14 research outputs found
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Vestibular functions in patients with tinnitus only
Objective: Tinnitus is the perception of sound in the ears or head without any external or internal acoustic stimulation, and it is usually associated with hearing loss. In addition, it has been reported that there is a relationship between vestibular problems and sensorineural hearing loss. The aim of this study was to evaluate the vestibular function in patients with tinnitus without hearing loss.
Methods: A total of 32 patients who complained only of tinnitus without hearing loss and 30 control subjects without tinnitus or hearing loss were included in this study. Oculomotor and caloric tests were performed on all subjects with videonystagmography. The tinnitus handicap inventory questionnaire, side and duration of tinnitus were recorded in all patients.
Results: The caloric test was abnormal in 13 of 32 (40.6%) patients in the tinnitus group and was normal in all of the control group. Abnormal caloric responses in patients with severe tinnitus were more frequent than in patients with mild or moderate tinnitus. There was a statistically significant difference in the optokinetic gain values between the tinnitus and control groups.
Conclusion: A relationship between tinnitus and abnormal caloric responses was determined. Tinnitus may be the first symptom of vestibular dysfunction
A bio-sensing platform utilizing a conjugated polymer, carbon nanotubes and PAMAM combination
In this study, amperometric biosensing performance of a novel platform utilizing a conducting polymer (CP), multi-walled carbon nanotubes (MWCNTs) and poly(amidoamine) (PAMAM) dendrimer was constructed. In order to fabricate the proposed biosensor, a graphite electrode was modified with poly[9,9-di-(2-ethylhexyl)-fluorenyl-2,7-diyl] end capped with N,N-bis(4-methylphenyl)-4-aniline (PFLA), MWCNTs and PAMAM, respectively. Then, GOx was immobilized onto the modified surface with the help of glutaraldehyde (GA) as the crosslinking reagent. Then, analytical and kinetic parameters of the constructed biosensor were investigated and the biosensor showed a linear response for glucose between 0.05 and 0.75 mM with a detection limit of 0.014 mM. K-M(app) and sensitivity values were calculated as 0.66 mM and 55.41 mu A mM(-1) cm(-2), respectively. To investigate the surface modifications, scanning electron microscopy (SEM) and cyclic voltammetry (CV) techniques were used. Finally, fabricated biosensor was tested on beverages for glucose detection successfully