43 research outputs found

    Ultrareliable, fault-tolerant control systems: A conceptual description

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    An Ultrareliable, Fault-Tolerant, Control-System (UFTCS) concept is described using a systems design philosophy which allows development of system structures containing virtually no common elements. Common elements limit achievable system reliability and can cause catastrophic loss of fault-tolerant system function. The UFTCS concept provides the means for removing common system elements by permitting the elements of the system to operate as independent, uncoupled entities. Multiple versions of the application program are run on dissimilar hardware. Fault tolerance is achieved through the use of static redundancy management

    The pH Dependence of the Spectral and Anion Binding Properties of Iron Containing Superoxide Dismutase from E. Coli B: An Explanation for the Azide Inhibition of Dismutase Activity

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    Examination of the optical and EPR properties of the ferric form of the iron containing superoxide dismutase from E. coli B, at pH values ranging from 4.5 to 10.9, has revealed two reversible structural transitions affecting the Fe 3+ ion. The apparent p K a . values of these transitions are 5.1±0.3 and 9.0±0.3. The binding of azide has been studied over the pH range 4.5 to 10.7; the affinity of the Fe 3+ for N 3 − is independent of pH from 4.5 to ∼ 7.5, after which the dissociation constant decreased by a factor of 10 per unit increase in pH. The apparent p K a . which affects N 3 − binding to the iron is 8.6±0.2. The association of N 3 − with the iron has been examined using the temperature‐jump method at pH 7.4 and 9.3. The kinetics of ligand association were shown to conform to the minimal mechanism: K 1 was found to be essentially unaffected by pH whereas K 2 was much lower at pH 9.3 than at 7.4. The value of K 1 at pH 7.4 (100 M −1 ) corresponds very closely to that obtained for the inhibition constant of azide, 10 mM. 12 A scheme is presented in which N 3 − inhibits the iron containing dismutase by competing with O 2 − for an anion binding site near, but not on the Fe 3+ .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/101818/1/198100014_ftp.pd

    The Effect of Pressure on Solid State Spectra

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    110 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1958.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD

    Uniform-drop-generation method for calibrating spray analyzer : progress report no. 1

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    http://deepblue.lib.umich.edu/bitstream/2027.42/7655/5/bad2127.0001.001.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/7655/4/bad2127.0001.001.tx

    Characterization of an orthorhombic crystal form of iron-containing superoxide dismutase from Escherichia coli B

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    Crystals suitable for X-ray diffraction studies of iron-containing superoxide dismutase from Escherichia coli have been grown using ammonium sulfate as the precipitant. The space group is P212121 with a = 81.8 A, B = 75.2 A, C = 71.3 A. A dimer of Mr = 40,000 occupies the asymmetric unit.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22548/1/0000093.pd

    Evaluation of proposed test methods for air cleaners : interim technical report

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    http://deepblue.lib.umich.edu/bitstream/2027.42/4001/5/bac0102.0002.001.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/4001/4/bac0102.0002.001.tx

    Electronic drop analyzer : final report

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    http://deepblue.lib.umich.edu/bitstream/2027.42/8429/5/bad5731.0001.001.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/8429/4/bad5731.0001.001.tx
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