Hidradenitis Suppurativa Online Documents Readability: An Analysis Including 23 European Languages

Tomasz Skrzypczak,1 Anna Skrzypczak,2 Jacek C Szepietowski1 1Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland; 2Department of Periodontology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Jacek C Szepietowski, Chair of the Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chalubinskiego, Wroclaw, 1 50-368, Poland, Email [email protected]: Hidradenitis suppurativa (HS) is a complex disease with the vast burden to patients. The aim of the study was to evaluate readability of online electronic materials dedicated to HS.Patients and Methods: The terms “hidradenitis suppurativa” and “acne inversa” translated into 23 official European Union languages were searched with Google. For each language, first 50 results were assessed for suitability. Included materials were focused on patient’s education, had no barriers and were not advertisements. If both terms generated the same results, duplicated materials were excluded from the analysis. Origin of the article was categorized into non-profit, online-shop, dermatology clinic or pharmaceutical company class. Readability was evaluated with Lix score.Results: A total of 458 articles in 22 languages were evaluated. The overall mean Lix score was 57 ± 9. This classified included articles as very hard to comprehend. Across all included languages significant differences in Lix score were revealed (P 0.05).Conclusion: Despite the coverage of HS on the Internet, its complexity made it hard to comprehend. Dermatologist should ensure readable, barrier-free online educational materials. With adequate Google promotion, these would be beneficial for both physicians and patients.Keywords: hidradenitis suppurativa, online education, acne inversa, readabilit

Managing Information to Support the Decision Making Process

Decision-making is a crucial activity during the planning, design and operation of artefacts. To make a decision several alternatives must be evaluated and compared, which are tasks that require information, knowledge and expertise. A system that organises and manages the knowledge associated with every alternative and links ideas, arguments and issues can greatly improve and facilitate the decision making process. This paper presents how an Issue Based Information System (IBIS) implemented in Compendium (http://compendium.open.ac.uk) has been extended with new functionalities such as access to a toolkit of Multi-Criteria Decision Methods (MCDM), the ability to propagate values throughout the decision records and to perform sensitivity analysis of the recommended decisions with respect to a parameter. These additional functionalities enable the applicability of the system in the support of decisions that require not only argumentation, but also numerical evaluation of the properties of the alternatives such as those proposed during the design, planning and operation of engineering artefacts. </jats:p

RESULTS OF POSTSLAUGHTER EVALUATION OF CROSSBRED FATTENERS (ZŁOTNICKA SPOTTED X DUROC) AND PUREBRED FATTENERS (ZŁOTNICKA SPOTTED)

Experimental material consisted of 112 carcasses of crossbred fatteners (złp x dur) and 16 purebred animals (złp). The following traits were analyzed in postslaughter evaluation: carcass weight (kg), mean backfat thickness (mm), height of the longissimus dorsi muscle (mm) and lean meat percentage in the carcass (%). Based on the determined carcass weight and measurements of carcass leanness the carcasses were classified in the SEUROP system. Results of postslaughter evaluation indicate relatively low carcass leanness. In only 10% carcasses leanness exceeded 50 %, while 75% carcasses fell within the range from R to O in the EUROP classification. The breed of the sire had a highly significant effect on meatiness of fatteners. Pigs sired by Duroc boars were characterized by a significantly higher meatiness, irrespectively of sex, piggery, supplier and year of birth. Backfat thickness was significantly higher in the group of crosses sired by Złotnicka Spotted boars

A review of the renal system and diurnal variations of renal activity in livestock

Kidneys are the main organs regulating water-electrolyte homeostasis in the body. They are responsible for maintaining the total volume of water and its distribution in particular water spaces, for electrolyte composition of systemic fluids and also for maintaining acid-base balance. These functions are performed by the plasma filtration process in renal glomeruli and the processes of active absorption and secretion in renal tubules, all adjusted to an 'activity-rest' rhythm. These diurnal changes are influenced by a 24-hour cycle of activity of hormones engaged in the regulation of renal activity. Studies on spontaneous rhythms of renal activity have been carried out mainly on humans and laboratory animals, but few studies have been carried out on livestock animals. Moreover, those results cover only some aspects of renal physiology. This review gives an overview of current knowledge concerning renal function and diurnal variations of some renal activity parameters in livestock, providing greater understanding of general chronobiological processes in mammals. Detailed knowledge of these rhythms is useful for clinical, practical and pharmacological purposes, as well as studies on their physical performance

Phase-space dependence of particle-ratio fluctuations in Pb+Pb collisions from 20A to 158A GeV beam energy

A novel approach, the identity method, was used for particle identification and the study of fluctuations of particle yield ratios in Pb+Pb collisions at the CERN Super Proton Synchrotron (SPS). This procedure allows to unfold the moments of the unknown multiplicity distributions of protons (p), kaons (K), pions ($\pi$) and electrons (e). Using these moments the excitation function of the fluctuation measure $\nu_{\text{\text{dyn}}}$[A,B] was measured, with A and B denoting different particle types. The obtained energy dependence of $\nu_{\text{dyn}}$ agrees with previously published NA49 results on the related measure $\sigma_{\text{dyn}}$. Moreover, $\nu_{\text{dyn}}$ was found to depend on the phase space coverage for [K,p] and [K,$\pi$] pairs. This feature most likely explains the reported differences between measurements of NA49 and those of STAR in central Au+Au collisions

Measurement of event-by-event transverse momentum and multiplicity fluctuations using strongly intensive measures Δ[PT,N]\Delta[P_T, N] and Σ[PT,N]\Sigma[P_T, N] in nucleus-nucleus collisions at the CERN Super Proton Synchrotron

Results from the NA49 experiment at the CERN SPS are presented on event-by-event transverse momentum and multiplicity fluctuations of charged particles, produced at forward rapidities in central Pb+Pb interactions at beam momenta 20$A$, 30$A$, 40$A$, 80$A$, and 158$A$ GeV/c, as well as in systems of different size ($p+p$, C+C, Si+Si, and Pb+Pb) at 158$A$ GeV/c. This publication extends the previous NA49 measurements of the strongly intensive measure $\Phi_{p_T}$ by a study of the recently proposed strongly intensive measures of fluctuations $\Delta[P_T, N]$ and $\Sigma[P_T, N]$. In the explored kinematic region transverse momentum and multiplicity fluctuations show no significant energy dependence in the SPS energy range. However, a remarkable system size dependence is observed for both $\Delta[P_T, N]$ and $\Sigma[P_T, N]$, with the largest values measured in peripheral Pb+Pb interactions. The results are compared with NA61/SHINE measurements in $p+p$ collisions, as well as with predictions of the UrQMD and EPOS models.Comment: 12 pages, 14 figures, to be submitted to PR

Production of deuterium, tritium, and 3^3He in central Pb+Pb collisions at 20A, 30A, 40A, 80A, and 158A GeV at the CERN SPS

Production of $d$, $t$, and $^3$He nuclei in central Pb+Pb interactions was studied at five collision energies ($\sqrt{s_{NN}}=$ 6.3, 7.6, 8.8, 12.3, and 17.3 GeV) with the NA49 detector at the CERN SPS. Transverse momentum spectra, rapidity distributions, and particle ratios were measured. Yields are compared to predictions of statistical models. Phase-space distributions of light nuclei are discussed and compared to those of protons in the context of a coalescence approach. The coalescence parameters $B_2$ and $B_3$, as well as coalescence radii for $d$ and $^3$He were determined as a function of transverse mass at all energies.Comment: 22 pages, 29 figures, 8 tables, for submission to Phys. Rev.

Measurement of Production Properties of Positively Charged Kaons in Proton-Carbon Interactions at 31 GeV/c

Spectra of positively charged kaons in p+C interactions at 31 GeV/c were measured with the NA61/SHINE spectrometer at the CERN SPS. The analysis is based on the full set of data collected in 2007 with a graphite target with a thickness of 4% of a nuclear interaction length. Interaction cross sections and charged pion spectra were already measured using the same set of data. These new measurements in combination with the published ones are required to improve predictions of the neutrino flux for the T2K long baseline neutrino oscillation experiment in Japan. In particular, the knowledge of kaon production is crucial for precisely predicting the intrinsic electron neutrino component and the high energy tail of the T2K beam. The results are presented as a function of laboratory momentum in 2 intervals of the laboratory polar angle covering the range from 20 up to 240 mrad. The kaon spectra are compared with predictions of several hadron production models. Using the published pion results and the new kaon data, the K+/\pi+ ratios are computed.Comment: 10 pages, 11 figure

Proton -- Lambda Correlations in Central Pb+Pb Collisions at sqrt(s_{NN}) = 17.3 GeV

The momentum correlation between protons and lambda particles emitted from central Pb+Pb collisions at sqrt(s_{NN}) = 17.3 GeV was studied by the NA49 experiment at the CERN SPS. A clear enhancement is observed for small relative momenta (q_{inv} < 0.2 GeV). By fitting a theoretical model, which uses the strong interaction between the proton and the lambda in a given pair, to the measured data a value for the effective source size is deduced. Assuming a static Gaussian source distribution we derive an effective radius parameter of R_G = 3.02 \pm 0.20$(stat.)^{+0.44}_{-0.16}(syst.) fm.Comment: 14 pages, 9 figures, submitted to Phys. Rev.