The Advancement of New Theology Using New Science: The Three Key Concepts of Thomas Torrance

The author begins with a selective outline of historical understandings of the concepts of space and time, in order to demonstrate their import for and engagement with theology. She then procedes to organize the three key concepts in Torrance\'s thought that are the most significant to the advancement of contemporary theology using insights from \"new science.\

Improving the external validity of clinical trials: the case of multiple chronic conditions

The U.S. Department of Health and Human Services vision and strategic framework on multiple chronic conditions (MCCs) incorporates recommendations designed to facilitate research that will improve our knowledge about interventions and systems that will benefit individuals with MCCs (or multimorbidity). The evidence base supporting the management of patients with MCCs will be built both through intervention trials specifically designed to address multimorbidity and identification of MCCs in participants across the clinical trial range. This article specifically focuses on issues relating to external validity with specific reference to trials involving patients with MCCs. The exclusion of such patients from clinical trials has been well documented. Randomized control trials (RCTs) are considered the “gold standard” of evidence, but may have drawbacks in relation to external validity, particularly in relation to multimorbidity. It may, therefore, be necessary to consider a broader range of research methods that can provide converging evidence on intervention effects to address MCCs. Approaches can also be taken to increase the usefulness of RCTs in general for providing evidence to inform multimorbidity management. Additional improvements to RCTs would include better reporting of inclusion and exclusion criteria and participant characteristics in relation to MCCs. New trials should be considered in terms of how they will add to the existing evidence base and should inform how interventions may work in different settings and patient groups. Research on treatments and interventions for patients with MCCs is badly needed. It is important that this research includes patient-centered measures and that generalizability issues be explicitly addressed.Journal of Comorbidity 2013;3(2)30–3

Reversibility of cell surface label rearrangement

Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is necessary to maintain as well as to induce rearrangements. With scanning electron microscopy, the rearrangement of concanavalin A (con A) and ricin binding sites on LA-9 cells has been followed by means of hemocyanin, a visual label. The removal of con A from its binding sites at the cell surface with alpha- methyl mannoside, and the return of these sites to their original distribution are also followed in this manner. There are labeling differences with con A and ricin. Under some conditions, however, the same rearrangements are seen with both lectins. The disappearance of labeled sites from areas of ruffling activity is a major feature of the rearrangements seen. Both this ruffling activity and the rearrangement of label are sensitive to cytochalasin B, and ruffling activity, perhaps along with other cytochalasin-sensitive structure, may play a role in the rearrangements of labeled sites

Expanding the Supply of High Quality Public Schools

Two levers that play critically important roles in determining how quickly and consistently successful schools and design models can be replicated. One is the degree of managerial responsibility, support, and control the organization chooses to exercise. The other is related to specificity of school design.This paper examines the school development landscape in the context of these levers, with examples of organizations that have chosen different paths with different tradeoffs and outcomes

Half a Million Older Californians Living Alone Unable to Make Ends Meet

Presents findings on the economic security of Californians age 65 and older, using the 2007 Elder Index, with a focus on those living alone. Analyzes data by race/ethnicity, gender, age, and county and compares income levels with the federal poverty line

On the Two-point Correlation of Potential Vorticity in Rotating and Stratified Turbulence

A framework is developed to describe the two-point statistics of potential vorticity in rotating and stratified turbulence as described by the Boussinesq equations. The Karman-Howarth equation for the dynamics of the two-point correlation function of potential vorticity reveals the possibility of inertial-range dynamics in certain regimes in the Rossby, Froude, Prandtl and Reynolds number parameters. For the case of large Rossby and Froude numbers, and for the case of quasi-geostrophic dynamics, a linear scaling law with 2/3 prefactor is derived for the third-order mixed correlation between potential vorticity and velocity, a result that is analogous to the Kolmogorov 4/5-law for the third-order velocity structure function in turbulence theory.Comment: 10 pages, to appear in Journal of Fluid Mechanics (2006

Evaluation of readability and accuracy of information leaflets in general practice for patients with asthma

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The Electrostatic Screening Length in Concentrated Electrolytes Increases with Concentration

According to classical electrolyte theories interactions in dilute (low ion density) electrolytes decay exponentially with distance, with the Debye screening length the characteristic length-scale. This decay length decreases monotonically with increasing ion concentration, due to effective screening of charges over short distances. Thus within the Debye model no long-range forces are expected in concentrated electrolytes. Here we reveal, using experimental detection of the interaction between two planar charged surfaces across a wide range of electrolytes, that beyond the dilute (Debye-Huuckel) regime the screening length increases with increasing concentration. The screening lengths for all electrolytes studied - including aqueous NaCl solutions, ionic liquids diluted with propylene carbonate, and pure ionic liquids - collapse onto a single curve when scaled by the dielectric constant. This non-monotonic variation of the screening length with concentration, and its generality across ionic liquids and aqueous salt solutions, demonstrates an important characteristic of concentrated electrolytes of substantial relevance from biology to energy storage.Comment: This document is the unedited authors' version of a Submitted Work that was subsequently accepted for publication in the Journal of Physical Chemistry Letters, copyright American Chemical Society, after peer review. To access the final edited and published work see http://pubsdc3.acs.org/articlesonrequest/AOR-EW6FuIC6wIh6D9qqEeH

Developing and Implementing Self-Direction Programs and Policies: A Handbook

Provides a guide to designing, implementing, and evaluating service delivery models that allow public program participants to manage their own care services and supports. Outlines elements of employer and budget authorities, enrollment, and counseling