards. Results Sixteen primary articles with a total of 6749 women met the selection criteria with levels of proteinuria estimated by urine dipstick, 24-hour urine proteinuria or urine protein:creatinine ratio as a predictor of complications of pre-eclampsia. All 10 studies predicting maternal outcomes showed that proteinuria is a poor predictor of maternal complications in women with pre-eclampsia. Seventeen studies used laboratory analysis and eight studies bedside analysis to assess the accuracy of proteinuria in predicting fetal and neonatal complications. Summary likelihood ratios of positive and negative tests for the threshold level of 5 g/24 h were 2.0 (95% CI 1.5, 2.7) and 0.53 (95% CI 0.27, 1) for stillbirths, 1.5 (95% CI 0.94, 2.4) and 0.73 (95% CI 0.39, 1.4) for neonatal deaths and 1.5 (95% 1, 2) and 0.78 (95% 0.64, 0.95) for Neonatal Intensive Care Unit admission. Conclusion Measure of proteinuria is a poor predictor of either maternal or fetal complications in women with pre-eclampsia

Performance assessment of triple redundant nine-phase delta- and wye-connected permanent magnet-assisted synchronous reluctance motor under healthy and fault conditions

In this study, the performance of a triple redundant nine-phase permanent magnet-assisted synchronous reluctance motor with delta-connected windings is comprehensively assessed and compared with that of wye-connected winding under healthy and fault conditions, including open circuit, inter-turn short-circuit and terminal short circuit. The steady-state torque behaviour, loss, efficiency and temperature distribution of the two winding configurations are analysed and compared. It is shown that the delta-connected winding has higher output torque under one phase open-circuit fault and lower inter-turn short-circuit current with three-phase terminal short circuit

Performativity, border-crossings and ethics in a prison-based creative writing class

We critically reflect on insights from our experiences as female researchers on a creative writing project in a men’s prison, including the emotional impact on the men involved and the ways in which our role as participant researchers impacted deeply on us. Juxtaposed starkly with the physical constraints of the prison, a sense of journeys emerged as significant throughout the study, particularly the symbolic crossing of boundaries. We draw on theories of performativity from both Feminist and Symbolic Interactionist perspectives to frame our understanding of the experience of being participant researchers in prison creative writing workshops, and also consider associated ethical issues

Infliximab plus methotrexate is superior to methotrexate alone in the treatment of psoriatic arthritis in methotrexate-naive patients: the RESPOND study

Objective: To compare the efficacy and safety of treatment with infliximab plus methotrexate with methotrexate alone in methotrexate-naive patients with active psoriatic arthritis (PsA). Methods: In this open-label study, patients 18 years and older with active PsA who were naive to methotrexate and not receiving disease-modifying therapy (N=115) were randomly assigned (1:1) to receive either infliximab (5 mg/kg) at weeks 0, 2, 6 and 14 plus methotrexate (15 mg/week); or methotrexate (15 mg/week) alone. The primary assessment was American College of Rheumatology (ACR) 20 response at week 16. Secondary outcome measures included psoriasis area and severity index (PASI), disease activity score in 28 joints (DAS28) and dactylitis and enthesitis assessments. Results: At week 16, 86.3% of patients receiving infliximab plus methotrexate and 66.7% of those receiving methotrexate alone achieved an ACR20 response (p<0.02). Of patients whose baseline PASI was 2.5 or greater, 97.1% receiving infliximab plus methotrexate compared with 54.3% receiving methotrexate alone experienced a 75% or greater improvement in PASI (p<0.0001). Improvements in C-reactive protein levels, DAS28 response and remission rates, dactylitis, fatigue and morning stiffness duration were also significantly greater in the group receiving infliximab. In the infliximab plus methotrexate group, 46% (26/57) had treatment-related adverse events (AE) and two patients had serious AE, compared with 24% with AE (13/54) and no serious AE in the methotrexate-alone group. Conclusions: Treatment with infliximab plus methotrexate in methotrexate-naive patients with active PsA demonstrated significantly greater ACR20 response rates and PASI75 improvement compared with methotrexate alone and was generally well tolerated. This trial is registered in the US National Institutes of Health clinicaltrials.gov database, identifier NCT00367237