Lei Aldir Blanc, política cultural imaterial e folia de reis em Santa Helena de Minas (MG)

The present study has as background the field of the immaterial Brazilian cultural heritage is expanding. Therefore, the article aims to analyze the impacts of the Aldir Blanc Law on immaterial cultural policy from one case: the promotion of a genealogical and socioanthropological research project of the Folia de Reis de Santa Helena de Minas. To this end, a methodology based on ethnography, interviews, analyses of documents and posts on social networks was mobilized. Based on a historical and socio-anthropological perspective, it was highlighted that the impacts were many, some unexpected and/or unplanned caused. So there has been a decentralisation of policies and resources. It is concluded, from the case analyzed, that the unexpected effects of the impact of the Law of this cultural policy could in future help to promote, safeguard and inventory Folia as a regional (and/or national) Brazilian cultural heritage.O presente estudo tem como pano de fundo o campo do patrimônio cultural brasileiro imaterial se encontra em expansão. Logo, o artigo tem por objetivo analisar os impactos da Lei Aldir Blanc na política cultural imaterial a partir de um caso: o fomento de um projeto de pesquisa genealógica e socioantropológica da Folia de Reis de Santa Helena de Minas. Para tanto foi mobilizada uma metodologia pautada na etnografia, em entrevistas, analises de documentos e de postagens em redes sociais. Com base numa perspectiva histórica e socioantropológica, destacou-se que os impactos foram muitos, alguns não esperados e/ou não planejados causados. Assim, houve uma descentralização das políticas e recursos. Conclui-se, a partir do caso analisado, que os efeitos não esperados do impacto da Lei dessa política cultural poderiam futuramente ajudar a promover, salvaguardar e inventariar a Folia como um patrimônio cultural regional (e/ou nacional) brasileiro

Interactions Between University-Company-Government and the Entrepreneurial Ecosystems: Systematic Literature Review

This research aimed to analyze how scientific and technological publications have characterized, in the last ten years, the interaction between university, business, government and entrepreneurial ecosystems for innovation. Therefore, a research was carried out whose objective was bibliographical in nature, with a qualitative, descriptive approach, covering the period from 2011 to the first quarter of 2021, using, for this purpose, the databases ScienceDirect and Scopus. Then, the results found were analyzed using the My-SAE and VOSViewer software. The results showed that there is a predominance of studies on university entrepreneurship and how the dissemination of knowledge learned in universities contributes to the sustainable development of entrepreneurial ecosystems through the emergence of new entrepreneurial agents. As research results, the entrepreneurial ecosystem with a complex adaptive system, the predominance of studies on university entrepreneurship, innovation, regional economy and sustainable development was presented

Novel treatment approaches to combat trichomoniasis, a neglected and sexually transmitted infection caused by trichomonas vaginalis : translational perspectives

The multistep translational science behind new drugs comprehends the entire process through laboratory, clinical, and community observations turned into health interventions. The development of new drug options from discovering targets and leading compounds in basic research for implementing therapeutic guidelines contributes to the emergence of health policies essential for infection control. This review updates the translational research in the scenario of the most common non-viral sexually transmitted infection (STI), trichomoniasis. Paradoxically to its high occurrence, it is considered neglected since notification is not mandatory. It turns into a stable disease with health complications, and receives little emphasis from public health programs to control STI. Although related to curable STIs, the current drugs, metronidazole and tinidazole, present therapeutic failures. The need for new options to treat trichomoniasis is established by basic research studies and patents revealing novel synthetic compounds and natural products presenting anti-Trichomonas vaginalis activities, mainly based on in vitro findings. Clinical trials are still focused on new routes of administration for conventional drugs. In addition, nanotechnology approaches are in their infancy, shedding light on potential possibilities for creating more effective, targeted, and safe delivery systems. Overall, the novel proposed approaches need, in addition to pharmaceutical development and efficacy assessments, to ensure that the quality requirements for their use as medicines are met. It is essential to overcome these issues to cross the “Death Valley” of drug discovery and to advance in the translational science criteria in the trichomoniasis drug development field

Memória e acervo: da trajetória de um projeto de extensão à constituição de um memorial

The Study of Heritage and Memory - NEP - the Federal University of Santa Maria develops research project about the japanese immigration in Santa Maria. From interviews with immigrants, realized the invisibility of this community in the state of Rio Grande do Sul. Aware of the undissociability between research and extension, the NEP has made the first exposition in honor of Japanese Immigration in Santa Maria, Rio Grande do Sul, celebrating 50 years of the arrival of the japaneses in the city and 100 years in Brazil. The exposition, temporary, and conducted in a space provided by the Secretariat of Culture of the city related the history of a group of people who dream with the quickly enrichment, but that ended up working on a semi- slave way in the city of Uruguaiana, west border of the State. The success of the exposition made the NEP to contact with other institutions of Japanese culture in the state to take the initiative of viabilization of a memorial to Japanese culture, once the actual state of Rio Grande do Sul does not have a museum or institution equivalent to preserving the history of the Japanese immigration.O Núcleo de Estudos do Patrimônio e Memória - NEP - da Universidade Federal de Santa Maria desenvolve um projeto de pesquisa sobre a imigração japonesa na cidade. A partir de entrevistas com os imigrantes, observou- se a invisibilidade desta comunidade no Estado do Rio Grande do Sul. Consciente da indissociabilidade entre pesquisa e extensão, o NEP realizou a 1ª Exposição em homenagem à Imigração Japonesa em Santa Maria, Rio Grande do Sul, comemorando os 50 anos de chegada dos nipônicos na cidade e 100 anos no Brasil. A exposição, de caráter temporário e realizada em um espaço cedido pela Secretaria de Cultura do município, contava a saga de um grupo de pessoas que sonhava com o enriquecimento rápido, mas que acabou trabalhando de forma semiescrava na cidade de Uruguaiana, fronteira oeste do estado. O sucesso da exposição levou o NEP a entrar em contato com outras instituições de cultura japonesa no estado para tomar a iniciativa de viabilização de um memorial de cultura japonesa, uma vez que o próprio estado do Rio Grande do Sul não conta com um museu ou instituição equivalente para a preservação da história da imigração nipônica

The Fat Giraffe, volume 1, number 3 (1969)

https://red.mnstate.edu/fatgiraffe/1003/thumbnail.jp

The potential therapeutic effect of guanosine after cortical focal ischemia in rats

Background and Purpose: Stroke is a devastating disease. Both excitotoxicity and oxidative stress play important roles in ischemic brain injury, along with harmful impacts on ischemic cerebral tissue. As guanosine plays an important neuroprotective role in the central nervous system, the purpose of this study was to evaluate the neuroprotective effects of guanosine and putative cerebral events following the onset of permanent focal cerebral ischemia. Methods: Permanent focal cerebral ischemia was induced in rats by thermocoagulation. Guanosine was administered immediately, 1 h, 3 h and 6 h after surgery. Behavioral performance was evaluated by cylinder testing for a period of 15 days after surgery. Brain oxidative stress parameters, including levels of ROS/RNS, lipid peroxidation, antioxidant nonenzymatic levels (GSH, vitamin C) and enzymatic parameters (SOD expression and activity and CAT activity), as well as glutamatergic parameters (EAAC1, GLAST and GLT1, glutamine synthetase) were analyzed. Results: After 24 h, ischemic injury resulted in impaired function of the forelimb, caused brain infarct and increased lipid peroxidation. Treatment with guanosine restored these parameters. Oxidative stress markers were affected by ischemic insult, demonstrated by increased ROS/RNS levels, increased SOD expression with reduced SOD activity and decreased nonenzymatic (GSH and vitamin C) antioxidant defenses. Guanosine prevented increased ROS/RNS levels, decreased SOD activity, further increased SOD expression, increased CAT activity and restored vitamin C levels. Ischemia also affected glutamatergic parameters, illustrated by increased EAAC1 levels and decreased GLT1 levels; guanosine reversed the decreased GLT1 levels and did not affect the EAAC1 levels. Conclusion: The effects of brain ischemia were strongly attenuated by guanosine administration. The cellular mechanisms involved in redox and glutamatergic homeostasis, which were both affected by the ischemic insult, were also modulated by guanosine. These observations reveal that guanosine may represent a potential therapeutic agent in cerebral ischemia by preventing oxidative stress and excitotoxicity

Esportividade, melancolia, nacionalismo e deficiência: a cobertura fotográfica dos jogos paralímpicos pelas lentes da Folha de São Paulo (1992 – 2016)

Esta pesquisa teve como objetivo caracterizar a representação imagética do esporte e dos atletas paraolímpicos na cobertura fotográfica do jornal Folha de São Paulo durante a realização dos Jogos Paralímpicos no período de 1992 a 2016. O estudo foi de cunho quanti-qualitativo, descritivo e exploratório e se baseou na teoria do enquadramento. Houve um aumento no número de fotografias publicadas no decorrer dos anos, sendo que algumas das características principais das fotos são: esportividade dos atletas; melancolia associada à deficiência; promoção de nacionalismo; e espetacularização do grotesco e do ciborgue. O caráter polissêmico das representações propagadas nas fotografias revela algumas das complexidades envolvidas nas formas de se conceber atletas com deficiência e a necessidade de se melhor qualificar a mídia para futuras coberturas do esporte paralímpico

Sportivity, melancolia, nationalism and disability: the photographic coverage of the paralympic games through the lenses of Folha de São Paulo (1992 - 2016)

This study aimed to characterize the image representation of sport and Paralympic athletes in the photographic coverage of the “Folha de São Paulo” newspaper during the Paralympic Games from 1992 to 2016. The study was quanti-qualitative, descriptive and exploratory and was based on the framework theory. There has been an increase in the number of photographs published over the years, and some of the main characteristics of the photos are: athletes' sportsmanship; melancholy associated with the deficiency; promotion of nationalism; and spectacularization of the grotesque, and the cyborg. The polysemous character of the representations propagated in the photographs reveals some of the complexities involved in conceiving disabled athletes and the need to better qualify the media for future coverage of Paralympic sport

Comunidade de joaninhas (Coleoptera: Coccinellidae) em consórcio de couve (Brassica oleraceae var. acephala) com coentro (Coriandrum sativum) sob manejo orgânico.

As abordagens agroecológicas de produção orgânica vegetal visam a diversificação dos cultivos, estimulando a persistência, a abundância e a diversidade de inimigos naturais que atuam no controle biológico de insetos-pragas. Nesse contexto, o presente estudo teve por objetivos determinar a diversidade e a estrutura da comunidade de joaninhas predadoras (Coleoptera: Coccinellidae) associados a pulgões em couve, cultivada em consórcio com coentro. O estudo foi realizado na unidade experimental de produção integrada lavoura-pecuária denominada de Sistema Integrado de Produção Agroecológica, SIPA, em Seropédica, RJ. Os tratamentos foram consórcio de couve com coentro e o monocultivo de couve. A diversidade de joaninhas foi determinada por meio da coleta de indivíduos através de amostragens por remoção. Um total de 25 espécies de joaninhas está presente no SIPA. Não houve infestação por pulgões na couve consorciada com coentro, o qual foi usado pelas joaninhas como sítio de alimentação, oviposição, abrigo para larvas, pupas e adultos, além de acasalamento

Levels of nutrients and aflatoxins in dry and extruded food to cats / Níveis de nutrientes e aflatoxinas em alimentos secos e extrudados para gatos

The present study aimed to compare the composition on the label of dry complete food for adult cats with the nutritional composition determined by chemical analysis, to determine the occurrence of aflatoxins, and to list the most used ingredients. The determined parameters were: crude protein (CP), ether extract in acid hydrolysis (EEA), mineral matter (MM), moisture (MO), crude fiber (CF), calcium (Ca), phosphorus (P), sodium (Na), calculated metabolizable energy (ME) and aflatoxins. In assessing the levels guaranteed on the label, MO, CP, CF, MM and P remained within the range, but with a variation on the limits. The metabolizable energy varied from 3,712 to 4,136 kcal/kg. There was a divergence in the levels of two diets, with Ca above and EE below the values declared on the label in relation to composition obtained by chemical analysis, and both non-compliant in 20% foods tested. Regarding sodium, the diets showed levels 130 - 384% higher than stated on the label. Aflatoxin was found in 90% samples from zero to 4.37 ppb. The wide variation observed in the composition within the same super premium segment can cause losses due to the lack or excess of essential nutrients for the animal