Rewiring strategies for changing environments

A typical pervasive application executes in a changing environment: people, computing resources, software services and network connections come and go continuously. A robust pervasive application needs adapt to this changing context as long as there is an appropriate rewiring strategy that guarantees correct behavior. We combine the MERODE modeling methodology with the ReWiRe framework for creating interactive pervasive applications that can cope with changing environments. The core of our approach is a consistent environment model, which is essential to create (re)configurable context-aware pervasive applications. We aggregate different ontologies that provide the required semantics to describe almost any target environment. We present a case study that shows a interactive pervasive application for media access that incorporates parental control on media content and can migrate between devices. The application builds upon models of the run-time environment represented as system states for dedicated rewiring strategies

Temperature dependent dynamic and static magnetic response in magnetic tunnel junctions with Permalloy layers

Ferromagnetic resonance and static magnetic properties of CoFe/Al2O3/CoFe/Py and CoFe/Al2O3/CoFeB/Py magnetic tunnel junctions and of 25nm thick single-layer Permalloy(Py) films have been studied as a function of temperature down to 2K. The temperature dependence of the ferromagnetic resonance excited in the Py layers in magnetic tunnel junctions shows knee-like enhancement of the resonance frequency accompanied by an anomaly in the magnetization near 60K. We attribute the anomalous static and dynamic magnetic response at low temperatures to interface stress induced magnetic reorientation transition at the Py interface which could be influenced by dipolar soft-hard layer coupling through the Al2O3 barrier

MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study

© Published by the BMJ Publishing Group Limited. Introduction Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms. Patients who experience prolonged periods of uncontrolled asthma have a higher incidence of exacerbations and increased morbidity and mortality rates. The ability to determine and to predict levels of asthma control and the occurrence of exacerbations is crucial in asthma management. Therefore, we aimed to determine to what extent physiological, behavioural and environmental data, obtained by mobile healthcare (mHealth) and home-monitoring sensors, as well as patient characteristics, can be used to predict episodes of uncontrolled asthma and the onset of asthma exacerbations. Methods and analysis In an 1-year observational study, patients will be provided with mHealth and home-monitoring systems to record daily measurements for the first-month (phase I) and weekly measurements during a follow-up period of 11 months (phase II). Our study population consists of 150 patients, aged ≥18 years, with a clinician's diagnosis of asthma, currently on controller medication, with uncontrolled asthma and/or minimally one exacerbation in the past 12 months. They will be enrolled over three participating centres, including Leiden, London and Manchester. Our main outcomes are the association between physiological, behavioural and environmental data and (1) the loss of asthma control and (2) the occurrence of asthma exacerbations. Ethics This study was approved by the Medical Ethics Committee of the Leiden University Medical Center in the Netherlands and by the NHS ethics service in the UK. Trial registration number NCT02774772

The effect of the application of mono-lauric acid with glycerol mono-laurate in weaned piglets, on the use of antimicrobials in sow herds

The Dutch government has obliged the pig industry to reduce the use of antimicrobials at farm level with 50% by 2013. The search for alternatives for antimicrobials and other tools which can improve the health status of the farm is intensified. One example of an alternative for antimicrobials is Daafit, a combination of lauric acid and glycerol-mono-laurate, produced by the firm Daavision B.V.

Livestock diseases threatening smallholder farmers in Lao people's Democratic Republic

Purpose: In Lao People's Democratic Republic, uncontrolled animal trade, lack of animal containment and limited access to veterinary services are a growing-ground for virus spread. Foot-and-Mouth Disease (FMD) and several avian viruses are enzootic and threaten subsistence farmers. We assessed the (sero-)prevalence of several livestock viruses, and evaluated the knowledge, attitude, and practice of smallholder farmers towards FMD. Methods & Materials: In 2018, sera were collected from 394 domestic ruminants and screened using an ELISA that differentiates between infected and vaccinated animals. Questionnaires (n = 101) were statistically explored to identify knowledge gaps and risk factors related to FMD. In addition, oral and cloacal swabs, collected from 619 backyard poultry in 2011, 2014 and 2015, were tested by PCR for Newcastle disease (NDV), Influenza A, Coronavirus (CoV) and Chicken Anemia Virus (CAV). 206 poultry sera were screened by ELISA for the presence of anti-NDV and –Influenza A antibodies. Statistical and phylogenetic analyses revealed the viral infection patterns. Results: Although most farmers had very limited knowledge about FMD, many could correctly enumerate the symptoms and observed outbreaks recently. This was confirmed by our laboratory analysis: overall 37.1% of the animals were seropositive and 72.3% of the farms had at least one seropositive animal. Approx. 90% of the farmers reported that FMD negatively affects livestock trade and health. Moreover, we found high positivity rates of CoV and CAV RNA in cloacal and oral swabs (CoV: 38.3% and 6.2%; CAV: 16.1% and 1.7%). Younger animals were more likely to shed both, CoV and CAV, and similar virus strains co-circulated in chickens and ducks. Despite serological evidence of NDV and influenza A circulation (86.9% and 1.9%), viral RNA was detected in none of the swabs. Conclusion: A large proportion of the Lao population relies on subsistence livestock production which is, as shown here, severely compromised by the circulating viruses. To secure their livelihoods, vaccination programmes should target all susceptible hosts and achieve a high coverage throughout the country. These campaigns should be complemented by community-based sensitization to raise the awareness about prevention strategies, such as quarantine and trade restrictions

Numerical investigation of crack self-sealing in cement-based composites with superabsorbent polymers

Recently the concept of crack self-sealing has been investigated as a method to prevent degradation and/or loss of functionality of cracked concrete elements. To obtain self-sealing effect in the crack, water swelling admixtures such as superabsorbent polymers (SAP) are added into the cementitious mix. In order to design such self-sealing systems in an efficient way, a three-dimensional mesoscale numerical model is proposed to simulate capillary absorption of water in sound and cracked cement-based materials containing SAP. The numerical results yield the moisture content distribution in cracked and sound domain, as well as the absorption and swelling of SAP embedded in the matrix and in the crack. The performance of the model was validated by using experimental data from the literature, as well as experimentally-informed input parameters. The validated model was then used to investigate the role of SAP properties and dosage in cementitious mixtures, on the water penetration into the material from cracks. Furthermore different crack widths were considered in the simulations. The model shows good agreement with experimental results. From the numerical investigation guidelines are suggested for the design of the studied composites

Finite-size scaling in thin Fe/Ir(100) layers

The critical temperature of thin Fe layers on Ir(100) is measured through M\"o{\ss}bauer spectroscopy as a function of the layer thickness. From a phenomenological finite-size scaling analysis, we find an effective shift exponent lambda = 3.15 +/- 0.15, which is twice as large as the value expected from the conventional finite-size scaling prediction lambda=1/nu, where nu is the correlation length critical exponent. Taking corrections to finite-size scaling into account, we derive the effective shift exponent lambda=(1+2\Delta_1)/nu, where Delta_1 describes the leading corrections to scaling. For the 3D Heisenberg universality class, this leads to lambda = 3.0 +/- 0.1, in agreement with the experimental data. Earlier data by Ambrose and Chien on the effective shift exponent in CoO films are also explained.Comment: Latex, 4 pages, with 2 figures, to appear in Phys. Rev. Lett

MyAirCoach: the use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; study protocol of an observational study.

INTRODUCTION: Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms. Patients who experience prolonged periods of uncontrolled asthma have a higher incidence of exacerbations and increased morbidity and mortality rates. The ability to determine and to predict levels of asthma control and the occurrence of exacerbations is crucial in asthma management. Therefore, we aimed to determine to what extent physiological, behavioural and environmental data, obtained by mobile healthcare (mHealth) and home-monitoring sensors, as well as patient characteristics, can be used to predict episodes of uncontrolled asthma and the onset of asthma exacerbations. METHODS AND ANALYSIS: In an 1-year observational study, patients will be provided with mHealth and home-monitoring systems to record daily measurements for the first-month (phase I) and weekly measurements during a follow-up period of 11 months (phase II). Our study population consists of 150 patients, aged ≥18 years, with a clinician's diagnosis of asthma, currently on controller medication, with uncontrolled asthma and/or minimally one exacerbation in the past 12 months. They will be enrolled over three participating centres, including Leiden, London and Manchester. Our main outcomes are the association between physiological, behavioural and environmental data and (1) the loss of asthma control and (2) the occurrence of asthma exacerbations. ETHICS: This study was approved by the Medical Ethics Committee of the Leiden University Medical Center in the Netherlands and by the NHS ethics service in the UK. TRIAL REGISTRATION NUMBER: NCT02774772

Shell chemistry of the boreal Campanian bivalve Rastellum diluvianum (Linnaeus, 1767) reveals temperature seasonality, growth rates and life cycle of an extinct Cretaceous oyster

This is the final version. Available from European Geosciences Union (EGU) / Copernicus Publications via the DOI in this record. The Campanian age (Late Cretaceous) is characterized by a warm greenhouse climate with limited land-ice volume. This makes this period an ideal target for studying climate dynamics during greenhouse periods, which are essential for predictions of future climate change due to anthropogenic greenhouse gas emissions. Well-preserved fossil shells from the Campanian (±78 Ma) high mid-latitude (50∘ N) coastal faunas of the Kristianstad Basin (southern Sweden) offer a unique snapshot of short-term climate and environmental variability, which complements existing long-term climate reconstructions. In this study, we apply a combination of high-resolution spatially resolved trace element analyses (micro-X-ray fluorescence – µXRF – and laser ablation inductively coupled plasma mass spectrometry – LA-ICP-MS), stable isotope analyses (IRMS) and growth modeling to study short-term (seasonal) variations recorded in the oyster species Rastellum diluvianum from the Ivö Klack locality. Geochemical records through 12 specimens shed light on the influence of specimen-specific and ontogenetic effects on the expression of seasonal variations in shell chemistry and allow disentangling vital effects from environmental influences in an effort to refine paleoseasonality reconstructions of Late Cretaceous greenhouse climates. Growth models based on stable oxygen isotope records yield information on the mode of life, circadian rhythm and reproductive cycle of these extinct oysters. This multi-proxy study reveals that mean annual temperatures in the Campanian higher mid-latitudes were 17 to 19 ∘C, with winter minima of ∼13 ∘C and summer maxima of 26 ∘C, assuming a Late Cretaceous seawater oxygen isotope composition of −1 ‰ VSMOW (Vienna standard mean ocean water). These results yield smaller latitudinal differences in temperature seasonality in the Campanian compared to today. Latitudinal temperature gradients were similar to the present, contrasting with previous notions of “equable climate” during the Late Cretaceous. Our results also demonstrate that species-specific differences and uncertainties in the composition of Late Cretaceous seawater prevent trace element proxies (Mg∕Ca, Sr∕Ca, Mg∕Li and Sr∕Li) from being used as reliable temperature proxies for fossil oyster shells. However, trace element profiles can serve as a quick tool for diagenesis screening and investigating seasonal growth patterns in ancient shells.Flemish Institute for Science and Technology (IWT)Hercules InfrastructureFWOBelspo BRAIN ProjectCarlsbergfondetVUB Strategic Research