Occurrence of secondary metabolites in tepals of Asphodelus ramosus L.

Major processes contributing to subtleties of ephemeral flowers of Asphodelus ramosus are related to chemical constituents detected in tepals which expand during cold and wet seasons in the eastern Mediterranean. Luteolin, caffeic acid, chlorogenic, and p-hydroxy-benzoic acids are the main constituents, whereas νalkanes, ketones, and fatty acids appear in low amounts

Activités anti-radicalaires de l'huile essentielle et des extraits bruts de Thymus numidicus Poiret., Algérie

Thymus numidicus Poiret. (Lamiaceae) est une plante largement utilisée en médecine traditionnelle algérienne pour ses propriétés thérapeutiques. Le but de ce travail est d'évaluer l'activité antioxydante de l'huile essentielle ainsi que plusieurs extraits bruts (dichlorométhane, méthanol, méthanol-eau 5:1 v/v, et l'infusé) du Thymus numidicus Poiret. récolté à Annaba (Algérie). L'activité antioxydante a été estimée par deux méthodes photométriques, la méthode de DPPH et celle de réduction du peroxyde d'hydrogène. Les résultats ont révélé que les deux extraits méthanol et méthanol-eau 5:1 ont exercé une forte activité de piégeage des radicaux libres DPPH en comparaison avec le BHT ainsi qu'une haute capacité de blocage du peroxyde d'hydrogène en comparaison avec les contrôles positifs de l'acide gallique et l'acide caféique.Mots-clés : Thymus numidicus, extraits bruts, activité antioxydante. Anti-radical activities of essential oil and crude extracts of Thymus numidicus Poiret., AlgeriaThymus numidicus Poiret. (Lamiaceae) is a plant widely used in Algerian traditional medicine. The aim of this work was to assess the antioxidant activity of the volatile compounds as well as different crude extracts (dichloromethane, methanol, methanol-water 5:1 v/v, infusion) of the endemic Thymus numidicus Poiret. collected from Annaba city (Algeria). The antioxidant activity was estimated by two fluorimetric methods, the DPPH method and the hydrogen peroxide scavenging method. The results revealed that methanol and methanol water 5:1 v/v extracts exerted very high free radical scavenging activity compared to the well-known butylated hydroxytoluene (BHT) and high hydrogen peroxide blocking activity than positive controls gallic acid and caffeic acid.Keywords : Thymus numidicus, crude extracts, anioxidant activity

Occurrence of secondary metabolites in tepals of Asphodelus ramosus L

Abstract Major processes contributing to subtleties of ephemeral flowers of Asphodelus ramosus are related to chemical constituents detected in tepals which expand during cold and wet seasons in the eastern Mediterranean. Luteolin, caffeic acid, chlorogenic, and p-hydroxy-benzoic acids are the main constituents, whereas alkanes, ketones, and fatty acids appear in low amounts

Nanovesicles loaded with origanum onites and satureja thymbra essential oils and their activity against food-borne pathogens and spoilage microorganisms

Food poisoning is a common cause of illness and death in developing countries. Essential oils (EOs) could be effective and safe natural preservatives to prevent and control bacterial contamination of foods. However, their high sensitivity and strong flavor limit their application and biological effectiveness. The aim of this study was firstly the chemical analysis and the antimicrobial evaluation of the EOs of Origanum onites L. and Satureja thymbra L. obtained from Symi island (Greece), and, secondly, the formulation of propylene glycol-nanovesicles loaded with these EOs to improve their antimicrobial properties. The EOs were analyzed by GC-MS and their chemical contents are presented herein. Different nanovesicles were formulated with small average sizes, high homogeneity, and optimal ζ-potential. Microscopic observation confirmed their small and spherical shape. Antibacterial and antifungal activities of the formulated EOs were evaluated against food-borne pathogens and spoilage microorganisms compared to pure EOs. Propylene glycol-nanovesicles loaded with O. onites EO were found to be the most active formulation against all tested strains. Additionally, in vitro studies on the HaCaT cell line showed that nanovesicles encapsulated with EOs had no toxic effect. The present study revealed that both EOs can be used as alternative sanitizers and preservatives in the food industry, and that their formulation in nanovesicles can provide a suitable approach as food-grade delivery system

Impact of Enzalutamide on Skeletal Related Events (Sres), Pain and Quality of Life (Qol) in the Prevail Trial

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Identification of essential oil components of Marrubium thessalum Boiss. & Heldr., growing wild in Greece

The essential oil of the Greek endemic species Marrubium thessalum Boiss. & Heldr. (Lamiaceae) was obtained by the hydrodistillation of its aerial parts during the flowering stage. The composition of the oil was analysed by GC and GC-MS. Thirty compounds were identified. The oil was devoid of monoterpenes, while sesquiterpenes constituted the major fraction. The main components of the oil were caryophyllene oxide (21.7%), β-caryophyllene (17.6%), germacrene D (15.3%), β-bisabolene (12.6%) and trans-β-farnesene (8.1%). © 2012 Copyright Taylor and Francis Group, LLC

Phytochemical investigation of the fern asplenium ceterach (Aspleniaceae)

The fern Asplenium ceterach L. (syn. Ceterach Officinarum Willd.) is used in lOcal traditiOnal medicine against kidney stOnes, gallstOnes, tO facilitate diuresis and tO treat benign prOstatic hyperplasia. The aim Of this study was first tO investigate the chemical cOmpOsitiOn Of this fern and then tO study the chemical prOfile Of the herbal preparatiOns used in lOcal medicine due tO its diuretic prOperties. In tOtal, nine secOndary metabOlites frOm the methanOl extract Of the aerial parts have been isOlated; three flavOnOids, namely kaempherOl-3-O-β-D-gentiObiOside (1), quercetin-3-O-β-D-glucurOnide (2), quercetin-3-O-β-DgentiObiOside (3), three phenOlic acids, i.e. Caffeic acid (4), chlOrOgenic acid (5) and p-cOumarOyl-4-O-β-D-glucOside (6), as well as three phenOls, 4-vinylphenOl- 1-O-β-D-glucOpyranOside (7), 3-(1-O-β-D-glucOpyranOsyl-4-hydrOxyphenyl)-prOpiOnic acid (8), and 4-β-O-D-glucOsyl-3,4-dihydrOxybenzyl alcOhOl (9). MOreOver, the cyclOhexane residue has been submitted tO GC-MS and NMR analyses and revealed the presence Of ethyl esters Of palmitic, linOleic and α- linOlenic acids. Finally, based On NMR, TLC and HPLC analyses, it was evident that the chemical fingerprints Of all herbal preparatiOns were quite similar, with chlOrOgenic acid being the main cOmpOund and caffeic acid present Only in traces. © 2018 Natural Product Incorporation. All rights reserved