Neuronal avalanches of a self-organized neural network with active-neuron-dominant structure

Neuronal avalanche is a spontaneous neuronal activity which obeys a power-law distribution of population event sizes with an exponent of -3/2. It has been observed in the superficial layers of cortex both \emph{in vivo} and \emph{in vitro}. In this paper we analyze the information transmission of a novel self-organized neural network with active-neuron-dominant structure. Neuronal avalanches can be observed in this network with appropriate input intensity. We find that the process of network learning via spike-timing dependent plasticity dramatically increases the complexity of network structure, which is finally self-organized to be active-neuron-dominant connectivity. Both the entropy of activity patterns and the complexity of their resulting post-synaptic inputs are maximized when the network dynamics are propagated as neuronal avalanches. This emergent topology is beneficial for information transmission with high efficiency and also could be responsible for the large information capacity of this network compared with alternative archetypal networks with different neural connectivity.Comment: Non-final version submitted to Chao

Orbiter/launch system

The system includes reusable turbojet propelled booster vehicles releasably connected to a reusable rocket powered orbit vehicle. The coupled orbiter-booster combination takes off horizontally and ascends to staging altitude and speed under booster power with both orbiter and booster wings providing lift. After staging, the booster vehicles fly back to Earth for horizontal landing and the orbiter vehicle continues ascending to orbit

Aerodynamic tests and analysis of a turbojet-boosted launch vehicle concept (spacejet) over a Mach number range of 1.50 to 2.86

Results from analytical and experimental studies of the aerodynamic characteristics of a turbojet-boosted launch vehicle concept through a Mach number range of 1.50 to 2.86 are presented. The vehicle consists of a winged orbiter utilizing an area-ruled axisymmetric body and two winged turbojet boosters mounted underneath the orbiter wing. Drag characteristics near zero lift were of prime interest. Force measurements and flow visualization techniques were employed. Estimates from wave drag theory, supersonic lifting surface theory, and impact theory are compared with data and indicate the ability of these theories to adequately predict the aerodynamic characteristics of the vehicle. Despite the existence of multiple wings and bodies in close proximity to each other, no large scale effects of boundary layer separation on drag or lift could be discerned. Total drag levels were, however, sensitive to booster locations

Estimating the distribution of dynamic invariants: illustrated with an application to human photo-plethysmographic time series

Dynamic invariants are often estimated from experimental time series with the aim of differentiating between different physical states in the underlying system. The most popular schemes for estimating dynamic invariants are capable of estimating confidence intervals, however, such confidence intervals do not reflect variability in the underlying dynamics. We propose a surrogate based method to estimate the expected distribution of values under the null hypothesis that the underlying deterministic dynamics are stationary. We demonstrate the application of this method by considering four recordings of human pulse waveforms in differing physiological states and show that correlation dimension and entropy are insufficient to differentiate between these states. In contrast, algorithmic complexity can clearly differentiate between all four rhythms

Time transfer between the Goddard Optical Research Facility and the U.S. Naval Observatory using 100 picosecond laser pulses

A horizontal two-way time comparison link in air between the University of Maryland laser ranging and time transfer equipment at the Goddard Optical Research Facility (GORF) 1.2 m telescope and the Time Services Division of the U.S. Naval Observatory (USNO) was established. Flat mirrors of 25 cm and 30 cm diameter respectively were placed on top of the Washington Cathedral and on a water tower at the Beltsville Agricultural Research Center. Two optical corner reflectors at the USNO reflect the laser pulses back to the GORF. Light pulses of 100 ps duration and an energy of several hundred microjoules are sent at the rate of 10 pulses per second. The detection at the USNO is by means of an RCA C30902E avalanche photodiode and the timing is accomplished by an HP 5370A computing counter and an HP 1000 computer with respect to a 10 pps pulse train from the Master Clock

Helicobacter pylori interstrain restriction-modification diversity prevents genome subversion by chromosomal DNA from competing strains

Helicobacter pylori, bacteria that colonize the human gastric mucosa, possess a large number of genes for restriction‐modification (R‐M) systems, and essentially, every strain possesses a unique complement of functional and partial R‐M systems. Nearly half of the H.pylori strains studied possess an active type IIs R‐M system, HpyII, with the recognition sequence GAAGA. Recombination between direct repeats that flank the R‐M cassette allows for its deletion whereas strains lacking hpyIIRM can acquire this cassette through natural transformation. We asked whether strains lacking HpyII R‐M activity can acquire an active hpyIIRM cassette [containing a 1.4 kb kanamycin resistance (aphA) marker], whether such acquisition is DNase sensitive or resistant and whether restriction barriers limit acquisition of chromosomal DNA. Our results indicate that natural transformation and conjugation‐like mechanisms may contribute to the transfer of large (4.8 kb) insertions of chromosomal DNA between H.pylori strains, that inactive or partial R‐M systems can be reactivated upon recombination with a functional allele, consistent with their being contingency genes, and that H.pylori R‐M diversity limits acquisition of chromosomal DNA fragments of ≥1 kb

QSO's from Galaxy Collisions with Naked Black Holes

In the now well established conventional view (see Rees [1] and references therein), quasi-stellar objects (QSOs) and related active galactic nuclei (AGN) phenomena are explained as the result of accretion of plasma onto giant black holes which are postulated to form via gravitational collapse of the high density regions in the centers of massive host galaxies. This model is supported by a wide variety of indirect evidence and seems quite likely to apply at least to some observed AGN phenomena. However, one surprising set of new Hubble Space Telescope (HST) observations [2-4] directly challenges the conventional model, and the well known evolution of the QSO population raises some additional, though not widely recognized, difficulties. We propose here an alternative possibility: the Universe contains a substantial independent population of super-massive black holes, and QSO's are a phenomenon that occurs due to their collisions with galaxies or gas clouds in the intergalactic medium (IGM). This hypothesis would naturally explain why the QSO population declines very rapidly towards low redshift, as well as the new HST data.Comment: plain TeX file, no figures, submitted to Natur

Capillary electrophoresis-fluorescence line narrowing system (CE-FLNS) for on-line structural characterization

Capillary electrophoresis (CE) is interfaced with low temperature fluorescenceline-narrowing (FLN) spectroscopy for on-line structural characterization of separated molecular analytes