66 research outputs found
The Resilience of Hegemonic Salaryman Masculinity : A comparison of three prominent masculinities
It was the aim of this thesis to explore whether salaryman masculinity has lost its status as hegemonic form of masculinity to otaku masculinity or herbivore masculinity. The thesis makes use of the theoretical framework of hegemonic masculinity as first used by R.W. Connell. In order to assess changes in masculinity, sixteen semi-structured in-depth interviews have been conducted with students, both male and female, from Waseda University in Tokyo, Japan. The main findings of the research were that other than what a great deal of literature on hegemonic masculinity in Japan suggests, the salaryman lifestyle still serves as a powerful ideal in the lives of young students, and that otaku and herbivore masculinity have not taken over the hegemonic status of salaryman masculinity. The fact that it has been suggested otherwise was found to be mostly due to misguided understandings of what the terms otaku and ‘herbivore man’ mean, which in its turn is due to poor ethnological grounding and lack of an emic perspective
Registration accuracy for MR images of the prostate using a subvolume based registration protocol
<p>Abstract</p> <p>Background</p> <p>In recent years, there has been a considerable research effort concerning the integration of magnetic resonance imaging (MRI) into the external radiotherapy workflow motivated by the superior soft tissue contrast as compared to computed tomography. Image registration is a necessary step in many applications, e.g. in patient positioning and therapy response assessment with repeated imaging. In this study, we investigate the dependence between the registration accuracy and the size of the registration volume for a subvolume based rigid registration protocol for MR images of the prostate.</p> <p>Methods</p> <p>Ten patients were imaged four times each over the course of radiotherapy treatment using a T2 weighted sequence. The images were registered to each other using a mean square distance metric and a step gradient optimizer for registration volumes of different sizes. The precision of the registrations was evaluated using the center of mass distance between the manually defined prostates in the registered images. The optimal size of the registration volume was determined by minimizing the standard deviation of these distances.</p> <p>Results</p> <p>We found that prostate position was most uncertain in the anterior-posterior (AP) direction using traditional full volume registration. The improvement in standard deviation of the mean center of mass distance between the prostate volumes using a registration volume optimized to the prostate was 3.9 mm (p < 0.001) in the AP direction. The optimum registration volume size was 0 mm margin added to the prostate gland as outlined in the first image series.</p> <p>Conclusions</p> <p>Repeated MR imaging of the prostate for therapy set-up or therapy assessment will both require high precision tissue registration. With a subvolume based registration the prostate registration uncertainty can be reduced down to the order of 1 mm (1 SD) compared to several millimeters for registration based on the whole pelvis.</p
Dosimetric uncertainties related to the elasticity of bladder and rectal walls: Adenocarcinoma of the prostate
Purpose. - Radiotherapy is an important treatment for prostate cancer.During
treatment sessions, bladder and rectal repletion is difficult to quantify and
cannot be measured with a single and initial CT scan acquisition. Some methods,
such as image-guided radiation therapy and dose-guided radiation therapy, aimto
compensate thismissing information through periodic CT acquisitions. The aimis
to adapt patient's position, beam configuration or prescribed dose for a
dosimetric compliance. Methods. -We evaluated organmotion (and repletion) for
54 patients after having computed the original ballistic on a new CT scan
acquisition. A new delineation was done on the prostate, bladder and rectum to
determine the newdisplacements and define organ dosesmistakes (equivalent
uniformdose, average dose and dose-volume histograms). Results. - The new CT
acquisitions confirmed that bladder and rectal volumes were not constant during
sessions. Some cases showed that previously validated treatment plan became
unsuitable. A proposed solution is to correct dosimetries when bladder volume
modifications are significant. The result is an improvement for the stability
of bladder doses, D50 error is reduced by 25.3%, mean dose error by 5.1% and
equivalent uniform dose error by 2.6%. For the rectum this method decreases
errors by only 1%. This process can reduce the risk of mismatch between the
initial scan and following treatment sessions. Conclusion. - For the
proposedmethod, the cone-beamCT is necessary to properly position the isocenter
and to quantify bladder and rectal volume variation and deposited doses. The
dosimetries are performed in the event that bladder (or rectum) volume
modification limits are exceeded. To identify these limits, we have calculated
that a tolerance of 10% for the equivalent uniformdose (compared to the initial
value of the first dosimetry), this represents 11% of obsolete dosimetries for
the bladder, and 4% for the rectum
Distinct effects of rectum delineation methods in 3D-confromal vs. IMRT treatment planning of prostate cancer
BACKGROUND: The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate cancer was evaluated. MATERIALS AND METHODS: In a retrospective planning study 3-field, 4-field and IMRT treatment plans were analyzed for ten patients with localized prostate cancer. The dose to the rectum was evaluated based on dose-volume histograms of 1) the entire rectal volume (DVH) 2) manually delineated rectal wall (DWH) 3) rectal wall with 3 mm wall thickness (DWH(3)) 4) and the rectal surface (DSH). The influence of the rectal filling and of the seminal vesicles' anatomy on these dose parameters was investigated. A literature review of the dose-volume relationship for late rectal toxicity was conducted. RESULTS: In 3D-CRT (3-field and 4-field) the dose parameters differed most in the mid-dose region: the DWH showed significantly lower doses to the rectum (8.7% ± 4.2%) compared to the DWH(3 )and the DSH. In IMRT the differences between dose parameters were larger in comparison with 3D-CRT. Differences were statistically significant between DVH and all other dose parameters and between DWH and DSH. Mean doses were increased by 23.6% ± 8.7% in the DSH compared to the DVH in the mid-dose region. Furthermore, both the rectal filling and the anatomy of the seminal vesicles influenced the relationship between the dose parameters: a significant correlation of the difference between DVH and DWH and the rectal volume was seen in IMRT treatment. DISCUSSION: The method of delineating the rectum significantly influenced the dose representation in the dose-volume histogram. This effect was pronounced in IMRT treatment planning compared to 3D-CRT. For integration of dose-volume parameters from the literature into clinical practice these results have to be considered
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