10,751 research outputs found

    Extra symmetries in the effective theory of heavy quarks

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    Extra symmetries are shown to exist in the effective theory of heavy quarks when both quarks and anti-quarks with the same velocity are included. These symmetries mix the quark with the anti-quark sector and they resemble axial-type of symmetries. Together with the known flavor and spin symmetries they form a u(4)u(4) algebra when a single flavor is considered. It is shown that the full U(4)U(4) set of symmetries breaks spontaneously down to U(2)⊗U(2) U(2) \otimes U(2). The Goldstone modes corresponding to the spontaneously broken currents are identified. Finally, the precise connection of this theory with the fundamental QCD is derived and it is investigated under some approximations. Some physical processes where these extra symmetries may be relevant are pointed out.Comment: 26 pages (two figures available upon request), tex file, UB-ECM-PF-93/

    Social Security Disability Insurance, Medicare And Work: A Review of the SSDI and Medicare Rules Related to Work Activity. Guidelines for Proactively Using the SSDI and Medicare Work Incentives to Help Individuals with Disabilities Maximize Independence Through Work

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    This policy-to-practice brief will focus on issues related to benefits and work for the SSDI beneficiary. After first explaining what SSDI is and the differences between SSDI and SSI, we will explain two historical work disincentives: the substantial gainful activity (SGA) rule and the continuing disability review (CDR). We will then explore a number of work incentives or special rules that seek to encourage work by either allowing benefits to continue for limited periods while working (trial work period (TWP), extended period of eligibility (EPE)), or allow individuals to quickly return to benefits status when a work effort stops or wage levels dip below the SGA level (expedited reinstatement). We will also explain special rules for either ignoring some short-term employment efforts (unsuccessful work attempts) or reducing countable monthly wages to be measured against the SGA amount for the year in question (impairment related work expenses, subsidies, paid time off)

    The Medicaid Buy-In for Working People With Disabilities: Individuals With Disabilities Can Earn Significant Wages and Qualify for This Important Health Care Benefit

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    This policy-to-practice brief provides an in-depth illustrated description of the Plan for Achieving Self-Support (PASS) work incentives. This brief reviews how the PASS can be used to promote a work goal; the criteria for approving a PASS; and how the PASS can be used in conjunction with other programs to promote and achieve vocational success. Throughout the brief, examples are used to illustrate principles and provide an example in the appendices to show how to propose a PASS that meets all of SSA’s criteria for approval. Extensive citations to law, regulation, and policy appear in footnotes to maximize the usefulness of this publication to benefits planners who are engaged in writing PASS proposals for individuals

    WORKING: The Newsletter of the New York Makes Work Pay Initiative

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    WELCOME to the inaugural issue of Working, a print and elec¬tronic newsletter produced by the New York Makes Work Pay Initiative. This Initiative is a Comprehensive Employment Ser¬vices Medicaid Infrastructure Grant funded by the U.S. Department of Health and Human Services, Centers for Medicare and Medicaid Services (CMS) to the New York State Office of Mental Health (OMH) and its management partners the Burton Blatt Institute (BBI) at Syra¬cuse University and the Employment and Disability Institute (EDI) at Cornell University. The New York Makes Work Pay Initiative is currently funded for calendar years 2009 and 2010 and will provide an array of services to individuals with disabilities, the agencies and advocates that serve them, and employers, helping to remove obstacles to work and pave the way to self-supporting employment

    Diffusion in a Granular Fluid - Simulation

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    The linear response description for impurity diffusion in a granular fluid undergoing homogeneous cooling is developed in the preceeding paper. The formally exact Einstein and Green-Kubo expressions for the self-diffusion coefficient are evaluated there from an approximation to the velocity autocorrelation function. These results are compared here to those from molecular dynamics simulations over a wide range of density and inelasticity, for the particular case of self-diffusion. It is found that the approximate theory is in good agreement with simulation data up to moderate densities and degrees of inelasticity. At higher density, the effects of inelasticity are stronger, leading to a significant enhancement of the diffusion coefficient over its value for elastic collisions. Possible explanations associated with an unstable long wavelength shear mode are explored, including the effects of strong fluctuations and mode coupling

    Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells

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    Indexación: Scopus.Departamento de Oncología Básico-Clínica, Facultad de Medicina, Universidad de Chile, Santiago, Chile 2Comisión Chilena de Energía Nuclear, Santiago, Chile 3Center for Research and Applications in Plasma Physics and Pulsed Power, P4, Chile 4Departamento de Ciencias Físicas, Universidad Andres Bello, Santiago, Chile 5Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Santiago, Chile 6Current Address: Center of Excellence in Precision Medicine, Pfizer, Chile. on IR responsive modeling. This work was supported by Anillo grant ACT1115 and ACT172101, PIA Program, CONICYT; the Chilean doctoral fellowship 21130246Enhanced radiosensitivity at low doses of ionizing radiation (IR) (0.2 to 0.6 Gy) has been reported in several cell lines. This phenomenon, known as low doses hyperradiosensitivity (LDHRS), appears as an opportunity to decrease toxicity of radiotherapy and to enhance the effects of chemotherapy. However, the effect of low single doses IR on cell death is subtle and the mechanism underlying LDHRS has not been clearly explained, limiting the utility of LDHRS for clinical applications. To understand the mechanisms responsible for cell death induced by low-dose IR, LDHRS was evaluated in DLD-1 human colorectal cancer cells and the expression of 80 microRNAs (miRNAs) was assessed by qPCR array. Our results show that DLD-1 cells display an early DNA damage response and apoptotic cell death when exposed to 0.6 Gy. miRNA expression profiling identified 3 over-expressed (miR-205-3p, miR-1 and miR-133b) and 2 downregulated miRNAs (miR-122-5p, and miR-134-5p) upon exposure to 0.6 Gy. This miRNA profile differed from the one in cells exposed to high-dose IR (12 Gy), supporting a distinct low-dose radiation-induced cell death mechanism. Expression of a mimetic miR- 205-3p, the most overexpressed miRNA in cells exposed to 0.6 Gy, induced apoptotic cell death and, more importantly, increased LDHRS in DLD-1 cells. Thus, we propose miR-205-3p as a potential radiosensitizer to low-dose IR. © Andaur et al.http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25405&path[]=7956

    The “New” Ticket to Work and Self-Sufficiency Program: Enhancing Economic Self-Sufficiency of Beneficiaries through Work Opportunities and Public/Private Partnership

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    Discusses the history of the Social Security Administration’s Vocational Rehabilitation and describes the intents and functioning of the Ticket to Work and work Incentives Improvement Act of 1999. This publication is based on federal Social Security and Supplemental Security Income (SSI) laws, regulations and policy. Following Sections I and II pertaining to historical context and evolution of SSA and the Ticket, information presented regarding the operations and structure of the Ticket to Work and Self-Sufficiency Program is based exclusively on the new 2008 regulations

    Tomography of high-redshift clusters with OSIRIS

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    High-redshift clusters of galaxies are amongst the largest cosmic structures. Their properties and evolution are key ingredients to our understanding of cosmology: to study the growth of structure from the inhomogeneities of the cosmic microwave background; the processes of galaxy formation, evolution, and differentiation; and to measure the cosmological parameters (through their interaction with the geometry of the universe, the age estimates of their component galaxies, or the measurement of the amount of matter locked in their potential wells). However, not much is yet known about the properties of clusters at redshifts of cosmological interest. We propose here a radically new method to study large samples of cluster galaxies using microslits to perform spectroscopy of huge numbers of objects in single fields in a narrow spectral range-chosen to fit an emission line at the cluster redshift. Our objective is to obtain spectroscopy in a very restricted wavelength range (~100 A in width) of several thousands of objects for each single 8x8 square arcmin field. Approximately 100 of them will be identified as cluster emission-line objects and will yield basic measurements of the dynamics and the star formation in the cluster (that figure applies to a cluster at z~0.50, and becomes ~40 and ~20 for clusters at z~0.75 and z~1.00 respectively). This is a pioneering approach that, once proven, will be followed in combination with photometric redshift techniques and applied to other astrophysical problems.Comment: 4 pages, 3 figures. Proceedings of "Science with the GTC", Granada (Spain), February 2002, RMxAA in pres
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