4,385 research outputs found
Facilitating Access to the Role Models of Women in STEM: W-STEM Mobile App
W-STEM is a research project funded by the European Union
through the Erasmus+ program in order to develop concrete actions to modernise
the government, management and operation of higher education institutions
in Latin America to improve women’s access to STEM programs. Among
the main objectives of the project, there is the development of a mobile app to be
used in attraction campaigns conducted by the Latin American higher education
institutions involved in the project. Specifically, the app aims to facilitate access
to the role models of women in areas related to science, technology, engineering
and mathematics. The main content inside the app will be a set of video
interviews with women from different ages, cultural backgrounds, profiles,
sharing their experiences about their careers, occupation and future plans. This
work aims to describe the prototype of the mobile app and the exploratory study
conducted with a group of students from secondary education to know their
perceptions and opinions about the proposed app and the video interviews
Sympathetic and swap cooling of trapped ions by cold atoms in a MOT
A mixed system of cooled and trapped, ions and atoms, paves the way for ion
assisted cold chemistry and novel many body studies. Due to the different
individual trapping mechanisms, trapped atoms are significantly colder than
trapped ions, therefore in the combined system, the strong binary ionatom
interaction results in heat flow from ions to atoms. Conversely, trapped ions
can also get collisionally heated by the cold atoms, making the resulting
equilibrium between ions and atoms intriguing. Here we experimentally
demonstrate, Rubidium ions (Rb) cool in contact with magneto-optically
trapped (MOT) Rb atoms, contrary to the general expectation of ion heating for
equal ion and atom masses. The cooling mechanism is explained theoretically and
substantiated with numerical simulations. The importance of resonant charge
exchange (RCx) collisions, which allows swap cooling of ions with atoms,
wherein a single glancing collision event brings a fast ion to rest, is
discussed.Comment: 10 pages, 3 figure
The New Political Economy of EU State Aid Policy
Despite its importance and singularity, the EU’s state aid policy has attracted less scholarly attention than other elements of EU competition policy. Introducing the themes addressed by the special issue, this article briefly reviews the development of EU policy and highlights why the control of state aid matters. The Commission’s response to the current economic crisis notably in banking and the car industry is a key concern, but the interests of the special issue go far beyond. They include: the role of the European Commission in the development of EU policy, the politics of state aid, and a clash between models of capitalism. The special issue also examines the impact of EU policy. It investigates how EU state aid decisions affect not only industrial policy at the national level (and therefore at the EU level), but the welfare state and territorial relations within federal member states, the external implications of EU action and the strategies pursued by the Commission to limit any potential disadvantage to European firms, and the conflict between the EU’s expanding legal order and national
A Method of Drusen Measurement Based on the Geometry of Fundus Reflectance
BACKGROUND: The hallmarks of age-related macular degeneration, the leading cause of blindness in the developed world, are the subretinal deposits known as drusen. Drusen identification and measurement play a key role in clinical studies of this disease. Current manual methods of drusen measurement are laborious and subjective. Our purpose was to expedite clinical research with an accurate, reliable digital method. METHODS: An interactive semi-automated procedure was developed to level the macular background reflectance for the purpose of morphometric analysis of drusen. 12 color fundus photographs of patients with age-related macular degeneration and drusen were analyzed. After digitizing the photographs, the underlying background pattern in the green channel was leveled by an algorithm based on the elliptically concentric geometry of the reflectance in the normal macula: the gray scale values of all structures within defined elliptical boundaries were raised sequentially until a uniform background was obtained. Segmentation of drusen and area measurements in the central and middle subfields (1000 μm and 3000 μm diameters) were performed by uniform thresholds. Two observers using this interactive semi-automated software measured each image digitally. The mean digital measurements were compared to independent stereo fundus gradings by two expert graders (stereo Grader 1 estimated the drusen percentage in each of the 24 regions as falling into one of four standard broad ranges; stereo Grader 2 estimated drusen percentages in 1% to 5% intervals). RESULTS: The mean digital area measurements had a median standard deviation of 1.9%. The mean digital area measurements agreed with stereo Grader 1 in 22/24 cases. The 95% limits of agreement between the mean digital area measurements and the more precise stereo gradings of Grader 2 were -6.4 % to +6.8 % in the central subfield and -6.0 % to +4.5 % in the middle subfield. The mean absolute differences between the digital and stereo gradings 2 were 2.8 +/- 3.4% in the central subfield and 2.2 +/- 2.7% in the middle subfield. CONCLUSIONS: Semi-automated, supervised drusen measurements may be done reproducibly and accurately with adaptations of commercial software. This technique for macular image analysis has potential for use in clinical research
The impact of provider surgical volumes on survival in children with primary tumors of the central nervous system—a population-based study
Category label and response location shifts in category learning
The category shift literature suggests that rule-based classification, an important form of explicit learning, is mediated by two separate learned associations: a stimulus-to-label association that associates stimuli and category labels, and a label-to-response association that associates category labels and responses. Three experiments investigate whether information–integration classification, an important form of implicit learning, is also mediated by two separate learned associations. Participants were trained on a rule-based or an information–integration categorization task and then the association between stimulus and category label, or between category label and response location was altered. For rule-based categories, and in line with previous research, breaking the association between stimulus and category label caused more interference than breaking the association between category label and response location. However, no differences in recovery rate emerged. For information–integration categories, breaking the association between stimulus and category label caused more interference and led to greater recovery than breaking the association between category label and response location. These results provide evidence that information–integration category learning is mediated by separate stimulus-to-label and label-to-response associations. Implications for the neurobiological basis of these two learned associations are discussed
Electronic measurement and control of spin transport in Silicon
The electron spin lifetime and diffusion length are transport parameters that
define the scale of coherence in spintronic devices and circuits. Since these
parameters are many orders of magnitude larger in semiconductors than in
metals, semiconductors could be the most suitable for spintronics. Thus far,
spin transport has only been measured in direct-bandgap semiconductors or in
combination with magnetic semiconductors, excluding a wide range of
non-magnetic semiconductors with indirect bandgaps. Most notable in this group
is silicon (Si), which (in addition to its market entrenchment in electronics)
has long been predicted a superior semiconductor for spintronics with enhanced
lifetime and diffusion length due to low spin-orbit scattering and lattice
inversion symmetry. Despite its exciting promise, a demonstration of coherent
spin transport in Si has remained elusive, because most experiments focused on
magnetoresistive devices; these methods fail because of universal impedance
mismatch obstacles, and are obscured by Lorentz magnetoresistance and Hall
effects. Here we demonstrate conduction band spin transport across 10 microns
undoped Si, by using spin-dependent ballistic hot-electron filtering through
ferromagnetic thin films for both spin-injection and detection. Not based on
magnetoresistance, the hot electron spin-injection and detection avoids
impedance mismatch issues and prevents interference from parasitic effects. The
clean collector current thus shows independent magnetic and electrical control
of spin precession and confirms spin coherent drift in the conduction band of
silicon.Comment: Single PDF file with 4 Figure
Multimorbidity in bipolar disorder and under-treatment of cardiovascular disease: a cross sectional study
Background: Individuals with serious mental disorders experience poor physical health, especially increased rates of cardiometabolic morbidity and premature morbidity. Recent evidence suggests that individuals with schizophrenia have numerous comorbid physical conditions which may be under-recorded and under-treated but to date very few studies have explored this issue for bipolar disorder.
Methods:We conducted a cross-sectional analysis of a dataset of 1,751,841 registered patients within 314 primary-care practices in Scotland, U.K. Bipolar disorder was identified using Read Codes recorded within electronic medical records. Data on 32 common chronic physical conditions were also assessed. Potential prescribing inequalities were evaluated by analyzing prescribing data for coronary heart disease (CHD) and hypertension.
Results: Compared to controls, individuals with bipolar disorder were significantly less likely to have no recorded physical conditions (OR 0.59, 95% CI 0.54-0.63) and significantly more likely to have one physical condition (OR 1.27, 95% CI 1.16-1.39), two physical conditions (OR 1.45, 95% CI 1.30-1.62) and three or more physical conditions (OR 1.44, 95% CI 1.30-1.64). People with bipolar disorder also had higher rates of thyroid disorders, chronic kidney disease, chronic pain, chronic obstructive airways disease and diabetes but, surprisingly, lower recorded rates of hypertension and atrial fibrillation. People with bipolar disorder and comorbid CHD or hypertension were significantly more likely to be prescribed no antihypertensive or cholesterol-lowering medications compared to controls, and bipolar individuals with CHD or hypertension were significantly less likely to be on 2 or more antihypertensive agents.
Conclusions: Individuals with bipolar disorder are similar to individuals with schizophrenia in having a wide range of comorbid and multiple physical health conditions. They are also less likely than controls to have a primary-care record of cardiovascular conditions such as hypertension and atrial fibrillation. Those with a recorded diagnosis of CHD or hypertension were less likely to be treated with cardiovascular medications and were treated less intensively. This study highlights the high physical healthcare needs of people with bipolar disorder, and provides evidence for a systematic under-recognition and under-treatment of cardiovascular disease in this group
Evaluation of test statistics in split-mouth clinical trials
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65787/1/j.1600-0765.1988.tb01616.x.pd
- …