The development of a novel large area building integrated solar collector for pool heating

Unglazed solar collectors have often been used a means of providing low cost heating to swimming pools. However, these systems are typically polymer style “mats” that are laid on top of a roof, often leading to poor aesthetics due to their lack of integration with the building itself. This study charts the development of a novel large area unglazed building integrated solar pool heating system (BIT), based on long run sheet metal roofing, from its initial conceptualisation through to its implementation. It discusses the design of the building integrated solar collector modules, the assessment of their performance through theoretical modelling and experimental validation. Subsequently, it shows the scaling of laboratory scale testing to a large area array through modelling and discusses the performance of the system in the “as-built” configuration. In doing this, it provides a succinct illustration of the design process for the development of the University of Waikato’s building integrated pool heating system

Guadecitabine, in combination with Cyclophosphamide, promotes anti- cancer immunity in BALB/c mice bearing 4T1 mouse mammary carcinoma

Background: The extremely high mortality rate of patients diagnosed with triple negative breast cancer makes it one of the deadliest forms of cancer. Due to the heterogenous nature of tumors, complete clearance is not achieved and clonal selection occurs resulting in tumor cells evading the immune system. I aim to design a therapeutic intervention that is able to elicit an effective immune response against the tumor and instill immunological memory to eradicate primary and metastatic lesions. I hypothesize that the combination of Guad and Cyp will synergize and promote anticancer immunity via increased expression of neo-tumor antigens and depletion of MDSCs and T-regs. Methods: Guadecitabine (Guad), is a second-generation DNA methyltransferase inhibitor (DMNTi) that has been reported to increase antigenicity and deplete myeloid-derived suppressor cells (MDSC’s). Cyclophosphamide (Cyp) is a chemotherapy that has been shown to deplete regulatory T-cells (T-regs). Both MDSD’s and T-regs suppress antitumor immunity. BALB/c mice were challenged with 4T1 tumor cells subcutaneously in the mammary fat pad region. 4T1-bearing mice were administered low-dose Guad and Cyp for ten consecutive days. Tumor growth curves, tumor-infiltrating lymphocytes (TILs) were measured and MDSC’s and T- regs levels were assessed by flow cytometry. Results: Results from this experiment showed significant synergy between Guad and Cyp with both drugs reducing the tumor size over monotherapy. Conclusions: Further analysis of the data along with future experiments will elucidate if this synergy is driven by the depletion of MDSC’s and T-regs alone or the increase in tumor antigenicity inducing increased numbers of TILs.https://scholarscompass.vcu.edu/gradposters/1078/thumbnail.jp

Hazards, Culture and Indigenous Communities: Final Project Report

This is the Final Report of the Hazards, Culture and Indigenous Communities (HCIC) project. This project considered the challenges and opportunities arising out of engagements between Indigenous peoples and natural hazard and land management government agencies in southern Australia. The majority of this activity has focused on cultural burning, which has also been our focus. Significantly, there is very limited existing research about these engagements, and limited public sector experience in engaging with Indigenous peoples. This constrains evidenced-based policy and practice and practitioner decision making. This lack of capacity was clear in the responses to the 2019-20 bushfires. The natural hazard sector is now required to do this retrospective and forward-looking learning, to foster more culturally safe natural hazard mitigation, and better connect the logics of hazards, risk and resilience. We undertook qualitative research, primarily through forming partnerships with key practitioners working in this space and undertaking research activities that iteratively learnt from these partnerships. In this, researching both Indigenous and non-indigenous values has been important in order to navigate and analyse this intercultural context. Our research findings are structured in two sections: the first presents the results from our literature review, the second presents a synthesis of the research findings arranged under six headings, as listed below, with recommended first steps for the natural hazard sector under each heading. Given previous sector and research practices, the suggested first steps require significant sector leadership and investment in Indigenous-led research

South East Australia Aboriginal Fire Forum: An Independent Research Report

The Southeast Australia Aboriginal Fire Forum was a landmark event, bringing together Aboriginal and non-indigenous peoples personally invested in expanding the use of cultural burning and supporting the authority of Aboriginal peoples in the management of bushfire in southeast Australia and across the Australian continent more generally. As the diverse presentations demonstrated, Aboriginal fire management practitioners in southeast Australia face distinct challenges and opportunities moving forward. This report identifies several key themes that emerged from across the forum: creating knowledge, sharing knowledge, everyone together, and making it genuine

B850: Representative Farm Budgets and Performance Indicators for Integrated Farming Practices in Maine

This report compares the relative profitability and sustainability of Maine farms integrating crops and livestock with comparable non-integrated or conventional farms. Potato and dairy systems coupled for only two years had greater profitability compared to conventional systems. Profitability increased in the short term in two ways. First, potato farms grew more of their primary cash crop. Second, dairy farms expanded cow numbers, increasing profitability assuming increasing returns to scale. Coupled systems integrated for more than ten years (long term) had more favorable profitability and sustainability measures than short-term couplers since greater manure-nutrient credits were taken for potatoes and silage corn. The picture improved even more if potato yields increased in the long term, as suggested by long-term rotation plot studies in Maine. Even if coupling is more profitable than nonintegrated systems, it still requires farms to be in close proximity and for farmers to have adequate working relationships.https://digitalcommons.library.umaine.edu/aes_bulletin/1004/thumbnail.jp

Students\u27 use of personal technology in the classroom: analyzing the perceptions of the digital generation

Faculty frequently express concerns about students’ personal use of information and communication technologies in today’s university classrooms. As a requirement of a graduate research methodology course in a university in Ontario, Canada, the authors conducted qualitative research to gain an in-depth understanding of students’ perceptions of this issue. Their findings reveal students’ complex considerations about the acceptability of technology use. Their analysis of the broader contexts of students’ use reveals that despite a technological revolution, university teaching practices have remained largely the same, resulting in ‘cultural lag’ within the classroom. While faculty are technically ‘in charge’, students wield power through course evaluations, surveillance technologies and Internet postings. Neoliberalism and the corporatisation of the university have engendered an ‘entrepreneurial student’ customer who sees education as a means to a career. Understanding students’ perceptions and their technological, social and political contexts offers insights into the tensions within today’s classrooms

Ionospheric electron number densities from CUTLASS dual-frequency velocity measurements using artificial backscatter over EISCAT

Using quasi-simultaneous line-of-sight velocity measurements at multiple frequencies from the Hankasalmi Cooperative UK Twin Auroral Sounding System (CUTLASS) on the Super Dual Auroral Radar Network (SuperDARN), we calculate electron number densities using a derivation outlined in Gillies et al. (2010, 2012). Backscatter targets were generated using the European Incoherent Scatter (EISCAT) ionospheric modification facility at Tromsø, Norway. We use two methods on two case studies. The first approach is to use the dual-frequency capability on CUTLASS and compare line-of-sight velocities between frequencies with a MHz or greater difference. The other method used the kHz frequency shifts automatically made by the SuperDARN radar during routine operations. Using ray tracing to obtain the approximate altitude of the backscatter, we demonstrate that for both methods, SuperDARN significantly overestimates Ne compared to those obtained from the EISCAT incoherent scatter radar over the same time period. The discrepancy between the Ne measurements of both radars may be largely due to SuperDARN sensitivity to backscatter produced by localized density irregularities which obscure the background levels

Baseline self reported functional health and vulnerability to post-traumatic stress disorder after combat deployment: prospective US military cohort study

Objective To determine if baseline functional health status, as measured by SF-36 (veterans), predicts new onset symptoms or diagnosis of post-traumatic stress disorder among deployed US military personnel with combat exposure

Polarimetric Properties of the Crab Pulsar between 1.4 and 8.4 GHz

New polarimetric observations of the Crab pulsar at frequencies between 1.4 and 8.4 GHz are presented. Additional pulse components discovered in earlier observations (Moffett & Hankins 1996, astro-ph/9604163) are found to have high levels of linear polarization, even at 8.4 GHz. No abrupt sweeps in position angle are found within pulse components; however, the position angle and rotational phase of the interpulse do change dramatically between 1.4 and 4.9 GHz. The multi-frequency profile morphology and polarization properties indicate a non-standard origin of the emission. Several emission geometries are discussed, but the one favored locates sites of emission both near the pulsar surface and in the outer magnetosphere.Comment: 20 pages, 7 postscript figures, uses aaspp4 Latex style. To appear in Volume 522 of The Astrophysical Journa

Mortality of Cranes (Gruidae) Associated with Powerlines over a Major Roost on the Platte River, Nebraska

Two 69-kilovolt powerlines spanning the Platte River in south central Nebraska are suspected to cause substantial mortality to sandhill cranes (Grus canadensis) and pose a threat to endangered whooping cranes (G. americana) that roost overnight on the river during spring and fall migrations. Most studies of crane collisions with powerlines in the region have focused on counts of carcasses away from night roosts on the river and none have accounted for potential biases in detecting carcasses. We found 61 carcasses of sandhill cranes below over-river segments of the two powerlines during 4 March to 7 April 2006 and 90 such carcasses between 5 March and 13 April 2007. In 2007 we estimated the number of carcasses undetected in our surveys due to removal by scavengers, loss to downstream flow, and observer oversight. We estimated between 165 and 219 sandhill cranes were killed by the two powerlines during spring 2007. These cnlculations exclude mortalities from individuals injured by powerline collisions and dying elsewhere, as well as those killed before or after our 5 March to 13 April survey period. We detected no evidence of mortality for whooping cranes during our surveys. Our results corroborate anecdotal evidence of signficant sandhill crane mortality each spring due to collisions with above-ground powerlines at this major night roost. Collisions by sandhill cranes will continue and collisions by Whooping cranes seem likely unless an effective means of averting birds from powerlines is implemented at this site