The reproducibility within the laboratory of findings in a three month toxicity study in the rat

A three month rat toxicity study was conducted twice with the same compound in the same laboratory. The studies were conducted according to internationally recognized guidelines for subchronic toxicity studies and followed essentially identical protocols (a control group and three dose groups, 10 rats/sex/ group). The compound was administered subcutaneously once daily for three months. Body weight and food and water intake were measured once weekly. Blood samples for hematology and blood chemistry were taken during the week before termination of dosing. Body weight gain and food and water intake were increased in both studies. For great many hematological and blood chemical parameters there was a dosedependent statistically significant increase or decrease in one or both sexes. Some changes attained only the level of significance in one study whereas there was a tendency of a similar change in the other study. Only a few deviations (no or opposit change in one study) were seen between the two studies. Altogether there seemed to be a good correspondance between the findings in the two studies and the variations seen would probably not influence the safety evaluation made from any of the studies

HIV, et hus og et jubilæum

AIDS har ikke tidligere været udstillet på Steno Museet. Et nyt afsnit med genstande fra både Danmark og Afrika aktualiserer museets afsnit om epidemiske sygdomme

Hjertekunst

Et hjerte kan gå i tusinde stykker

Skou og forskerlivet

Science Museerne har fået 3 millioner kr. til en udstilling om forskerlivet og nobelpristageren Jens Christian Skou. Den skal åbne, når han fylder 100 år i 2018

Det uperfekte barn

Steno Museet har fået knap 600.000 kroner til udstillingen og bogen Det uperfekte barn. Udstillingen åbner i slutningen af september

Sundhedsvæsenet. Hvad skal der ske med det?

Den nye udstilling Gentests og tandbørster åbnede 21. maj med et vælgermøde ledet af journalist Adam Holm med politikere fra de fleste partier

Science Museerne vinder museumspris

Den internationale organisation af universitetsmuseer, UMAC, uddeler hvert år en pris til et universitetsmuseum for initiativer, som udmærker sig ved at være “excellente” og “innovative”. I år gik den til Science Museerne