Investigation of cerebral autoregulation in the newborn piglet during anaesthesia and surgery

The relationship between cerebral autoregulation (CA) and the neurotoxic effects of anaesthesia with and without surgery is investigated. Newborn piglets were randomly assigned to receive either 6 h of anaesthesia (isoflurane) or the same with an additional hour of minor surgery. The effect of the spontaneous changes in mean arterial blood pressure (MABP) on the cerebral haemodynamics (oxy- and deoxy-haemoglobin, HbO2 and Hb) was measured using transverse broadband near-infrared spectroscopy (NIRS). A marker for impaired CA, concordance between MABP and intravascular oxygenation (HbD = HbO2 - Hb) in the ultra-low frequency domain (0.0018-0.0083 Hz), was assessed using coherence analysis. Presence of CA impairment was not significant but found to increase with surgical exacerbation. The impairment did not correlate with histological outcome (presence of cell death, apoptosis and microglial activation in the brain)

Comprehensive Literature Review on the Optimal Production of Naturally Produced Astaxanthin from Haematococcus pluvialis

Environmental conditions for the production of astaxanthin from Haematococcus pluvialis is illustrated in this comprehensive literature review. Naturally produced astaxanthin is becoming more viable with today’s advanced technology. The effects of cultivation methods, media, light, nutrients, aeration, salt, temperature, pH, and ultrasound on H. pluvialis were examined to provide insight on the optimal ways to grow and produceastaxanthin naturally for commercial production

A measurement of the S- and P-wave content of antiproton annihilation at rest into two pions in liquid deuterium

Based on our measurement of the ratio f(π-π0p)/f(π+π-n ) = 2.07±0.05 for antiproton annihilation at rest in liquid deuterium, and the most recent results on f(π0π0) for antiproton annihilation at rest in liquid hydrogen, we find that the S-wave annihilation of the antiproton on the proton or neutron is dominant. We find a 95% confidence level upper limit of 8% for the P-wave annihilation. Further details may be found in an earlier publication. © 1989