The Value of Black Monukka, Perlette, Ruby Seedless and Sultanina as parents for breeding Raisin Grapes

The seedless grape cultivars Black Monukka, Perlette, Ruby Seedless and Sultanina were used as pollen parents and hybridized with two muscat flavoured and four neutral flavoured cultivars and selections in an effort to breed seedless table grapes. The progeny of some of these crosses were also evaluated for raisin quality during the 1983/84 season. Ten seedless selections and 21 selections possessing trace seeds (1-2 mm) obtained a quality rating comparable to that of Merbein Seedless, Fiesta, Perlette and Sultanina raisins. Perlette produced four times as many seedlings with satisfactory raisin quality as all the other crosses combined. The cross CG 1272 X Sultanina produced five promising white currant types. Selection CG 1272 appears to be a valuable parent for breeding improved currant types

Solo Voice Detection Via Optimal Cancellation

Automatically identifying sections of solo voices or instruments within a large corpus of music recordings would be useful, for example, to construct a library of isolated instruments to train signal models. We consider several ways to identify these sections, including a baseline classifier trained on conventional speech features. Our best results, achieving frame level precision and recall of around 70%, come from an approach that attempts to track the local periodicity of an assumed solo musical voice, then classifies the segment as a genuine solo or not on the basis of what proportion of the energy can be canceled by a comb filter constructed to remove just that periodicity

Predictors of psychological adjustment after bereavement.

Background: The impact of spousal bereavement on mental health varies among the widowed. More information is needed on factors influencing bereavement outcome. Method: We conducted a cross-sectional study on a sample of 216 widowed individuals. Initial non-response was high, with only 8% of all approached persons participating in the study. The influence of demographic and psychosocial predictors on four general outcome measures (depression, anxiety, somatization, and quality of life) and one loss-related outcome (complicated grief) was studied by means of backward linear regression analysis. Further analyses were performed to explore the possibility of a buffer effect. Results: Depressive symptomatology was best predicted by: age, duration of widowhood, perceived non-supportiveness, physical disorders, and mastery. The other outcome measures were predicted by the same predictors supplemented by gender and education. Mastery interacted with the number of physical disorders while perceived social support interacted with duration of widowhood and age. Conclusions: Enhancement of mastery should probably be one of the components of effective support for widowed individuals most vulnerable to psychiatric complications. The widowed could furthermore benefit from social support. Obviously, these suggestions need to be further examined in longitudinal research with more representative samples. © 2006 International Psychogeriatric Association

Chiral Lattice Gauge Theories Via Mirror-Fermion Decoupling: A Mission (im)Possible?

This is a review of the status and outstanding issues in attempts to construct chiral lattice gauge theories by decoupling the mirror fermions from a vectorlike theory. In the first half, we explain why studying nonperturbative chiral gauge dynamics may be of interest, enumerate the problems that a lattice formulation of chiral gauge theories must overcome, and briefly review our current knowledge. We then discuss the motivation and idea of mirror-fermion decoupling and illustrate the desired features of the decoupling dynamics by a simple solvable toy model. The role of exact chiral symmetries and matching of 't Hooft anomalies on the lattice is also explained. The second, more technical, half of the article is devoted to a discussion of the known and unknown features of mirror-decoupling dynamics formulated with Ginsparg-Wilson fermions. We end by pointing out possible directions for future studies.Comment: 53 pp; 6 figs; added table of contents, references, fixed typo

Plaque quantitiation through protein measurement

PKThis study was undertaken to establish whether the quantitation of dental plaque protein by a dye-binding method (Coomassie G-250) may be used as an index of the amount of dental plaque sampled. Ten sites were sampled in 34 children on 5 occasions at 4 month intervals. The mean protein concentration in 1391 plaque samples was 6.9 +/- 4.1 micrograms (micrograms) (mean +/- standard deviation). A three-way analysis of variance showed that the plaque protein concentration was similar at the different sampling sites in the same child (p = 0.14), but statistically significant differences were observed with respect to time of sampling (F = 36.24; p = 0.0001) and individual sampled (F = 5.69; p = 0.0001). These observations indicate that plaque bacterial counts may be expressed as units of protein concentration and this method may be useful to relate the number of viable bacteria to an estimate of the amount of plaque collected. This ratio allows standardisation for any variation in the amount of plaque collected

Improvement and Taste Symmetry Breaking for Staggered Quarks

We compare several improved actions for staggered quarks. We study the effect of improvement on the taste changing interactions by calculating the splitting in the pion spectrum. We investigate the effect of the improvement on some topological properties.Comment: 3 pages, 3 figures, Lattice 2003 proceeding

Lattice Gauge Theories and the Heisenberg Antiferromagnetic Chain

We study the strongly coupled 2-flavor lattice Schwinger model and the SU(2)-color QCD_2. The strong coupling limit, even with its inherent nonuniversality, makes accurate predictions of the spectrum of the continuum models and provides an intuitive picture of the gauge theory vacuum. The massive excitations of the gauge model are computable in terms of spin-spin correlators of the quantum Heisenberg antiferromagnetic spin-1/2 chain.Comment: Proceedings LATTICE99 (spin models), 3 page

A phase II study of paclitaxel in heavily pretreated patients with small-cell lung cancer.

The purpose of the study was to delineate the efficacy and toxicity of paclitaxel (Taxol, Bristol Myers Squibb) in the treatment of drug resistant small-cell lung cancer (SCLC). Patients with SCLC relapsing within 3 months of cytotoxic therapy received paclitaxel 175 mg m(-2) intravenously over 3 h every 3 weeks. The dose of paclitaxel was adjusted to the toxicity encountered in the previous cycle. Of 24 patients entered into the study, 24 and 21 were assessable for response and toxicity respectively. There were two early deaths and two toxic deaths. No complete and seven partial responses (29%) (95%CI 12-51%) were observed and five patients had disease stabilization. The median survival (n = 21) was 100 days. Life-threatening toxicity occurred in four patients; in others (non)-haematological toxicity was manageable. Paclitaxel is active in drug-resistant SCLC. Further investigation in combination with other active agents in this poor prognosis group is appropriate

Metallic properties of magnesium point contacts

We present an experimental and theoretical study of the conductance and stability of Mg atomic-sized contacts. Using Mechanically Controllable Break Junctions (MCBJ), we have observed that the room temperature conductance histograms exhibit a series of peaks, which suggests the existence of a shell effect. Its periodicity, however, cannot be simply explained in terms of either an atomic or electronic shell effect. We have also found that at room temperature, contacts of the diameter of a single atom are absent. A possible interpretation could be the occurrence of a metal-to-insulator transition as the contact radius is reduced, in analogy with what it is known in the context of Mg clusters. However, our first principle calculations show that while an infinite linear chain can be insulating, Mg wires with larger atomic coordinations, as in realistic atomic contacts, are alwaysmetallic. Finally, at liquid helium temperature our measurements show that the conductance histogram is dominated by a pronounced peak at the quantum of conductance. This is in good agreement with our calculations based on a tight-binding model that indicate that the conductance of a Mg one-atom contact is dominated by a single fully open conduction channel.Comment: 14 pages, 5 figure

Phase I study of high-dose epirubicin and vinorelbine in previously untreated non-small-cell lung cancer stage IIIB-IV.

The aim of the study was to determine the maximum tolerated dose (MTD) for the combination of high-dose epirubicin and vinorelbine in chemotherapy-naive patients with inoperable non-small-cell lung cancer (NSCLC). Twenty-one patients with stage IIIB and IV NSCLC were treated in a single-centre study with escalating doses of epirubicin and vinorelbine given on an outpatient basis. The first dose level comprised epirubicin 100 mg m-2 on day 1 and vinorelbine 20 mg m-2 (days 1 and 8) given intravenously every 3 weeks. Escalating doses for epirubicin and vinorelbine were respectively 120 (day 1) and 20 (days 1 and 8), 120 (day 1) and 25 (days 1 and 8) and 135 (day 1) and 25 (days 1 and 8) mg m-2. Inclusion criteria were age < or = 75 years, ECOG performance score < or = 2 and normal renal, hepatic and bone marrow functions. Dose-limiting toxicities were thrombocytopenia grade II and neutropenia grade III on day 8, febrile neutropenia, and neutropenia lasting > 7 days. No dose-limiting toxicity (DLT) was observed at the first dose level; at the 135/25 mg m-2 dose level three out of six patients had a DLT which was considered as unacceptable. The only non-haematological toxicity reaching grade III was nausea/vomiting. One patient showed cardiac toxicity. No neurotoxicity and no treatment-related deaths were seen. The maximum tolerated dose of epirubicin and vinorelbine is 135 mg m-2 (day 1) and 25 mg m-2 (days 1 and 8) respectively, causing mainly haematological toxicity. The recommended dose of epirubicin and vinorelbine for phase II studies is found to be 120 mg m-2 and 20 mg m-2 respectively