A PILOT STUDY OF PIPPALYADI TAILA YONIPICHU IN THE MANAGEMENT OF KAPHAJA YONIYVAPAD (NON-SPECIFIC VAGINITIS)

Background: Vaginitis is an inflammatory process involving the vagina, expanding often to the contiguous anatomical structures (cervix and vulva). Non-specific vaginitis is usually caused by an alteration (disruption) of the normal vaginal microflora, usually represented by the presence of Lactobacilli. Nonspecific vaginitis can be correlated to Kaphaja Yonivyapad based on its Lakshanas. Objectives: To evaluate the efficacy of Pippalyadi taila yoni Pichu in management of Kaphaja yoni vyapad. Design: This was a pilot study that included twenty female patients of Kaphaja yonivyapad (non specific vaginitis) from the Dept. of Prasooti tantra and Stree roga OPD of Rajiv Gandhi educational society’s Ayurvedic Medical College, Ron. Patients were administered Pippalyadi taila yonipichu for 7 days and were assessed before and after the treatment and followed up on the 14th day. Results: This pilot study showed statistically significant changes in reduction of Katishoola (p<0.001), Kandu (p<0.001), consistency of the srava (p<0.001) and Srava pramana (quantity of the discharge) (p<0.001) showing the effectiveness of Pippalyadi taila yoni Pichu in the management of Kaphaja yonivyapad. Conclusions: Pippalyadi taila yonipichu showed significant changes in the management of Kaphaja yoni Vyapad with the reduction of Katishoola, Kandu, consistency of the Srava and Srava pramana after the treatment

Awareness of contraception in post-partum women in a tertiary care centre

Background: In this modern or scientific era even though women are working equally or one step ahead of men, in family planning decision they are still lagging behind. Postpartum period is very crucial for a woman especially for many of those belonging to the villages as this may be the only time she comes in contact with a health personnel and in a mood to listen health advice. Keeping this in mind, this crucial period was considered as opportunity to test the issue of awareness regarding contraception.Methods: We conducted a cross-sectional study in the department of obstetrics and gynecology of Govt medical college and hospital, Aurangabad between August 2016 to December 2016. A total 720 post-partum women were interrogated and counselled regarding various methods of contraception.Results: Only 55.69% were aware about various methods of contraception. Awareness was maximum for Sterilisation (91%) followed by Intrauterine contraceptive device (81%) and Oral contraceptive pills (41%). Women knew about contraception from health care system (45%) and mass media (36%). After counselling 97% patients ready to use.Conclusions: There is lack of awareness regarding contraception. Contraceptive services are to be strengthened by intergrating with antenatal sevices

Study of interleukin-6 levels in early diagnosis of neonatal sepsis

Background:Neonatal septicemia is one of the commonest causes of neonatal mortality and morbidity. Interleukin-6 Levels appears to be one of the most promising candidate cytokine for early diagnosis of neonatal septicaemia. The aim and objectives of this study was to study the role of IL-6 levels as an early marker for diagnosis of neonatal sepsis and to compare IL-6 levels with other septic markers.  Methods:This is a hospital based prospective study to evaluate the efficacy of IL-6 as an early diagnostic marker of neonatal sepsis. Eighty neonates, delivered in the hospital, having risk factors for neonatal sepsis, along with those coming to hospital with signs and symptoms of sepsis up to 28 days of life (as study group ) along with normal new-borns admitted to the postnatal ward without high risk factors (control group) were enrolled for this study.Results:IL-6 Levels has shown maximum sensitivity of 95.83%, specificity of 87.50%, positive predictive value of 92%, negative predictive value of 93.33% and accuracy of 92.50 %. E. coli was the most common organism responsible for sepsis. CRP was reported to be highly sensitive (84.21%), and  CBC was highly specific (75.00%), IT ratio has sensitivity of 62.5% and specificity of 56.25% while micro-ESR has shown sensitivity of 50.0% and specificity of 62.5%. Out of 80 cases, blood culture (BacTalert) showed growth in 48 cases in study group while two cases in control group. Thus blood culture positivity was 60%.Conclusion:IL-6 test has maximum sensitivity as well as specificity in comparison with other septic markers. Blood culture is the gold standard for the diagnosis of septicemia. CRP is most sensitive while CBC is most specific marker in neonatal sepsis.

Rheumatoid Arthritis: Severity Classification, Factors Responsible, Pathophysiology, Current and Herbal Treatment

Rheumatoid Arthritis is the autoimmune disorder occurs due to the change in life style, improper diet plans, smoking, excessive alcohol consumption etc. It generally affects the joints and creates swelling and severe pain in joints which leads to further destruction of bone and cartilages. Due to autoimmune responses the factors like Tumor Necrosis Factor-α, Interleukins-1 are introduced to synovial and synovial membrane which creates the swelling and pain. These factors further produce reactive oxygen species and inducing osteoclasts which destruct the bone and cartilages. Along with the drugs the several natural herbal treatments are also available for the treatment of rheumatoid arthritis. This includes varies medicinal plants form which acacia species is more potent and efficient. Acacia Senegal is the plant which blocks the receptors and decreases the level of tumor necrosis factor-α. Present work on rheumatoid arthritis mainly covers classification, factors responsible, pathophysiology, severity, current treatment and its drawbacks, herbal treatment and its benefits in treatment of Rheumatoid Arthritis

Not Available

Not AvailableThe study assesses noise hazards in agri-based industrial workplaces in Punjab state of India. Guidelines of Canadian Centre for Occupational Health and Safety were employed to generate the primary data on noise survey. Potential noise hazardous areas within 40 agri-based industrial units (flour units/wheat milling units) were identified through constructing the contour map. A layout mentioning the locations of various machines and workers in the units were prepared. Data on output capacity, size of power source, maintenance condition of machines and workroom configurations were solicited through the personal interview of the owner of the units. Semi-structured interview schedule was prepared to generate the primary data. Average temperature, relative humidity and air velocity in the working rooms were also recorded. A specific grid (2 m × 2 m) was made on the layout based on the size of unit to get representative data for unit. A sound-level meter was also placed to record the noise levels. It was observed that the normal working hours (h) of flour units were varied from 8 to 12 h. The highest sound level was generated at power transmission unit varying in the range of 92.2 dBA and 98.5 dBA. The average sound intensity was recorded as 95.1 dBA which was the highest noise intensity. For ensuring the safe working environment, noise control devices should be provided to all workers in the units and need to be enforced. The machines should be regularly maintained to reduce warbling of components which increase noise and employers should consider reduction in working period to minimize noise exposure period. Personal protective measures for the safety of workers are also needed.Not Availabl

<span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Luminescence of Cu⁺ in Na₂SO₄</span>

235-240Cu+ doped Na2SO4 was synthesized and Cu+ emission has been studied. The changes in luminescence of Cu+ with the phase of Na2SO4 are shown. The luminescence from phase III is observed at 357 nm while the phase V shows emission around 396 nm. Thus shift of almost 40 nm is observed. The excitations are also different and observed at 254 nm for phase III and 270 nm for phase V. Phase I, which is hexagonal shows emission at 456 nm with the excitation at 245 nm

Prevention of Parent to Child Transmission (PPTCT) program data in India: an emerging data set for appraising the HIV epidemic.

BACKGROUND: Evidence based resource allocation and decentralized planning of an effective HIV/AIDS response requires reliable information on levels and trends of HIV at national and sub-national geographic levels. HIV sentinel surveillance data from antenatal clinics (HSS-ANC) has been an important data source to assess the HIV/AIDS epidemic in India, but has a number of limitations. We assess the value of Prevention of Parent to Child Transmission (PPTCT) programme data to appraise the HIV epidemic in India. METHODS/FINDINGS: HIV data from PPTCT sites were compared to HSS-ANC and general population level surveys at various geographic levels in the states of Karnataka, Maharashtra and Andhra Pradesh. Chi-square tests were used to ascertain statistical significance. PPTCT HIV prevalence was significantly lower than HSS-ANC HIV prevalence (0.92% vs. 1.22% in Andhra Pradesh, 0.65% vs. 0.89% in Karnataka, 0.52% vs. 0.60% in Maharashtra, p<0.001 for all three states). In all three states, HIV prevalence from PPTCT centres that were part of the sentinel surveillance was comparable to HSS-ANC prevalence but significantly higher than PPTCT centres that were not part of the sentinel surveillance. HIV prevalence from PPTCT data was comparable to that from general population surveys. In all three states, significant declines in HIV prevalence between 2007 and 2010 were observed with the PPTCT data set. District level analyses of HIV trends and sub-district level analysis of HIV prevalence were possible using the PPTCT and not the HSS-ANC data sets. CONCLUSION: HIV prevalence from PPTCT may be a better proxy for general population prevalence than HSS-ANC. PPTCT data allow for analysis of HIV prevalence and trends at smaller geographic units, which is important for decentralized planning of HIV/AIDS programming. With further improvements to the system, India could replace its HSS-ANC with PPTCT programme data for surveillance

Comparison of HSS-ANC and PPTCT data sets in three high-prevalence South Indian states, 2008.

<p>Comparison of HSS-ANC and PPTCT data sets in three high-prevalence South Indian states, 2008.</p

HIV prevalence among ANC women tested in PPTCT centers at district (Andhra Pradesh, Karnataka, Maharashtra, and Tamil Nadu) and sub-district levels (Karnataka), 2009.

<p>HIV Prevalence ranges are indicated by color. Lines indicate boundaries at district (graph on right) and sub-district (graph on left) levels.</p

Comparison of NFHS-3 and PPTCT data in three high-prevalence South Indian states, 2005–06.

<p>N, total number of individuals tested.</p><p>p-value for HIV prevalence comparison.</p