191 research outputs found

    Equiangular tight frames and fourth root seidel matrices

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    AbstractIn this paper we construct complex equiangular tight frames (ETFs). In particular, we study the grammian associated with an ETF whose off-diagonal entries consist entirely of fourth roots of unity. These ETFs are classified, and we also provide some computational techniques which give rise to previously undiscovered ETFs

    A FAST MODEL FOR FLOW AND POLLUTANT DISPERSION AT THE NEIGHBOURHOOD SCALE

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    This paper deals with the development of a simple urban model for flow and dispersion in the urban canopy layer (UCL). The flow module of the model calculates spatially-averaged wind profiles adopting a technique recently proposed in the literature, which is based on a balance equation between the obstacle drag force and the local shear stress. Spatially-averaged wind profiles are used as input for a newly proposed dispersion model which solves the advection-diffusion equation at neighbourhood scale. In the model, the effects of the buildings within the UCL are taken into account by means of morphological parameters λf and λp (the ratios of plan area and frontal area of buildings to the lot area). Spatially-averaged mean concentrations output by the developed model are compared with numerical results obtained from the computational fluid dynamics (CFD) model FLUENT. In particular, two configurations of constant height UCL have been considered, which refer to as λp = λf = 0.16 and λp = λf = 0.44. The originality of the study is that the dispersion model itself integrates the equations without explicitly resolving the flow around individual buildings but still accounts for their effects. The computational costs are much reduced which makes it suitable for the predictions of concentrations over the neighbourhood scale in an operational context

    Osteonecrosis of the jaws in patients assuming oral bisphosphonates for osteoporosis: A retrospective multi-hospital-based study of 87 Italian cases

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    BACKGROUND: Bisphosphonates (BPs) are currently the chief drugs for the prevention/treatment of osteoporosis; one of their adverse effects is the osteonecrosis of the jaw (BRONJ). The primary endpoints of this multi-center cross-sectional study are: i) an observation of the clinical features of BRONJ in 87 osteoporotic, non-cancer patients; and ii) an evaluation of their demographic variables and comorbidities. METHODS: 87 BRONJ patients in therapy for osteoporosis with BPs from 8 participating clinical Italian centers were consecutively identified and studied. After BRONJ diagnosis and staging, comorbidities and data relating to local and drug-related risk factors for BRONJ were collected. RESULTS: 77/87 (88.5%) patients in our sample used alendronate as a BP type; the duration of bisphosphonate therapy ranged from 2 to 200 months, and 51.7% of patients were in treatment for ≤ 38 months (median value). No comorbidities or local risk factors were observed in 17 (19.5%) patients, indicating the absence of cases belonging to BRONJ forms triggered by surgery. BRONJ localization was significantly associated with age: an increased risk of mandible localization (p=0.002; OR=6.36, 95%CI=[1.89; 21.54]) was observed for those over 72 yrs. At multivariate analysis, the increased risk of BRONJ in the mandible for people over 72 yrs (OR'=6.87, 95%CI=[2.13; 2.21]) was confirmed for a BP administration >56 months (OR'=4.82, 95%CI=[2.13; 22.21]). CONCLUSION: Our study confirms the fundamental necessity of applying protocols of prevention in order to reduce the incidence of BRONJ in osteoporotic, non-cancer patients in the presence of comorbidities and/or local risk factor as well as, less frequently, in their absence

    A FAST MODEL FOR FLOW AND POLLUTANT DISPERSION AT THE NEIGHBOURHOOD SCALE

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    This paper deals with the development of a simple urban model for flow and dispersion in the urban canopy layer (UCL). The flow module of the model calculates spatially-averaged wind profiles adopting a technique recently proposed in the literature, which is based on a balance equation between the obstacle drag force and the local shear stress. Spatially-averaged wind profiles are used as input for a newly proposed dispersion model which solves the advection-diffusion equation at neighbourhood scale. In the model, the effects of the buildings within the UCL are taken into account by means of morphological parameters λf and λp (the ratios of plan area and frontal area of buildings to the lot area). Spatially-averaged mean concentrations output by the developed model are compared with numerical results obtained from the computational fluid dynamics (CFD) model FLUENT. In particular, two configurations of constant height UCL have been considered, which refer to as λp = λf = 0.16 and λp = λf = 0.44. The originality of the study is that the dispersion model itself integrates the equations without explicitly resolving the flow around individual buildings but still accounts for their effects. The computational costs are much reduced which makes it suitable for the predictions of concentrations over the neighbourhood scale in an operational context

    Oncological outcomes in fertility-sparing treatment in stage IA-G2 endometrial cancer

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    Background: The gold standard treatment for early-stage endometrial cancer (EC) is hysterectomy with bilateral salpingo-oophorectomy (BSO) with lymphadenectomy. In selected patients desiring pregnancy, fertility-sparing treatment (FST) can be adopted. Our review aims to collect the most incisive studies about the possibility of conservative management for patients with grade 2, stage IA EC. Different approaches can be considered beyond demolition surgery, such as local treatment with levonorgestrel-releasing intra-uterine device (LNG-IUD) plus systemic therapy with progestins. Study design: Our systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. PubMed, EMBASE, and Scopus databases were consulted, and five studies were chosen based on the following criteria: patients with a histological diagnosis of EC stage IA G2 in reproductive age desiring pregnancy and at least one oncological outcome evaluated. Search imputes were “endometrial cancer” AND “fertility sparing” AND “oncologic outcomes” AND “G2 or stage IA”. Results: A total of 103 patients were included and treated with a combination of LNG-IUD plus megestrol acetate (MA) or medroxyprogesterone acetate (MPA), gonadotrophin-releasing hormone (GnRH) plus MPA/MA, hysteroscopic resectoscope (HR), and dilation and curettage (D&C). There is evidence of 70% to 85% complete response after second-round therapy prolongation to 12 months. Conclusions: Conservative measures must be considered temporary to allow pregnancy and subsequently perform specific counseling to adopt surgery. Fertility-sparing management is not the current standard of care for young women with EC. It can be employed for patients with early-stage diseases motivated to maintain reproductive function. Indeed, the results are encouraging, but the sample size must be increased

    Leftovers:The presence of manufacture-derived aquatic lipids in Alaskan Pottery

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    Lipids preserved within the walls of ancient pottery vessels are routinely analysed to reveal their original contents. The provenience of aquatic lipids in pottery is generally connected to vessel function (e.g., for cooking or storing fish, shellfish and aquatic mammals). However, ethnographic reports from early historic Alaska mention the use of aquatic oils for waterproofing low-fired pottery. Results of lipid residue studies on Alaskan pottery reflect an exclusive function of pottery to process aquatic resources. However, can one be sure these residues are the product of vessel function and not a remnant of the manufacturing process? The study presents the results of an experiment where the preservation of aquatic lipids during the firing process at different temperatures was measured. It was found that nearly all lipids were removed at firing temperatures of ≥ 400°C. Petrographic analysis of Alaskan pottery samples indicates that firing temperatures were generally &gt; 550°C but &lt; 800°C. The contribution of pre-firing manufacture-derived lipids to samples fired at these temperatures may be regarded as negligible. While the possible presence of aquatic lipids from post-firing surface treatments cannot be excluded, such treatments appear unnecessary for well-fired pottery.</p
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