Impact of an educational intervention on smoking counseling practice among Nigerian dentists and dental students

Introduction: Oral health professionals are important in smoking cessation and prevention as their role is very crucial given the impact of smoking on oral health. Therefore, dental professionals need adequate education in tobacco use prevention and cessation skills to increase their confidence and be able to help patients to quit smoking. This study was aimed at determining the impact of an educational intervention on the attitudes, willingness, and perceived barriers of a group of Nigerian dental students and dentists to smoking cessation counseling in the dental clinic.Methods: A self.administered questionnaire.based study was conducted in September 2007 at the Lagos University Teaching Hospital Idi Araba, Lagos. This was followed by a series of lectures and seminars using the brief intervention strategies for patients willing to quit using the Ask, Advise, Assess, Assist, and Arrange of cessation. A repeat study was conducted in January 2009 using the same questionnaire. Post intervention attitudes were significantly improved over pre intervention values for each parameter used in the assessment.Results: A significantly higher proportion of the respondents were  interested in providing cessation services after the intervention (P = 0.00002). Most (83.1%) of the respondents were willing to undergo training with a slight increase in the post intervention group from 80.9% to 86%. All the reported barriers were significantly reduced after the intervention (P = 0.000).Conclusion: This study has shown that educational interventions such as didactic instructions and practical training in tobacco use cessation can help to increase the willingness, confidence, and ability to provide information, during encounters with patients.Key words: Educational intervention, dental students, dentists, Nigeria, smoking cessatio

Access to oral health care for HIV patients in Nigeria: Role of attending physicians

Objective: To assess the knowledge of attending physicians on oral manifestations of HIV infection and their attitude and practice towards dental referral for HIV patients. Method: A self-administered questionnaire survey of attending physicians in outpatient clinics of two teaching hospitals in Lagos and the National hospital, Abuja. Results: seventy-eight (78) doctors returned questionnaires. 16 of them (20.5%) could list correctly three oral lesions in HIV infection, 40 (51.3%) listed two, 18 (23.1%) listed one while 4 (5.1%) could not list any. In managing oral health complaints by patients, 59 (75.5%) agreed that their patients had complained of oral symptoms, of these, only 18 had ever referred a patient for dental care. Majority (84.6%) agreed that HIV patients should have regular dental check ups. Conclusion: The education of both patients and health providers in Nigeria on the importance of good oral health in the quality of life of the HIV patient is necessary. HIV patients in Nigeria should be referred for dental checkups and prophylaxis at least twice a year Key Words: Access; oral health; HIV; physician. African Journal of Oral Health Vol.1(1) 2004: 37-4

A Pilot test of an oral health education module for community health workers in Ikeja LGA, Lagos State.

Objectives: The purpose of this paper is to report the experience of developing, facilitating, and evaluating a 3-day module on oral health education for Primary Health Care Workers (CHW) in Ikeja LGA Lagos State.Methods: Twenty-one CHW in Ikeja LGA were invited for a 3-day oral health education-training program in January 2015. An oral health education manual and a flip chart developed for this purpose were used during training. Participants received didactic lectures on the first two days and participated in a practical session on the third day. A pretest was done before the training session while a posttest was done immediately and 6 months after the intervention. Data entry, validation and analysis was done using SPSS version 20.Results: Majority of the respondents were female (95.0%), Community Health Officers (65.0%), mean age was 42.1± 10.4 years while mean years of experience was 9.7 ±10.8 years. There was a statistically significant increase (p= 0.000) in the mean knowledge score of participants immediately after the intervention. There was no difference between the results obtained immediately and at 6 months after the training (p= 0.328). All participants reported including oral health education in their routine health education sessions at the 6-month review. They also reported observing changes in client's perception and behavior regarding oral health. They identified the flipchart as a useful tool for the oral health education sessions in the PHC.Conclusion: PHC workers can be easily trained and deployed as oral health educatorsparticularly in areas where there is shortage of oral health care workers.Keywords: oral health; oral health education; primary health care; community health workers

Vascular Reactivity and Salt Sensitivity in Normotensive and Hypertensive Adult Nigerians

There are not many studies designed to study the relationship between vascular reactivity and salt sensitivity in a black population. Fifty-two hypertensive (HT) and forty-seven age-matched normotensive (NT) Nigerian subjects took part in the study after informed consent was obtained from them. Ethical clearance was obtained from the College of Medicine of the University of Lagos. Vascular hyperreactivity in response to the Cold Pressor Test (CPT) was determined as a change in systolic blood pressure (ΔSBP) or diastolic blood pressure (ΔDBP) ≥ +15mmHg. This was determined before and after salt-loading with 200mmol Na+/day for 5 days. Salt sensitivty was determined as a change in mean arterial blood pressure (ΔMABP) ≥+5mmHg. Salt-loading led to significant increases in SBP among NT (p = 0.03) and among HT (p = 0.0001) subjects; DBP increased significantly only among HT subjects (p = 0.0003). Systolic and diastolic hyperreactivity were higher among HT (49% and 39% respectively) compared to NT (44% and 39% respectively) at baseline. However systolic hyperreactivity (SHP) increased from 44% to 64% after salt-loading among the NT while diastolic hyperreactivity (DHP) reduced from 39% to 36%. Among the HT, both SHP and DHP reduced from 49% to 33% and from 41% to 31% respectively following salt-loading. Salt sensitivity was higher among HT (56%) compared to NT 34%. Salt sensitivity was positively correlated with systolic reactivity before salt (r = 0.33; p < 0.05) and after salt (r = 0.25; p > 0.05) but negatively correlated with diastolic reactivity before salt (r = -0.38; p < 0.05) and after salt (r = -0.40; p < 0.05) among NT. These results suggest that systolic hyperreactivity may be a significant determinant in the development of salt sensitive hypertension among this population.Keywords: Vascular reactivity, Salt sensitivity hypertension, Blood pressur

Correlates of illness behaviour related to orofacial infections of odontogenic origin among adults in a semi urban community in Nigeria

Background: Infections of facial spaces in the maxillofacial region occur in most cases as a complication of odontogenic infections. It often results in substantial morbidity, with serious and potentially life threatening outcomes if allowed to progress without prompt medical attention.Objective: To identify factors that determine illness behaviour related to maxillofacial space infections.Method: This was a descriptive cross-sectional study of adult residents of pakoto community, Ifo local government area, Ogun state. The study was conducted using an interviewer administered questionnaire which included key information about respondents’ awareness of predisposing factors of maxillofacial space infections; common actions takenwith regards to treatment, and the factors that influenced their utilization of the available oral health care service.Results: A total of 187 individuals were sampled, mean age was 30.5(SD 11.7) years with majority being females (59.4%) The proportion of the total respondents who reported a history suggestive of orofacial space infection was 20.3% (n=38). Visiting a patent medicine dealer (26.3%) along with visiting a dentist (31.6%) were the illness behaviours most frequently engaged in by respondents who have had an orofacial swelling following a toothache, with majority (73.7%) indicating the action they took was based on what was most convenient.Conclusion: This study has revealed that engagement in unorthodox practises by individuals in a semi-urban community studied is prevalent, and influenced by factors such as age, gender, level of education and occupation.Keywords: Odontogenic infection, semi-urban community, illness behaviourFunding: Non

Determinants of preventive oral health behaviour among senior dental students in Nigeria

BACKGROUND: To study the association between oral health behaviour of senior dental students in Nigeria and their gender, age, knowledge of preventive care, and attitudes towards preventive dentistry. METHODS: Questionnaires were administered to 179 senior dental students in the six dental schools in Nigeria. The questionnaire obtained information on age, gender, oral self-care, knowledge of preventive dental care and attitudes towards preventive dentistry. Attending a dental clinic for check-up by a dentist or a classmate within the last year was defined as preventive care use. Students who performed oral self-care and attended dental clinic for check-ups were noted to have complied with recommended oral self-care. Chi-square test and binary logistic regression models were used for statistical analyses. RESULTS: More male respondents agreed that the use of fluoride toothpaste was more important than the tooth brushing technique for caries prevention (P < 0.001). While the use of dental floss was very low (7.3%), more females were more likely to report using dental floss (p=0.03). Older students were also more likely to comply with recommended oral self-care (p<0.001). In binary regression models, respondents who were younger (p=0.04) and those with higher knowledge of preventive dental care (p=0.008) were more likely to consume sugary snacks less than once a day. CONCLUSION: Gender differences in the awareness of the superiority of using fluoridated toothpaste over brushing in caries prevention; and in the use of dental floss were observed. While older students were more likely to comply with recommended oral self-care measures, younger students with good knowledge of preventive dental care were more likely to consume sugary snacks less than once a day

Fragile Mental Retardation Protein Interacts with the RNA-Binding Protein Caprin1 in Neuronal RiboNucleoProtein Complexes

Fragile X syndrome is caused by the absence of the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein. FMRP is associated with messenger RiboNucleoParticles (mRNPs) present in polyribosomes and its absence in neurons leads to alteration in synaptic plasticity as a result of translation regulation defects. The molecular mechanisms by which FMRP plays a role in translation regulation remain elusive. Using immunoprecipitation approaches with monoclonal Ab7G1-1 and a new generation of chicken antibodies, we identified Caprin1 as a novel FMRP-cellular partner. In vivo and in vitro evidence show that Caprin1 interacts with FMRP at the level of the translation machinery as well as in trafficking neuronal granules. As an RNA-binding protein, Caprin1 has in common with FMRP at least two RNA targets that have been identified as CaMKIIα and Map1b mRNAs. In view of the new concept that FMRP species bind to RNA regardless of known structural motifs, we propose that protein interactors might modulate FMRP functions

Elevated Levels of the Vesicular Monoamine Transporter and a Novel Repetitive Behavior in the Drosophila Model of Fragile X Syndrome

Fragile X Syndrome (FXS) is characterized by mental impairment and autism in humans, and it often features hyperactivity and repetitive behaviors. The mechanisms for the disease, however, remain poorly understood. Here we report that the dfmr1 mutant in the Drosophila model of FXS grooms excessively, which may be regulated differentially by two signaling pathways. Blocking metabotropic glutamate receptor signaling enhances grooming in dfmr1 mutant flies, whereas blocking the vesicular monoamine transporter (VMAT) suppresses excessive grooming. dfmr1 mutant flies also exhibit elevated levels of VMAT mRNA and protein. These results suggest that enhanced monoamine signaling correlates with repetitive behaviors and hyperactivity associated with FXS

Argonaute2 Suppresses Drosophila Fragile X Expression Preventing Neurogenesis and Oogenesis Defects

Fragile X Syndrome is caused by the silencing of the Fragile X Mental Retardation gene (FMR1). Regulating dosage of FMR1 levels is critical for proper development and function of the nervous system and germ line, but the pathways responsible for maintaining normal expression levels are less clearly defined. Loss of Drosophila Fragile X protein (dFMR1) causes several behavioral and developmental defects in the fly, many of which are analogous to those seen in Fragile X patients. Over-expression of dFMR1 also causes specific neuronal and behavioral abnormalities. We have found that Argonaute2 (Ago2), the core component of the small interfering RNA (siRNA) pathway, regulates dfmr1 expression. Previously, the relationship between dFMR1 and Ago2 was defined by their physical interaction and co-regulation of downstream targets. We have found that Ago2 and dFMR1 are also connected through a regulatory relationship. Ago2 mediated repression of dFMR1 prevents axon growth and branching defects of the Drosophila neuromuscular junction (NMJ). Consequently, the neurogenesis defects in larvae mutant for both dfmr1 and Ago2 mirror those in dfmr1 null mutants. The Ago2 null phenotype at the NMJ is rescued in animals carrying an Ago2 genomic rescue construct. However, animals carrying a mutant Ago2 allele that produces Ago2 with significantly reduced endoribonuclease catalytic activity are normal with respect to the NMJ phenotypes examined. dFMR1 regulation by Ago2 is also observed in the germ line causing a multiple oocyte in a single egg chamber mutant phenotype. We have identified Ago2 as a regulator of dfmr1 expression and have clarified an important developmental role for Ago2 in the nervous system and germ line that requires dfmr1 function