Limited operating conditions of the jet mill injector

Наведено три критичні режими роботи інжектору струминного млина та показано умови їх виникнення. Знайдено коефіцієнти інжекції щодо розглянутих критичних режимів.Представлены три критических режима работы инжектора струйной мельницы и показаны условия их возникновения. Найдены коэффициента инжекции, соответствующие рассмотренным критическим режимам.Представлены три критических режима работы инжектора струйной мельницы и показаны условия их возникновения. Найдены коэффициента инжекции, соответствующие рассмотренным критическим режимам

On the Problem of Standardization of the Technique of Normative Legal Acts

The active development of public relations, the formation of new areas requiring legislative regulation, leads to the adoption of a large number of normative legal acts. The work is carried out in a short time, the practice of “batch” acceptance of documents is widespread, which reduces the quality of regulatory legal acts. Along with this, the terminological apparatus is growing, which leads to contradictions between acts, gaps in legislation. Issues of legal technique require regulatory and methodological reinforcement. This actualizes the adoption of the Federal Law on Regulatory Acts in the Russian Federation, taking into account the study of the shortcomings that were made in previous bills

ДИНАМИКА ПОКАЗАТЕЛЕЙ ЦИТОКИНОВОГО СТАТУСА БОЛЬНЫХ ХРОНИЧЕСКИМ СОЧЕТАННЫМ ГЕПАТИТОМ В+С ПРИ ПРОВЕДЕНИИ ПРОТИВОВИРУСНОЙ ТЕРАПИИ

The author studied the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy. The examination embraced 49 patients aged from 18 to 47 years (pegylated interferon- alfa2а and ribavirin were used in 24 patients). It is established, that a significant increase of the interferon-α, interferon-γ, tumor necrosis factor-α (with following decrease of tumor necrosis factor-α) in blood serum content in patients with a stable virusologic response serves as an early criterion of the antiviral therapy effectiveness.Изучен цитокиновый статус у пациентов с хроническ м сочетанным гепатитом В+С в процессе противовирусной терапии. Обследованы 49 больных в возрасте от 18 до 47 лет (пегилированный интерферональфа2а и рибавирин были назначены 24 пациентам). Установлено, что значительное повышение содержания интерферона-α, интерферона-γ и фактора некроза опухоли-α (с последующим снижением) в сыворотке крови у больных с устойчивым вирусологическим ответом служит ранним критерием эффективности противовирусной терапии

Justification of the program therapy of acute hepatitis C

Treatment of acute hepatitis C remains one of the main problems of modern hepatology. There are many variants of treatment, but there is no common opinion about scheme and time of onset of the therapy. From the other hand, early treatment can prevent chronisation in more than 70% of cases. Specific therapy was used 135 patients with acute hepatitis C aged from 16 to 52 years (26,5+0,7 years). Our analysis has shown, that its better to start specific therapy on the second month of the disease with -interferon monotherapy by induction scheme

Markers of restenosis after percutaneous transluminal balloon angioplasty in patients with critical limb ischemia

Among cardiovascular diseases, chronic obliterating lesions of the arteries of lower extremities, which are one of the important problems of modern healthcare, are distinguished. In most cases, the cause of damage to the arteries of lower extremities is atherosclerosis. The most severe form is chronic ischemia, characterized by pain at rest and ischemic ulcers, ultimately increasing the risk of limb loss and cardiovascular mortality. Therefore, patients with critical limb ischemia need limb revascularization. Percutaneous transluminal balloon angioplasty is one of the least invasive and safe approaches, with advantages for patients with comorbidities. However, after this procedure, restenosis is still possible. Early detection of changes in the composition of some molecules as markers of restenosis will help screen patients at the risk of restenosis, as well as find ways to apply efforts for further directions of inhibition of this process. The purpose of this review is to provide the most important and up-to-date information on the mechanisms of restenosis development, as well as possible predictors of their occurrence. The information collected in this publication may be useful in predicting outcomes after surgical treatment and will also find new ways for the target implication to the mechanisms of development of restenosis and atherosclerosis