Perubahan Fungsi Ruang Domestik di Sekitar Kampus Unpaz (Universidade Da Paz), Dili, Timor Leste

Universidade da Paz (UNPAZ) didirikan oleh Fundação Neon Metin (FNM) pada 9 Maret 2004, dan juga merupakan universitas swasta terbesar yang ada di Timor Leste saat ini. UNPAZ sangat berkembang dari segi pengembangan kampus (infrastruktur) maupun meningkatnya jumlah mahasiswa. Perkembangan kampus ini menyebabkan terjadinya Perubahan fungsi ruang pada Kampus UNPAZ. Selain kampus Perubahan fisik dan fungsi ruang domestik terjadi pada kampung sekitarnya, terutama Kampung Osindo I Manleuana. Kampung Osindo I Manleuana secara geografis terletak di Kelurahan Fatuhada, Kecamatan Dom-Aleixo, Kotamadya Dili, Timor Leste. Kampung ini mula-mula penduduknya bermata pencaharian sebagai petani. Letak kampung dekat jalur akses utama menuju Kampus UNPAZ menyebabkan kegiatan ekonomi penduduk menjadi berubah. Perubahan ini menyebabkan terjadinya Perubahan fungsi ruang domestik pada rumah tinggal maupun halamannya. Untuk meneliti lebih jauh lagi tentang proses Perubahan fungsi ruang domestik dengan kehadirannya Kampus UNPAZ, digunakan pendekatan penelitian kualitatif, dengan teknik pengumpulan data melalui observasi, wawancara, dokumentasi dan pembagian kuesioner pada masyarakat setempat. Perubahan-Perubahan fungsi ruang domestik di atas dianalisis dengan teori-teori yang relevan yaitu Perubahan fisik, ruang, bentuk ruang, dan pola organisasi ruang

Estimation and validation of temporal gait features using a markerless 2D video system

Background and Objective: Estimation of temporal gait features, such as stance time, swing time and gait cycle time, can be used for clinical evaluations of various patient groups having gait pathologies, such as Parkinson’s diseases, neuropathy, hemiplegia and diplegia. Most clinical laboratories employ an optoelectronic motion capture system to acquire such features. However, the operation of these systems requires specially trained operators, a controlled environment and attaching reflective markers to the patient’s body. To allow the estimation of the same features in a daily life setting, this paper presents a novel vision based system whose operation does not require the presence of skilled technicians or markers and uses a single 2D camera. Method: The proposed system takes as input a 2D video, computes the silhouettes of the walking person, and then estimates key biomedical gait indicators, such as the initial foot contact with the ground and the toe off instants, from which several other temporal gait features can be derived. Results: The proposed system is tested on two datasets: (i) a public gait dataset made available by CASIA, which contains 20 users, with 4 sequences per user; and (ii) a dataset acquired simultaneously by a marker-based optoelectronic motion capture system and a simple 2D video camera, containing 10 users, with 5 sequences per user. For the CASIA gait dataset A the relevant temporal biomedical gait indicators were manually annotated, and the proposed automated video analysis system achieved an accuracy of 99% on their identification. It was able to obtain accurate estimations even on segmented silhouettes where, the state-of-the-art markerless 2D video based systems fail. For the second database, the temporal features obtained by the proposed system achieved an average intra-class correlation coefficient of 0.86, when compared to the "gold standard" optoelectronic motion capture system. Conclusions: The proposed markerless 2D video based system can be used to evaluate patients’ gait without requiring the usage of complex laboratory settings and without the need for physical attachment of sensors/markers to the patients. The good accuracy of the results obtained suggests that the proposed system can be used as an alternative to the optoelectronic motion capture system in non-laboratory environments, which can be enable more regular clinical evaluations.info:eu-repo/semantics/acceptedVersio

Impacto do fogo na macrofauna e insetos sociais do solo.

Resumo 5

Liver haemangioma: common and uncommon findings and how to improve the differential diagnosis

Haemangiomas are common focal liver lesions, generally detected in the work-up of asymptomatic patients. From the pathological point of view, they can be classified as small (capillary) or large, with cavernous vascular spaces that may show thrombosis, calcifications and hyalinisation. The polymorphic imaging appearance of haemangiomas depends on their histological features and flow pattern. The widespread use of cross-sectional imaging has allowed an increased detection rate and a better characterisation of this benign tumour. Recent developments of ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) providing high spatial and temporal resolution, together with the use of new contrast agents and/or pulse sequences has broadened the spectrum of imaging findings, contributing to diagnostic refinement in difficult cases. The scope of the present article is to provide an overview of the range of appearances of haemangiomas, explored with recent cross-sectional imaging modalities, emphasising its atypical findings as explored by temporally resolved contrast-enhanced imaging

The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/VIRGO GW170817. V. Rising X-ray Emission from an Off-Axis Jet

We report the discovery of rising X-ray emission from the binary neutron star (BNS) merger event GW170817. This is the first detection of X-ray emission from a gravitational-wave source. Observations acquired with the Chandra X-ray Observatory (CXO) at t~2.3 days post merger reveal no significant emission, with L_x<=3.2x10^38 erg/s (isotropic-equivalent). Continued monitoring revealed the presence of an X-ray source that brightened with time, reaching L_x\sim 9x10^39 erg/s at ~15.1 days post merger. We interpret these findings in the context of isotropic and collimated relativistic outflows (both on- and off-axis). We find that the broad-band X-ray to radio observations are consistent with emission from a relativistic jet with kinetic energy E_k~10^49-10^50 erg, viewed off-axis with theta_obs~ 20-40 deg. Our models favor a circumbinary density n~ 0.0001-0.01 cm-3, depending on the value of the microphysical parameter epsilon_B=10^{-4}-10^{-2}. A central-engine origin of the X-ray emission is unlikely. Future X-ray observations at $t\gtrsim 100$ days, when the target will be observable again with the CXO, will provide additional constraints to solve the model degeneracies and test our predictions. Our inferences on theta_obs are testable with gravitational wave information on GW170817 from Advanced LIGO/Virgo on the binary inclination.Comment: 7 Pages, 4 Figures, ApJL, In Press. Keywords: GW170817, LV

Estimation of interdomain flexibility of N-terminus of factor H using residual dipolar couplings

Characterization of segmental flexibility is needed to understand the biological mechanisms of the very large category of functionally diverse proteins, exemplified by the regulators of complement activation, that consist of numerous compact modules or domains linked by short, potentially flexible, sequences of amino acid residues. The use of NMR-derived residual dipolar couplings (RDCs), in magnetically aligned media, to evaluate interdomain motion is established but only for two-domain proteins. We focused on the three N-terminal domains (called CCPs or SCRs) of the important complement regulator, human factor H (i.e. FH1-3). These domains cooperate to facilitate cleavage of the key complement activation-specific protein fragment, C3b, forming iC3b that no longer participates in the complement cascade. We refined a three-dimensional solution structure of recombinant FH1-3 based on nuclear Overhauser effects and RDCs. We then employed a rudimentary series of RDC datasets, collected in media containing magnetically aligned bicelles (disk-like particles formed from phospholipids) under three different conditions, to estimate interdomain motions. This circumvents a requirement of previous approaches for technically difficult collection of five independent RDC datasets. More than 80% of conformers of this predominantly extended three-domain molecule exhibit flexions of < 40 °. Such segmental flexibility (together with the local dynamics of the hypervariable loop within domain 3), could facilitate recognition of C3b via initial anchoring and eventual reorganization of modules to the conformation captured in the previously solved crystal structure of a C3b:FH1-4 complex