Rural workers have less access to paid sick days

This brief, using data from the 2008 National Study of the Changing Workforce (NSCW) survey, analyzes paid sick time rates of workers by place and type of work. Paid sick days provide job protection to workers and a steady paycheck when they need to care for themselves or family members. Paid sick days also help workers with more limited resources who cannot otherwise afford to take a day off. Authors Kristin Smith and Andrew Schaefer report that a greater proportion of rural workers than urban workers (both suburban and central-city) lack access to at least five paid sick days per year. Their analysis suggests that where one works matters, both geographically and by sector, and the quality of the job also matters. The rural disadvantage is particularly pronounced among rural private-sector workers and part-time workers, but even rural full-time workers have less access to paid sick days than their urban counterparts

Who cares for the sick kids? parents’ access to paid time to care for a sick child

This brief analyzes employed parents’ access to five or more paid sick days annually to care for a sick child in 2008. Using data from the 2008 National Study of the Changing Workforce collected by the Families and Work Institute (the most recent data available in the series), authors Kristin Smith and Andrew Schaefer analyze differences in access between employed mothers and fathers by demographic and work-related characteristics. They report that, in 2008, more than one-half—52 percent—of employed parents lacked access to at least five paid sick days to care for a sick child, and lower-earning parents had the least access. Although employed mothers and fathers have similar access to paid sick days to care for their sick children, mothers more often miss work to care for a sick child. Employed parents with paid sick days to care for a sick child are 1.9 times more likely to be very satisfied with their job than those without this access

Families Continue to Rely on Wives As Breadwinners Post-Recession

This brief uses data from the 2013 Annual Social and Economic Supplement to the Current Population Survey to examine how President Obama’s proposed expanded eligibility and higher credit values might affect tax filers in both rural and urban America. Authors Jessica Carson and Marybeth Mattingly report that proposed changes to the earned income tax credit (EITC) will increase the share of workers without a qualifying child eligible for the EITC equally in rural and urban places, although rural residents are more likely to be eligible under both current and proposed policies. The average increase in the credit is $476, more than double the average current credit, and would be similar for married and single filers without qualifying children in both rural and urban places. The number of unmarried filers who would become eligible for the credit is significantly higher than the number of married filers, in both urban and rural places

Prospects for World Peace and Security

The thesis assesses the prospects for global conflict or security using both traditionalist and modernist theory of international relations

An update on stress, fatigue and wellbeing: implications for naval personnel

The aim of the present article is to provide an update on recent research on stress, fatigue and wellbeing and discuss the implications for naval personnel. There is now considerable information on these topics in onshore civilian populations and some research on seafarers and other military personnel. This generic information can now be used to address these issues in naval personnel. In order to do this there is a need to consider specific naval contexts and to collect data to confirm the applicability of established methods and models to the navy

Characterization of a temperature-sensitive DNA ligase from Escherichia coli

DNA ligases are essential enzymes in cells due to their ability to join DNA strand breaks formed during DNA replication. Several temperature-sensitive mutant strains of Escherichia coli, including strain GR501, have been described which can be complemented by functional DNA ligases. Here, it is shown that the ligA251 mutation in E. coli GR501 strain is a cytosine to thymine transition at base 43, which results in a substitution of leucine by phenylalanine at residue 15. The protein product of this gene (LigA251) is accumulated to a similar level at permissive and non-permissive temperatures. Compared to wild-type LigA, at 20 °C purified LigA251 has 20-fold lower ligation activity in vitro, and its activity is reduced further at 42 °C, resulting in 60-fold lower ligation activity than wild-type LigA. It is proposed that the mutation in LigA251 affects the structure of the N-terminal region of LigA. The resulting decrease in DNA ligase activity at the non-permissive temperature is likely to occur as the result of a conformational change that reduces the rate of adenylation of the ligase

A preliminary review of fatigue among rail staff

Background: Fatigue is a severe problem in the rail industry, which may jeopardize train crew's health and safety. Nonetheless, a preliminary review of all empirical evidence for train crew fatigue is still lacking. The aim of the present paper is, therefore, to provide a preliminary description of occupational fatigue in the rail industry. This paper reviews the literature with the research question examining the risk factors associated with train crew fatigue, covering both papers published in refereed journals and reports from trade organizations and regulators. It assesses the progress of research on railway fatigue, including research on the main risk factors for railway fatigue, the association between fatigue and railway incidents, and how to better manage fatigue in the railway industry. Methods: Systematic searches were performed in both science and industry databases. The searches considered studies published before August 2017. The main exclusion criterion was fatigue not being directly measured through subjective or objective methods. Results: A total of 31 studies were included in the main review. The causes of fatigue included long working hours, heavy workload, early morning or night shifts, and insufficient sleep. Poor working environment, particular job roles, and individual differences also contributed to fatigue. Conclusion: Fatigue in the rail industry includes most of the features of occupational fatigue, and it is also subject to industry-specific factors. The effect of fatigue on well-being and the fatigued population in the railway industry are still not clear. Future studies can consider associations between occupational risk factors and perceived fatigue by examining the prevalence of fatigue and identifying the potential risk factors in staff within the railway industry

Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype.

Kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Recent evidence indicates that kisspeptin is also important for body weight and metabolism, as whole-body Kiss1r KO mice, developed with gene trap technology, display obesity and reduced metabolism. Kiss1r is expressed in brain and multiple peripheral tissues, but it is unknown which is responsible for the metabolic phenotype. Here, we sought to confirm that 1) the metabolic phenotype of the gene trap Kiss1r KOs is due to disruption of kisspeptin signaling and not off-target effects of viral mutagenesis, and 2) the Kiss1r flox line is suitable for creating conditional KOs to study the metabolic phenotype. We used Cre/lox technology (Zp3-Cre/Kiss1r flox) to develop a new global Kiss1r KO ("Kiss1r gKO") to compare with the original gene trap KO phenotype. We confirmed that deleting exon 2 of Kiss1r from the entire body induces hypogonadism in both sexes. Moreover, global deletion of Kiss1r induced obesity in females, but not males, along with increased adiposity and impaired glucose tolerance, similar to the gene trap Kiss1r KOs. Likewise, Kiss1r gKO females had decreased VO2 and VCO2, likely underlying their obesity. These findings support that our previous results in gene trap Kiss1r KOs are due to disrupted kisspeptin signaling, and further highlight a role for Kiss1r signaling in energy expenditure and metabolism besides controlling reproduction. Moreover, given Kiss1r expression in multiple cell-types, our findings indicate that the Kiss1r flox line is viable for future investigations to isolate specific target cells of kisspeptin's metabolic effects