Diterpenoids from the roots of Salvia sclarea

The roots of Salvia sclarea yielded two triterpenoids, 3-oxo-oleanolic acid, alpha-amyrin, a steroid sitosterol and 12 diterpenoids, two of which are new. The known diterpenoids are ferruginol, salvipisone, microstegiol, candidissiol, 2,3-dehydrosalvipisone, aethiopinone, 1-oxoaethiopinone, salvinolone, cryptojaponol, Delta(7)-manool, and the new compounds are sclareapinone and acetylsalvipisone. The structures were established by spectral data and also by TLC comparison for the known compounds. Copyright (C) 1997 Elsevier Science Ltd

Constituents of Salvia verticillata

Three new and fourteen known compounds were isolated from the roots of Salvia verticillata L. Spectral methods were used for the structure determination besides TLC comparisons with authentic samples for the known compounds

Terpenoids and flavonoids from Salvia cyanescens

The following compounds have been identified in the aerial parts of Salvia cyanescens: a new diterpenoid 12-isopentenyl-3-oxosalvipisone, two sesquiterpenes caryophyllene oxide, spathulenol, five diterpenes diterpenes manoyl oxide, 11 beta-hydroxymanoyl oxide, ferruginol, aethiopinone and salvipisone, three triterpenes alpha-amyrin, alpha-amyrin 3-acetate and lupeol 3-acetate as well as sitosterol and four flavonoids salvigenin, 6-hydroxyapigenin-7,4'-dimethyl ether, 6-hydroxykaempferol-3,6-dimethyl ether and kaempferol-3,7-dimethyl ether. (C) 1997 Elsevier Science Ltd

Diterpenoids and triterpenoids from Salvia multicaulis

Two new diterpenoids, 3-oxo-12-methoxy-14-hydroxyabieta-8, 11,13-triene and 6-oxo-12-peroxyabieta-8,11,13-triene, a new steroid brassicasterone and a new aromatic ester 4,4'-bisbenzoic acid heptyl ester were obtained from the roots of Salvia multicaulis. In addition six known triterpenoids, six diterpenoids and sitosterol were identified. (C) 1998 Elsevier Science Ltd. All rights reserved

Prolonged Cholestasis due to Infection with Hepatitis A: Case Report

Atypical forms of hepatitis A infection may be seen in adults. Steroid therapy is an up-to-date treatment that can be applied in patients with prolonged cholestasis. In this report a patient with prolonged cholestasis after acute HAV infection has been presented

Comparison of Three Different Anti-retroviral Regimens in Terms of Immunological and Virological Response

Introduction: After introduction of highly active anti-retroviral treatment (HAART), the mortality and morbidity rates among HIV/AIDS patients have been reduced. CD4+ T cell and HIV RNA measurement is important in the follow-up during the treatment. The aim of this study was to evaluate three different ART regimens in terms of immunological and virological response

ABIETANE DITERPENES FROM SALVIA-NAPIFOLIA

From the acetone extract of the roots of Salvia napifolia, eight known diterpenoids-horminone, 7-acetyl-horminone, ferruginol, pachystazone, cryptanol, cryptojaponol, sugiol and microstegiol-and five new diterpenes-6,1 2, 14-trihydroxyabieta-6,8, 11,12-tetraen, 7,20-epoxyroyleanone, 1-oxoferruginol, 6-oxoferruginol and 1 1,12-dioxoabieta-8,13-dien- were obtained. The structures of the new and the known compounds were established by spectral methods

Norditerpenoid alkaloids from Delphinium pyrimadale

From the aerial parts of Delphinium pyrimadale a new norditerpenoid alkaloid, 8-acetylcondelphine, has been isolated, together with the known alkaloids isotalatizidine, condelphine and senbusine C. The structure of the new alkaloid was established on the basis of H-1, C-13, APT, DEFT homonuclear COSY, HETCOR and COLOC NMR spectral studies and by chemical reactions. (C) 1998 Published by Elsevier Science Ltd. All rights reserved

Diterpenoid alkaloids from Delphinium uncinatum

From the aerial parts of Delphinium uncinatum a new diterpenoid uncinatine and four known norditerpenoid alkaloids have been isolated. By spectral data (H-1 and C-13 NMR) the known compounds were established as 14-acetylperegrine, 14-acetylvirescenine, condelphine and delbrusine. The structure of the new alkaloid was deduced by 1D and 2D NMR techniques. (C) 1998 Elsevier Science Ltd. All rights reserved